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Jakafi and Joint Pain: What Users Say

Joint pain: mentioned by 3 users (9.1%)

Based on user experiences from 33 Jakafi reviews, the following table shows the most commonly mentioned side effects.

All user comments are moderated by Drugs.com. Each review is verified for relevance and screened for inappropriate content. Side effects are user-reported and not clinically verified.

weight gain 24.2%
itching 15.2%
fatigue 12.1%
cramps 9.1%
dizziness 9.1%
joint pain 9.1%
migraine 9.1%

Reviews for Jakafi

Showing 3 reviews tagged with "joint pain". Clear filters to view all 33 reviews.
Commonly mentioned side effects
  • ann...
  • Taken for 6 months to 1 year
  • November 9, 2021

For Polycythemia Vera "I have been on Jakafi for 10 months for Polycythemia Vera. It has reduced my itching, bone and joint pain, fatigue, and my counts are actually normal for the first time in decades! I have gained about 5 lbs on it, but no other significant side effects. I am taking a very low amount (5 mg 2x day), and maybe that's why I haven't gained a lot of weight. This medication has literally given me my life back."

8 / 10
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25 Report
  • Sha...
  • Taken for 1 to 6 months
  • August 8, 2018

For Polycythemia Vera "I started on a higher dose, and my counts came down and itching stopped, but I had weight gain! Yuck! Migraines, loud constant ringing in ears, joint aches and swelling, dizziness. Then, I tried a lower dose, 5 mg 2 x day, and side effects lessened greatly, but my counts increased. I’m off of it and on Hydrea, and trying to lose the weight now (10 lbs). To add, the price of Jakafi, ruxolitinib, is RIDICULOUS."

2 / 10
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33 Report
  • Ann...
  • Taken for 1 to 2 years
  • January 28, 2022

For Polycythemia Vera "I am 57 yrs. I have had PV for well over 20 years. I have had phlebotomies and then Hydrea and now have been on Jakafi for a year and a half. My overall experience with Jakafi is that it gave me my energy and life back. My joint pain disappeared immediately, and my energy level was amazing! I was on 5 mg 1x a day to start and then went up to 5 mg 2x a day, which I am on now. I have gained about 10 lbs, even on this low dose. Then about 6 months ago, I got shingles, I believe, from the Shingrix vaccine I had just gotten, and since then, I have not felt well. I get sick a lot, and in the past 6 months, my joint and bone pain is so much worse, almost like pre-Jakafi. The meds are working well for all blood counts right now, so I am on the fence about stopping the med."

8 / 10
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15 Report

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