Comparing Insulin Glargine vs Tresiba

View side-by-side comparisons of medication uses, ratings, cost, side effects and interactions.
Insulin glargine	Tresiba (insulin degludec)	Enter another drug to compare

Insulin glargine

Tresiba (insulin degludec)

Prescription only

Prescribed for Type 2 Diabetes, Diabetes - Type 1. Insulin glargine may also be used for purposes not listed in this medication guide.

Prescription only

Tresiba contains insulin degludec, an ultra-long-acting insulin that starts to work 60 minutes after administration and keeps working for up to 42 hours. Tresiba is approved for use in adults and... View more

More about Insulin glargine

More about Tresiba (insulin degludec)

Ratings & Reviews

Insulin glargine has an average rating of 4.2 out of 10 from a total of 293 ratings on Drugs.com. 25% of reviewers reported a positive effect, while 56% reported a negative effect.

Tresiba has an average rating of 4.4 out of 10 from a total of 153 ratings on Drugs.com. 29% of reviewers reported a positive effect, while 56% reported a negative effect.

View all 293 reviews

View all 153 reviews

Side Effects Experienced by Users Side effects are reported in Drugs.com user reviews and not clinically verified.

Headaches (6.5%)
Weight gain (5.8%)
Pain (4.4%)
Swelling (4.4%)
Rash (3.4%)
Anxiety (3.1%)
Blood sugar (3.1%)

View all Insulin glargine side effects

Headaches (11.8%)
Weight gain (11.8%)
Tiredness (7.8%)
Nausea (7.2%)
Dizziness (6.5%)
Bloating (5.9%)
Diarrhea (5.9%)

View all Tresiba side effects

Drug Class

Insulin

Insulin

Generic Availability

Lower cost generic

N/A

Pricing and Coupons * Prices are without insurance

Quantity	10 mL
Strength	yfgn 100 units/mL
Per unit^*	$7.72
Cost^*	$77.22

View all Insulin glargine prices

Quantity	15 mL
Strength	100 units/mL
Per unit^*	$36.85
Cost^*	$552.76

View all Tresiba prices

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Dosage Forms

Subcutaneous solution

Subcutaneous solution

Half Life Drug half-life is the time required for plasma concentration to reduce to half its original value.

24 hours

25 hours

CSA Schedule ¹ View glossary of CSA terms

Not a controlled drug

Is not subject to the Controlled Substances Act.

Not a controlled drug

Is not subject to the Controlled Substances Act.

Pregnancy Category

Category C Risk cannot be ruled out

See the full pregnancy warnings document.

Category C Risk cannot be ruled out

See the full pregnancy warnings document.

Drug Interactions

A total of 394 drugs are known to interact with Insulin glargine:

15 major drug interactions (39 brand and generic names)
358 moderate drug interactions (1889 brand and generic names)
21 minor drug interactions (210 brand and generic names)

A total of 392 drugs are known to interact with Tresiba:

15 major drug interactions (39 brand and generic names)
356 moderate drug interactions (1884 brand and generic names)
21 minor drug interactions (210 brand and generic names)

Alcohol/Food/Lifestyle Interactions

Alcohol may affect blood glucose levels in patients with diabetes. Both hypoglycemia (low blood... View more

Alcohol may affect blood glucose levels in patients with diabetes. Both hypoglycemia (low blood... View more

Disease Interactions

First Approval Date

April 20, 2000

N/A

WADA Class View classifications

N/A

More Information

Patient Resources

Tresiba uses

Professional Resources

Prescribing information

¹ The Controlled Substances Act (CSA) schedule information displayed applies to substances regulated under federal law. There may be variations in CSA schedules between individual states.

Further information

Always consult your healthcare provider to ensure the information displayed on this page applies to your personal circumstances.

Medical Disclaimer

Comparing Insulin Glargine vs Tresiba

See also:

Ozempic

Rybelsus

Mounjaro

Trulicity

Lantus

Tresiba

Victoza

Basaglar

Humalog

Levemir

Further information

Comparing Insulin Glargine vs Tresiba

See also:

Further information

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