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User Reviews for Jakafi

Jakafi has an average rating of 6.4 out of 10 from a total of 16 ratings on Drugs.com. 56% of reviewers reported a positive effect, while 25% reported a negative effect.

Condition Avg. Rating Reviews Compare
Polycythemia Vera  
6.8
13 reviews 2 medications
Myelofibrosis  
4.7
3 reviews 2 medications
Summary of Jakafi reviews 6.4 16 reviews

Reviews may be edited to correct grammar/spelling, or to remove inappropriate language and content. Reviews that appear to be created by parties with a vested interest are not published.

Reviews for Jakafi

Cheri · Taken for 1 to 2 years September 18, 2019

For Polycythemia Vera: “A lot of people have experienced weight gain on Jakafi and I have too. For me, I only lost weight on this med by eating low carb with some form of moderate exercise when able. I also found I slept better and generally felt better on a low carb diet while taking Jakafi. Hope this helps someone else struggling with weight gain after starting this”

10 / 10
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annabanana · Taken for 6 months to 1 year November 9, 2021

For Polycythemia Vera: “I have been on Jakafi for 10 months for Polycythemia Vera. It has reduced my itching, bone and joint pain, fatigue and my counts are actually normal for the first time in decades! I have gained about 5 lbs on it but no other significant side effects. I am taking a very low amount ( 5mg 2x day) and maybe that's why I haven't gained a lot of weight. This medication has literally given me my life back.”

8 / 10
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phyrchief · Taken for 2 to 5 years June 19, 2015

For Polycythemia Vera: “This is the third Rx I've had over 10 years to treat polycythemia rubes very. Started for drug trial for 87 weeks. Now on an Rx. I've had 0 Phlebotomy since on Jakafi. Itching is nearly nonexistent. I can sleep well. Mood has improved. Generally, Jakafi has given me a life back!”

9 / 10
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Sharon Anne · Taken for 1 to 6 months August 8, 2018

For Polycythemia Vera: “I started on a higher dose and my counts came down and itching stopped, but I had weight gain! Yuck!, migraines, loud constant ringing ears, joint aches and swelling, dizziness. Then, tried a lower dose 5mg 2 x day, and side effects lessened greatly, but my counts increased. I’m off of it and on Hydrea, and trying to lose the weight now (10lbs). To add, the price of Jakafi, ruxolitinib is RIDICULOUS.”

2 / 10
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Rob15 August 23, 2017

For Polycythemia Vera: “Been taking Jakafi for 9 months .... 10mg 2x daily. Just now counts slightly increasing so my Dr is adding another 5mg daily to my dose. This med has improved my life significantly .... my over functioning has improved 100% but still with some issues. It's scary to change medications, I hope my comment will give others courage and hope ... if their Dr thinks it's worth giving it a try.”

10 / 10
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Kaude November 24, 2017

For Polycythemia Vera: “I am 74 yrs old and have polycythemia vera (PV) since I was 62. Was on Hydrea and phlobotomy every 3 mos. Was seriously very depressed and low energies. On Jakavi since May-2016 and no more phlobotomy. Now taking Jakavi 25mg twice a day. My life is back and feels like not having PV. Med is expensive at 25mg because I need 20+5 mg. Cost is doubled because they don't make 25mg pills!”

10 / 10
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zfatherhen · Taken for 1 to 2 years June 20, 2017

For Myelofibrosis: “I have post essential thrombocythemia myelofibrosis. Jakafi has my platelet count and white cell count normal again. However, it caused my red cell count to go way too low and so am on Procrit shots to avoid transfusions. I am very fatigued after the slightest physical activity. I gained about 10 pounds and get pimples from it. Jakafi instantly got rid of my joint aches and pains.”

8 / 10
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autobodyladybenz January 15, 2017

For Polycythemia Vera: “I have been on Jakafi now for 7 months. I have had major weight gain (25lbs) and migraine headaches every day. Before I started my counts were over a million and they are only down to 800,000. So for me this isn't working. The side effects and losing days to headaches are not worth taking it.”

1 / 10
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Cranny · Taken for 6 months to 1 year December 22, 2018

For Polycythemia Vera: “Took Jakafi for approximately 10 months. My itching was completely cleared up. During this entire time my bowel movements were intense. I had cramping in my stomach most mornings. Initially my dosage had to be adjusted because all of my blood levels were very low. I had developed cytopenia. Was taken off Med for 6 weeks and resumed. The last straw for me was the aching I experienced in all of my joints. Medication states a side effect can be arthralgia. Well, I got it. Had to get cortisone injections in both thumb joints, both knees, right hip and shoulder. I refuse to go back on this medication. Wish anyone able to take this Med good luck”

7 / 10
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Peggs · Taken for 6 months to 1 year October 6, 2018

For Polycythemia Vera: “I have been taking this medication, Jakafi for 10 months. Once correct dosage was figured out, I have experienced no itching and there has been no need for phlebotomy treatments. Downside to taking this medication is that for days at a time I have trouble with my bowel movements and pain and cramping in my stomach. This happens when I eat healthy, broccoli, kale, multi grain bread. Also when I eat fried foods.”

8 / 10
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Vanity · Taken for 2 to 5 years July 12, 2019

For Polycythemia Vera: “I just don't understand, I've been on this med about 2 yrs and my Dr just increased my dose to 20 mg b.i.d. My platelet count is still thru the roof ! I changed my diet and swallowing these pills just as directed! All I get is bad reports and disappointing agitated comments from my Dr ! I give up !”

1 / 10
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emma goldman October 18, 2017

For Polycythemia Vera: “I was diagnosed with polycythmia vera in 2007. Itching, terrible itching, has been my main complaint and hydroxyurea didn't help. I was taking Atarax four+ times a day plus getting light therapy 2-3 times a week. With Jakafi, I take Atarax 1-4 x day, and don't need light therapy. However, when it's really warm or allergens are in the air, I take Emend off-label. Side effects of Jakafi: more susceptible to infection, possibly anemia, possibly higher erythropoietin levels.”

8 / 10
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T-Mac · Taken for 6 months to 1 year March 6, 2021

For Myelofibrosis: “I am on Jakafi and all was going well until my Doc decided to prescribe 5 mg tablets. Well the price jumped exponentially to well over double for the same 15 days and same mg dose This he thought was needed for small adjustments. I was shocked to see my benefits eaten up almost instantly for one month of medication. I am furious and this medicine does not offer that kind of money relief. I am looking into transplant and warning others ..NEVER GET THE 5 mg Tablets!! over 34, 000 for one month prescription. No wonder my insurance is over 1,000 per month just for me..SMH”

4 / 10
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Karen · Taken for 2 to 5 years February 13, 2020

For Polycythemia Vera: “It’s either have to get a phlebotomy every month and become anemic or take Jakafi and be fat!”

5 / 10
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Kelly · Taken for 1 to 2 years April 27, 2019

For Polycythemia Vera: “It works, feel fine!”

10 / 10
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Slimpaul · Taken for 1 to 2 years March 19, 2021

For Myelofibrosis: “Been on Jakafi for over a year. Twice a day varied from 5 to 20 Mg Frankly it has done little or none for me.”

2 / 10
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This information is not intended to endorse any particular medication. While these reviews may be helpful, they are not a substitute for the expertise, knowledge and judgement of healthcare professionals.