Comparing Lyrica vs Wellbutrin
| Lyrica (pregabalin) | Wellbutrin (bupropion) |
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| Lyrica (pregabalin) | Wellbutrin (bupropion) |
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Prescription only
Lyrica can help relieve nerve pain and control seizures but it is likely to cause drowsiness. Prescribed for Neuropathic Pain, Neuralgia, Fibromyalgia, Diabetic Peripheral Neuropathy, Postherpetic... View more |
Prescription only
Wellbutrin may be used in the treatment of depression; however, side effects may include insomnia, neuropsychiatric adverse events, or seizures. It carries a black box warning because it may cause... View more |
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| More about Lyrica (pregabalin) | More about Wellbutrin (bupropion) | ||||||||
| Ratings & Reviews | |||||||||
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Lyrica has an average rating of 6.4 out of 10 from a total of 931 ratings on Drugs.com. 53% of reviewers reported a positive effect, while 26% reported a negative effect. |
Wellbutrin has an average rating of 6.8 out of 10 from a total of 763 ratings on Drugs.com. 59% of reviewers reported a positive effect, while 22% reported a negative effect. |
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| Side Effects Experienced by Users Side effects are reported in Drugs.com user reviews and not clinically verified. | |||||||||
View all Lyrica side effects |
View all Wellbutrin side effects |
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| Drug Class | |||||||||
| Generic Availability | |||||||||
| Pricing and Coupons * Prices are without insurance | |||||||||
View all Lyrica prices |
We could not find an exact match for this medicine. Try searching the Price Guide directly. |
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| Dosage Forms | |||||||||
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| Brand Names | |||||||||
| Other pregabalin brands include: Lyrica CR | Other bupropion brands include: Aplenzin, Budeprion, Budeprion SR, Forfivo XL, Wellbutrin SR, Wellbutrin XL | ||||||||
| Half Life Drug half-life is the time required for plasma concentration to reduce to half its original value. | |||||||||
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6.3 hours |
30 hours |
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| CSA Schedule 1 View glossary of CSA terms | |||||||||
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Some potential for abuse
Has a low potential for abuse relative to those in schedule 4. Has a currently accepted medical use in treatment in the United States. Abuse may lead to limited physical dependence or psychological dependence relative to those in schedule 4. |
Not a controlled drug
Is not subject to the Controlled Substances Act. |
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| Pregnancy Category | |||||||||
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Category C
Risk cannot be ruled out
See the full pregnancy warnings document. |
Category C
Risk cannot be ruled out
See the full pregnancy warnings document. |
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| Drug Interactions | |||||||||
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A total of 287 drugs are known to interact with Lyrica:
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A total of 560 drugs are known to interact with Wellbutrin:
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| Alcohol/Food/Lifestyle Interactions | |||||||||
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| Disease Interactions | |||||||||
| First Approval Date | |||||||||
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December 30, 2004 |
December 30, 1985 |
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| WADA Class View classifications | |||||||||
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N/A |
N/A |
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| More Information | |||||||||
| Patient Resources | |||||||||
| Professional Resources | |||||||||
| Related Treatment Guide | |||||||||
1 The Controlled Substances Act (CSA) schedule information displayed applies to substances regulated under federal law. There may be variations in CSA schedules between individual states.
See also:
Further information
Always consult your healthcare provider to ensure the information displayed on this page applies to your personal circumstances.