Comparing Hydrocortisone vs Prednisolone
| Hydrocortisone | Prednisolone |
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| Hydrocortisone | Prednisolone |
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Prescription only
Prescribed for Adrenocortical Insufficiency, Addison's Disease, Asthma - acute, Ulcerative Proctitis, Crohn's Disease - Active, Inflammatory Bowel Disease, Inflammatory Conditions, Shock, Ulcerative... View more |
Prescription only
Prednisolone effectively controls inflammation and an overactive immune system but may not be suitable for everybody. Long-term use is limited by potentially severe side effects such as adrenal... View more |
Related suggestions Inflammatory Conditions
Asthma, acute
Crohn's Disease, Active
Popular comparisons
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| More about Hydrocortisone | More about Prednisolone | ||||||||||||||||
| Ratings & Reviews | |||||||||||||||||
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Hydrocortisone has an average rating of 7.5 out of 10 from a total of 31 ratings on Drugs.com. 68% of reviewers reported a positive effect, while 10% reported a negative effect. |
Prednisolone has an average rating of 6.4 out of 10 from a total of 48 ratings on Drugs.com. 44% of reviewers reported a positive effect, while 23% reported a negative effect. |
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| Side Effects Experienced by Users Side effects are reported in Drugs.com user reviews and not clinically verified. | |||||||||||||||||
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View all Hydrocortisone side effects |
View all Prednisolone side effects |
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| Drug Class | |||||||||||||||||
| Generic Availability | |||||||||||||||||
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Lower cost generic |
Lower cost generic |
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| Pricing and Coupons * Prices are without insurance | |||||||||||||||||
View all Hydrocortisone prices |
View all Prednisolone prices |
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| Dosage Forms | |||||||||||||||||
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| Brand Names | |||||||||||||||||
| Alkindi Sprinkle, Cortef, Cortenema, Cortifoam, Khindivi, Solu-Cortef | Millipred, Millipred DP, Orapred ODT, PediaPred | ||||||||||||||||
| Half Life Drug half-life is the time required for plasma concentration to reduce to half its original value. | |||||||||||||||||
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12 hours |
4 hours |
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| CSA Schedule 1 View glossary of CSA terms | |||||||||||||||||
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Not a controlled drug
Is not subject to the Controlled Substances Act. |
Not a controlled drug
Is not subject to the Controlled Substances Act. |
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| Pregnancy Category | |||||||||||||||||
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Category C
Risk cannot be ruled out
See the full pregnancy warnings document. |
Category C
Risk cannot be ruled out
See the full pregnancy warnings document. |
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| Drug Interactions | |||||||||||||||||
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A total of 648 drugs are known to interact with Hydrocortisone:
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A total of 636 drugs are known to interact with Prednisolone:
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| Alcohol/Food/Lifestyle Interactions | |||||||||||||||||
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No known alcohol/food interactions. This does not necessarily mean no interactions exist. Always consult your healthcare provider. |
No known alcohol/food interactions. This does not necessarily mean no interactions exist. Always consult your healthcare provider. |
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| Disease Interactions | |||||||||||||||||
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| First Approval Date | |||||||||||||||||
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December 21, 1951 |
N/A |
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| WADA Class View classifications | |||||||||||||||||
| More Information | |||||||||||||||||
| Patient Resources | |||||||||||||||||
| Professional Resources | |||||||||||||||||
| Related Treatment Guide | |||||||||||||||||
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1 The Controlled Substances Act (CSA) schedule information displayed applies to substances regulated under federal law. There may be variations in CSA schedules between individual states.
See also:
Further information
Always consult your healthcare provider to ensure the information displayed on this page applies to your personal circumstances.