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Tresiba (insulin degludec) Drug Interactions

A total of 872 drugs are known to interact with Tresiba (insulin degludec).

  • 20 major drug interactions
  • 760 moderate drug interactions
  • 92 minor drug interactions

Show all medications in the database that may interact with Tresiba (insulin degludec).

Check for interactions

Type in a drug name to check for interactions with Tresiba (insulin degludec).

Most frequently checked interactions

View interaction reports for Tresiba (insulin degludec) and the medicines listed below.

  • amlodipine (Norvasc)
  • aspirin (Ecotrin, Acetylsalicylic Acid, Aspir 81, Bayer Aspirin, Aspirin Low Strength, Bufferin, Arthritis Pain, Easprin, Ascriptin, Fasprin, Low Dose ASA, Buffered Aspirin, Aspir-Low, Durlaza, Ascriptin Enteric, Acuprin 81, Halfprin, Aspergum, Empirin, Bayer Children's Aspirin, Aspirin Lite Coat, Aspi-Cor, Aspirtab, Ecotrin Adult Low Strength, Ecotrin Maximum Strength, Entercote, Minitabs, St. Joseph Aspirin, Ascriptin Maximum Strength, Arthritis Foundation Pain Reliever, Bayer Aspirin with Heart Advantage, Bufferin Low Dose, Medi-Seltzer, Sloprin, St. Joseph 81 mg Chewable Aspirin, ZORprin, Aspiritab, Bayer Aspirin Extra Strength Plus, Buffex, Extra Strength Bayer, Genacote, Gennin-FC, Genprin, Litecoat Aspirin, Tri-Buffered Aspirin, Entaprin, Bufferin Arthritis Strength, Bufferin Extra Strength, Therapy Bayer, Stanback Analgesic, Norwich Aspirin, St. Joseph 81 mg Aspirin Enteric Safety-Coated, Ecpirin, Bayer Women's Aspirin With Calcium, Zero-Order Release, YSP Aspirin, Miniprin, Bayer Aspirin Regimen, Migralex, Heartline, Bayer Advanced Aspirin, Buffasal)
  • atorvastatin (Lipitor)
  • Crestor (rosuvastatin)
  • furosemide (Lasix, Diaqua-2, Lo-Aqua)
  • gabapentin (Neurontin, Gralise, Gabarone, Fanatrex)
  • glimepiride (Amaryl)
  • Humalog (insulin lispro)
  • Lantus (insulin glargine)
  • Levemir (insulin detemir)
  • levothyroxine (Synthroid, Levoxyl, Tirosint, Eltroxin, Levothroid, Levothyrox, Euthyrox, Unithroid, Levo-T, Oroxine, L Thyroxine Roche, Eutroxsig, Novothyrox, Tirosint-Sol, Levotabs, Levotec, Evotrox)
  • lisinopril (Zestril, Prinivil, Qbrelis)
  • losartan (Cozaar)
  • Lyrica (pregabalin)
  • metformin (Glucophage, Glumetza, Fortamet, Glucophage XR, Riomet)
  • Novolog (insulin aspart)
  • NovoLog FlexPen (insulin aspart)
  • omeprazole (Prilosec, Prilosec OTC, Zegerid (Original Formulation), Omesec)
  • pantoprazole (Protonix, Protonix IV)
  • Trulicity (dulaglutide)
  • Victoza (liraglutide)
  • Vitamin D3 (cholecalciferol)

Tresiba (insulin degludec) alcohol/food interactions

There is 1 alcohol/food interaction with Tresiba (insulin degludec)

Tresiba (insulin degludec) disease interactions

There are 3 disease interactions with Tresiba (insulin degludec) which include:

Drug Interaction Classification

These classifications are only a guideline. The relevance of a particular drug interaction to a specific individual is difficult to determine. Always consult your healthcare provider before starting or stopping any medication.
Major Highly clinically significant. Avoid combinations; the risk of the interaction outweighs the benefit.
Moderate Moderately clinically significant. Usually avoid combinations; use it only under special circumstances.
Minor Minimally clinically significant. Minimize risk; assess risk and consider an alternative drug, take steps to circumvent the interaction risk and/or institute a monitoring plan.
Unknown No interaction information available.

Further information

Always consult your healthcare provider to ensure the information displayed on this page applies to your personal circumstances.

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