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Pyridostigmine and Shortness Of Breath: What Users Say

Brand names: Mestinon, Regonol, Mestinon Timespan

Shortness of breath: mentioned by 6 users (10.2%)

Based on user experiences from 59 Pyridostigmine reviews, the following table shows the most commonly mentioned side effects.

All user comments are moderated by Drugs.com. Each review is verified for relevance and screened for inappropriate content. Side effects are user-reported and not clinically verified.

cramps 18.6%
diarrhea 15.3%
shortness of breath 10.2%
headaches 6.8%
muscle aches 6.8%
upset stomach 6.8%
blurred vision 5.1%
fatigue 5.1%

Reviews for Pyridostigmine

Commonly mentioned side effects
  • Mam...
  • June 29, 2014

Pyridostigmine for Dysautonomia "I've been on 30 mg of Mestinon two times a day for about three months. I had diarrhea the first few days, more shortness of breath, and some drowsiness. After that, I started noticing improvement in my cognition (the worst part of my dysautonomia and fibromyalgia, to me), and I am able to keep 'doing' things longer than I could before. I do notice when it begins to wear off, and I may go up to three times a day on it. I'm very pleased. The only negative I have is a big increase in eyelid twitching and awful muscle spasms in my feet. My neurologist has had me start B-6 for this, and it helps a lot."

8 / 10
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57 Report
  • POT...
  • Taken for less than 1 month
  • February 17, 2017

Pyridostigmine for Dysautonomia "I started on 30 mg 2x daily. I had initial loose stools, but have gone back to constipation. I didn't get much relief from my tachycardia, and also noticed an increase in body twitches (not tremors). I'm now trying 60 mg 2x daily and I still have the increase in twitches and, most notably, headaches (worse than the normal everyday ones), and breathing issues (I already have asthma and laryngospasms). Not sure any benefit is worth these side effects, but it's only been a couple of days, so I'll give it a little more time."

3 / 10
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34 Report
  • POT...
  • Taken for less than 1 month
  • February 17, 2017

Pyridostigmine for Dysautonomia "I started on 30 mg 2x daily. I had initial loose stools, but have gone back to constipation. I didn't get much relief from my tachycardia, and also noticed an increase in body twitches (not tremors). I'm now trying 60 mg 2x daily and I still have the increase in twitches and, most notably, headaches (worse than the normal everyday ones), and breathing issues (I already have asthma and laryngospasms). Not sure any benefit is worth these side effects, but it's only been a couple of days, so I'll give it a little more time."

3 / 10
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34 Report

Frequently asked questions

  • Anonymous
  • March 31, 2012

Pyridostigmine for Dysautonomia "Started taking this a few months ago for dysautonomia and the POTS secondary to it. It helps the low blood pressure, low body temperature, and the gut transit issues. It does not help the nerve pain or cognitive impairment. Sometimes, when I take it a tad too soon (or even sometimes when I take a normal amount at a normal time), it will help my guts, but I will have a lot of difficulty breathing."

7 / 10
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37 Report
  • Mar...
  • Taken for 10 years or more
  • July 1, 2022

For Myasthenia Gravis "I am a 67-year-old woman and was diagnosed with ocular MG (double vision was my first symptom), and I tested positive for muscle and nerve damage in my neck. I started taking pyridostigmine, and within a month, the double vision stopped. That was about 10 years ago. I was taking pyridostigmine 60 mg 3 to 4 times a day, but now I just take one in the morning and whenever I need more - which is rarely. My symptoms are under control (remission), but I occasionally overwork and/or get too hot and tired, and difficulty swallowing, breathing, fatigue, etc., occur. I have a good supply of pyridostigmine on hand always, and it works wonders. I forget I have anything wrong with me. I have few limitations due to MG and am grateful for that."

10 / 10
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9 Report
  • Nay...
  • Taken for 1 to 6 months
  • June 11, 2019

Pyridostigmine for Dysautonomia "It actually made my breathing problems worse. Was started on 30 mg once a day and increased to 30 mg three times a day."

1 / 10
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23 Report

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