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Onfi Alternatives Compared

View side-by-side comparisons of medication uses, ratings, cost, side effects and interactions.
Onfi Banzel Epidiolex
View side-by-side comparisons of medication uses, ratings, cost, side effects and interactions.
Onfi (clobazam) Banzel (rufinamide) Epidiolex (cannabidiol)
Prescription only

Prescribed for Lennox-Gastaut Syndrome. Onfi may also be used for purposes not listed in this medication guide.

Prescription only

Prescribed for Lennox-Gastaut Syndrome. Banzel may also be used for purposes not listed in this medication guide.

Prescription only

Prescribed for Dravet Syndrome, Lennox-Gastaut Syndrome, Tuberous Sclerosis Complex. Epidiolex may also be used for purposes not listed in this medication guide.

Related suggestions
More about Onfi (clobazam) More about Banzel (rufinamide) More about Epidiolex (cannabidiol)
Generic Status

Lower-cost generic is available

Lower-cost generic is available

No lower-cost generic available
Ratings & Reviews

Onfi has an average rating of 5.8 out of 10 from a total of 11 ratings on Drugs.com. 45% of reviewers reported a positive effect, while 36% reported a negative effect.

Banzel has an average rating of 9.5 out of 10 from a total of 6 ratings on Drugs.com. 83% of reviewers reported a positive effect, while 0% reported a negative effect.

Epidiolex has an average rating of 3.0 out of 10 from a total of 1 ratings on Drugs.com. 0% of reviewers reported a positive effect, while 100% reported a negative effect.

View all 11 reviews

View all 6 reviews

View all 1 reviews

Drug Class
Side Effects

Common side effects include:

  • constipation
  • drowsiness
  • fever
  • sedated state
  • aggressive behavior
  • ataxia
  • lethargy
  • drooling
  • irritability
  • show all 9

See also: Onfi side effects in more detail.

Common side effects include:

  • seizure
  • dizziness
  • drowsiness
  • fatigue
  • headache
  • nausea
  • vomiting

See also: Banzel side effects in more detail.

See also: Epidiolex side effects in more detail.
Pricing and Coupons * Prices are without insurance
Quantity 100 tablet
Dosage 10 mg
Per Unit* $29.03
Cost* $2,903.16

View all Onfi prices and generic prices

Quantity 460 mL
Dosage 40 mg/mL
Per Unit* $4.05
Cost* $1,861.73

View all Banzel prices and generic prices

Quantity 60 mL
Dosage 100 mg/mL
Per Unit* $16.69
Cost* $1,001.43

View all Epidiolex prices

Get free Discount Card

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Dosage Form(s) Available
  • Oral suspension
  • Oral tablet
  • Oral suspension
  • Oral tablet
  • Oral liquid
Brand Names
Other clobazam brands include: Sympazan

N/A

N/A
Half Life The half-life of a drug is the time taken for the plasma concentration of a drug to reduce to half its original value.

82 hours

10 hours

61 hours
CSA Schedule ** View glossary of terms
4
Some potential for abuse

Has a low potential for abuse relative to those in schedule 3. It has a currently accepted medical use in treatment in the United States. Abuse may lead to limited physical dependence or psychological dependence relative to those in schedule 3.
N
Not a controlled drug

Is not subject to the Controlled Substances Act.
N
Not a controlled drug

Is not subject to the Controlled Substances Act.
Pregnancy Category
C
Category C Risk cannot be ruled out

See the full pregnancy warnings document.
C
Category C Risk cannot be ruled out

See the full pregnancy warnings document.

Summary unavailable.

See the full pregnancy warnings document.
Drug Interactions

A total of 490 drugs are known to interact with Onfi:

  • 32 major drug interactions (161 brand and generic names)
  • 424 moderate drug interactions (1633 brand and generic names)
  • 34 minor drug interactions (217 brand and generic names)

A total of 470 drugs are known to interact with Banzel:

  • 7 major drug interactions (21 brand and generic names)
  • 449 moderate drug interactions (2475 brand and generic names)
  • 14 minor drug interactions (51 brand and generic names)

A total of 570 drugs are known to interact with Epidiolex:

  • 14 major drug interactions (64 brand and generic names)
  • 503 moderate drug interactions (2225 brand and generic names)
  • 53 minor drug interactions (176 brand and generic names)
Alcohol/Food/Lifestyle Interactions
  • Alcohol can increase the nervous system side effects of cloBAZam such as dizziness, drowsiness, and... View more
  • Food can enhance the levels of rufinamide in your body. To ensure maximal oral absorption... View more
  • Food may affect the absorption and blood levels of cannabidiol. To avoid significant fluctuations... View more
  • Using cannabidiol together with alcohol may increase side effects such as dizziness, drowsiness... View more
Disease Interactions
First Approval Date

October 21, 2011

November 14, 2008

June 25, 2018
WADA Class View World Anti-Doping Agency classifications.

N/A

N/A

N/A
More Information
Patient resources

N/A

N/A
Professional Resources

N/A
Related Treatment Guide

** The Controlled Substances Act (CSA) schedule information displayed applies to substances regulated under federal law. There may be variations in CSA schedules between individual states.

Further information

Always consult your healthcare provider to ensure the information displayed on this page applies to your personal circumstances.

Medical Disclaimer

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