Comparing Neostigmine vs Pyridostigmine
| Neostigmine | Pyridostigmine |
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| Neostigmine | Pyridostigmine |
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Prescription only
Prescribed for Myasthenia Gravis, Reversal of Neuromuscular Blockade, Reversal of Nondepolarizing Muscle Relaxants, Urinary Retention. neostigmine may also be used for purposes not listed in this... View more |
Prescription only
Prescribed for Myasthenia Gravis, Reversal of Nondepolarizing Muscle Relaxants, Nerve Agent Pretreatment. May also be prescribed off label for Dysautonomia. |
Related suggestions Myasthenia Gravis
Reversal of Nondepolarizing Muscle Relaxants
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| More about Neostigmine | More about Pyridostigmine | ||||||||||||||||
| Generic Status | |||||||||||||||||
| Ratings & Reviews | |||||||||||||||||
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Neostigmine has an average rating of 5.5 out of 10 from a total of 2 ratings on Drugs.com. 50% of reviewers reported a positive effect, while 50% reported a negative effect. |
Pyridostigmine has an average rating of 6.9 out of 10 from a total of 48 ratings on Drugs.com. 58% of reviewers reported a positive effect, while 22% reported a negative effect. |
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| Drug Class | |||||||||||||||||
| Side Effects | |||||||||||||||||
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See also: neostigmine side effects in more detail. |
See also: pyridostigmine side effects in more detail. |
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| Pricing and Coupons * Prices are without insurance | |||||||||||||||||
View all neostigmine prices |
View all pyridostigmine prices |
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| Dosage Form(s) Available | |||||||||||||||||
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| Brand Names | |||||||||||||||||
| Bloxiverz | Mestinon, Mestinon Timespan, Regonol | ||||||||||||||||
| Half Life The half-life of a drug is the time taken for the plasma concentration of a drug to reduce to half its original value. | |||||||||||||||||
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2 hours |
N/A |
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| CSA Schedule ** View glossary of terms | |||||||||||||||||
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Not a controlled drug
Is not subject to the Controlled Substances Act. |
Not a controlled drug
Is not subject to the Controlled Substances Act. |
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| Pregnancy Category | |||||||||||||||||
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Category C
Risk cannot be ruled out
See the full pregnancy warnings document. |
Category C
Risk cannot be ruled out
See the full pregnancy warnings document. |
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| Drug Interactions | |||||||||||||||||
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A total of 102 drugs are known to interact with neostigmine:
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A total of 72 drugs are known to interact with pyridostigmine:
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| Alcohol/Food/Lifestyle Interactions | |||||||||||||||||
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No known alcohol/food interactions. This does not necessarily mean no interactions exist. Always consult your healthcare provider. |
No known alcohol/food interactions. This does not necessarily mean no interactions exist. Always consult your healthcare provider. |
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| Disease Interactions | |||||||||||||||||
| First Approval Date | |||||||||||||||||
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May 31, 2013 |
April 06, 1955 |
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| WADA Class View World Anti-Doping Agency classifications. | |||||||||||||||||
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N/A |
N/A |
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| More Information | |||||||||||||||||
| Patient resources | |||||||||||||||||
| Professional Resources | |||||||||||||||||
| Related Treatment Guide | |||||||||||||||||
** The Controlled Substances Act (CSA) schedule information displayed applies to substances regulated under federal law. There may be variations in CSA schedules between individual states.
Further information
Always consult your healthcare provider to ensure the information displayed on this page applies to your personal circumstances.