Comparing Hydroxyurea vs Jakafi
| Hydroxyurea | Jakafi (ruxolitinib) |
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| Hydroxyurea | Jakafi (ruxolitinib) |
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Prescription only
Prescribed for Chronic Myelogenous Leukemia, Sickle Cell Anemia, Glioblastoma Multiforme, Cervical Cancer, Head and Neck Cancer, Plaque Psoriasis, Polycythemia Vera, Psoriasis, Psoriatic Arthritis... View more |
Prescription only
Prescribed for Polycythemia Vera, Myelofibrosis, Myeloproliferative Disorders, Graft Versus Host Disease. Jakafi may also be used for purposes not listed in this medication guide. |
Related suggestions Polycythemia Vera
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| More about Hydroxyurea | More about Jakafi (ruxolitinib) | ||||||||||||||||
| Ratings & Reviews | |||||||||||||||||
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Hydroxyurea has an average rating of 7.0 out of 10 from a total of 47 ratings on Drugs.com. 60% of reviewers reported a positive effect, while 21% reported a negative effect. |
Jakafi has an average rating of 7.5 out of 10 from a total of 33 ratings on Drugs.com. 67% of reviewers reported a positive effect, while 15% reported a negative effect. |
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| Side Effects Experienced by Users Side effects are reported in Drugs.com user reviews and not clinically verified. | |||||||||||||||||
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View all Hydroxyurea side effects |
View all Jakafi side effects |
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| Drug Class | |||||||||||||||||
| Generic Availability | |||||||||||||||||
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Lower cost generic |
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| Pricing and Coupons * Prices are without insurance | |||||||||||||||||
View all Hydroxyurea prices |
View all Jakafi prices |
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| Dosage Forms | |||||||||||||||||
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| Brand Names | |||||||||||||||||
| Droxia, Hydrea, Siklos, Xromi |
N/A |
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| Half Life Drug half-life is the time required for plasma concentration to reduce to half its original value. | |||||||||||||||||
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4 hours |
5.8 hours |
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| CSA Schedule 1 View glossary of CSA terms | |||||||||||||||||
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Not a controlled drug
Is not subject to the Controlled Substances Act. |
Not a controlled drug
Is not subject to the Controlled Substances Act. |
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| Pregnancy Category | |||||||||||||||||
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Category D
Positive evidence of risk
See the full pregnancy warnings document. |
Category C
Risk cannot be ruled out
See the full pregnancy warnings document. |
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| Drug Interactions | |||||||||||||||||
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A total of 288 drugs are known to interact with Hydroxyurea:
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A total of 512 drugs are known to interact with Jakafi:
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| Alcohol/Food/Lifestyle Interactions | |||||||||||||||||
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No known alcohol/food interactions. This does not necessarily mean no interactions exist. Always consult your healthcare provider. |
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| Disease Interactions | |||||||||||||||||
| First Approval Date | |||||||||||||||||
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December 07, 1967 |
November 16, 2011 |
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| WADA Class View classifications | |||||||||||||||||
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N/A |
N/A |
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| More Information | |||||||||||||||||
| Patient Resources | |||||||||||||||||
| Professional Resources | |||||||||||||||||
| Related Treatment Guide | |||||||||||||||||
1 The Controlled Substances Act (CSA) schedule information displayed applies to substances regulated under federal law. There may be variations in CSA schedules between individual states.
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Further information
Always consult your healthcare provider to ensure the information displayed on this page applies to your personal circumstances.