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Pyridostigmine and Upset Stomach: What Users Say

Brand names: Mestinon, Regonol, Mestinon Timespan

Upset stomach: mentioned by 4 users (6.8%)

Based on user experiences from 59 Pyridostigmine reviews, the following table shows the most commonly mentioned side effects.

All user comments are moderated by Drugs.com. Each review is verified for relevance and screened for inappropriate content. Side effects are user-reported and not clinically verified.

cramps 18.6%
diarrhea 15.3%
shortness of breath 10.2%
headaches 6.8%
muscle aches 6.8%
upset stomach 6.8%
blurred vision 5.1%
fatigue 5.1%

Reviews for Pyridostigmine

Showing 4 reviews tagged with "upset stomach". Clear filters to view all 59 reviews.
Commonly mentioned side effects
  • Anonymous
  • September 16, 2021

For Myasthenia Gravis "I was recently diagnosed with myasthenia gravis. I get double vision, droopy eyelids, muscle weakness, and muscle fatigue. I started on Mestinon 60 mg 3 x a day and 25 mg prednisolone and tapered down 5 mg every week. It worked, and I felt so much energy, but then my medication changed to Mestinon Timespan 180 mg, and it caused me very painful stomach cramps and excess flatulence and diarrhea. For 1 month, I hoped my body would get used to it, but I couldn't handle it anymore. I told my doctor, and she said to take half a tablet 1 x a day, and so far no bad side effects and only mild stomach cramps. My MG hasn't returned. I make sure to eat with the medicine and drink lots of water."

7 / 10
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25 Report
  • ran...
  • Taken for 10 years or more
  • October 3, 2021

For Myasthenia Gravis "I started taking Mestinon when I was first diagnosed in 1999. However, in 2004, I had a thyroidectomy, and I feel a lot better. I still take 6 pills a day and 2 Imuran pills, but I am doing almost 100% better than I was before the surgery. If I don't eat enough, my stomach will cramp badly, so I try to coat my stomach to prevent it. I can also tell when it's time for a dosage as well. Before the surgery, I couldn't get dressed, drive on the highway (could not see the highway signs), drive at night, the lights hurt my eyes, and I was very weak. I had to take family medical leave from work."

10 / 10
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19 Report
  • Hil...
  • Taken for 2 to 5 years
  • February 27, 2023

For Myasthenia Gravis "I have been taking Mestinon for 2 years for generalized myasthenia gravis. I take 30 mg three times a day. Unfortunately, I have severe diarrhea, stomach cramping, and other side effects including muscle cramping. I take Imodium, but sometimes it doesn’t work. I eat only rice, toast, and tea. I wish there was a better medication for MG with less side effects."

1 / 10
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12 Report

Frequently asked questions

  • Joh...
  • Taken for 6 months to 1 year
  • July 22, 2017

For Myasthenia Gravis "Medicine works well. I do experience muscle cramps, stomach aches, and muscle twitching at times. Blurred vision occasionally. Overall, satisfied with results."

9 / 10
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27 Report

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Reviews may be edited to correct grammar/spelling or remove inappropriate content. Reviews appearing to come from parties with a vested interest are not published. This information is not intended to endorse any medication and should not replace the expertise and judgment of healthcare professionals.