Comparing NuvaRing vs Ortho Tri-Cyclen

View side-by-side comparisons of medication uses, ratings, cost, side effects and interactions.
NuvaRing (ethinyl estradiol / etonogestrel)	Ortho Tri-Cyclen (ethinyl estradiol / norgestimate)	Enter another drug to compare

View side-by-side comparisons of medication uses, ratings, cost, side effects and interactions.
NuvaRing (ethinyl estradiol / etonogestrel)	Ortho Tri-Cyclen (ethinyl estradiol / norgestimate)	Enter another drug to compare
Prescription only Prescribed for Birth Control. NuvaRing may also be used for purposes not listed in this medication guide.	Prescription only Prescribed for Acne, Endometriosis, Ovarian Cysts, Abnormal Uterine Bleeding, Birth Control, Gonadotropin Inhibition. Ortho Tri-Cyclen may also be used for purposes not listed in this medication guide. View more	Related suggestions Birth Control Mirena Nexplanon Lo Loestrin Fe Sprintec Depo Provera Norethindrone Popular comparisons NuvaRing vs Depo Provera NuvaRing vs Aviane NuvaRing vs Apri NuvaRing vs Blisovi Fe 1 / 20 NuvaRing vs Annovera NuvaRing vs Aurovela Fe 1.5 / 30
More about NuvaRing (ethinyl estradiol / etonogestrel)	More about Ortho Tri-Cyclen (ethinyl estradiol / norgestimate)
Ratings & Reviews
NuvaRing has an average rating of 6.0 out of 10 from a total of 1198 ratings on Drugs.com. 44% of reviewers reported a positive effect, while 29% reported a negative effect.	Ortho Tri-Cyclen has an average rating of 5.7 out of 10 from a total of 266 ratings on Drugs.com. 39% of reviewers reported a positive effect, while 32% reported a negative effect.
View all 1198 reviews	View all 266 reviews
Side Effects Experienced by Users Side effects are reported in Drugs.com user reviews and not clinically verified.
Mood swings (21.5%) Sexual dysfunction (20.6%) Depression (17.5%) Weight gain (16.9%) Cramps (12.5%) Anxiety (11.9%) Acne (11.6%) View all NuvaRing side effects	Acne (26.7%) Mood swings (26.3%) Weight gain (23.7%) Depression (19.9%) Nausea (16.9%) Cramps (15.0%) Headaches (10.2%) View all Ortho Tri-Cyclen side effects
Drug Class
Contraceptives	Contraceptives
Generic Availability
Lower cost generic approved	Lower cost generic approved
Pricing and Coupons * Prices are without insurance
We could not find an exact match for this medicine. Try searching the Price Guide directly.	We could not find an exact match for this medicine. Try searching the Price Guide directly.
Get free Discount Card	Get free Discount Card

Dosage Forms
Vaginal ring	Oral tablet
Brand Names
Other ethinyl estradiol / etonogestrel brands include: EluRyng, EnilloRing, Haloette, VeraRing	Other ethinyl estradiol / norgestimate brands include: Estarylla, Femynor, Mili, Mono-Linyah, Nymyo, Previfem, Sprintec, Tri Femynor, Tri-Estarylla, Tri-Linyah, Tri-Lo-Estarylla, Tri-Lo-Linyah, Tri-Lo-Marzia, Tri-Lo-Mili, Tri-Lo-Sprintec, Tri-Mili, Tri-Nymyo, Tri-Previfem, Tri-Sprintec, Tri-VyLibra, Tri-Vylibra Lo, VyLibra View more
Half Life Drug half-life is the time required for plasma concentration to reduce to half its original value.
45 hours	N/A
CSA Schedule ¹ View glossary of CSA terms
N Not a controlled drug Is not subject to the Controlled Substances Act.	N Not a controlled drug Is not subject to the Controlled Substances Act.
Pregnancy Category
X Category X Not for use in pregnancy See the full pregnancy warnings document.	X Category X Not for use in pregnancy See the full pregnancy warnings document.
Drug Interactions
A total of 495 drugs are known to interact with NuvaRing: 77 major drug interactions (200 brand and generic names) 370 moderate drug interactions (1377 brand and generic names) 48 minor drug interactions (525 brand and generic names)	A total of 493 drugs are known to interact with Ortho Tri-Cyclen: 75 major drug interactions (195 brand and generic names) 369 moderate drug interactions (1375 brand and generic names) 49 minor drug interactions (527 brand and generic names)
Alcohol/Food/Lifestyle Interactions
Grapefruit juice may increase the blood levels of certain medications such as etonogestrel. You... View more	Grapefruit juice may increase the blood levels of certain medications such as norgestimate. You... View more
Disease Interactions
Smoking Abnormal genital bleeding Abnormal vaginal bleeding Carcinomas (estrogenic) Hypercalcemia in breast cancer Hypertension Thromboembolism/cardiovascular Hepatic neoplasms Breast malignancy Liver disease Thromboembolism Angioedema Gallbladder disease Hypercalcemia Hyperlipidemia Liver disease Melasma Depression Fluid retention Glucose intolerance Retinal thrombosis Thyroid function tests Gallbladder disease	Smoking Abnormal vaginal bleeding Carcinomas (estrogenic) Hypercalcemia in breast cancer Hypertension Thromboembolism/cardiovascular Hepatic neoplasms Liver disease Thromboembolism Angioedema Gallbladder disease Hypercalcemia Hyperlipidemia Liver disease Melasma Depression Fluid retention Glucose intolerance Retinal thrombosis Thyroid function tests Hyperlipidemia Weight gain
First Approval Date
October 03, 2001	July 03, 1992
WADA Class View classifications
N/A	N/A
More Information
Side effects Drug interactions Dosage Pricing and coupons Pregnancy warnings Support group En español	Side effects Drug interactions Dosage Pregnancy warnings Drug images Support group
Patient Resources
NuvaRing uses	Ortho Tri-Cyclen uses
Professional Resources
Prescribing information	Prescribing information
Related Treatment Guide
Birth Control	Acne Endometriosis Ovarian Cysts Abnormal Uterine Bleeding Birth Control Gonadotropin Inhibition

¹ The Controlled Substances Act (CSA) schedule information displayed applies to substances regulated under federal law. There may be variations in CSA schedules between individual states.

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Comparing NuvaRing vs Ortho Tri-Cyclen

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