Comparing Hydrochlorothiazide vs Hydrochlorothiazide / Spironolactone
| Hydrochlorothiazide | Hydrochlorothiazide / spironolactone |
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| Hydrochlorothiazide | Hydrochlorothiazide / spironolactone |
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Prescription only
Hydrochlorothiazide (HCTZ) may be used to relieve edema (fluid retention) and to lower high blood pressure. A headache, dizziness on standing, dehydration, skin reactions, and depletion of... View more |
Prescription only
Prescribed for Edema, Nephrotic Syndrome, Ascites, Heart Failure, High Blood Pressure. Hydrochlorothiazide / spironolactone may also be used for purposes not listed in this medication guide. |
Related suggestions High Blood Pressure (Hypertension)
Popular comparisons
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| More about Hydrochlorothiazide | More about Hydrochlorothiazide / spironolactone | ||||||||||||||||
| Ratings & Reviews | |||||||||||||||||
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Hydrochlorothiazide has an average rating of 5.2 out of 10 from a total of 185 ratings on Drugs.com. 35% of reviewers reported a positive effect, while 38% reported a negative effect. |
Hydrochlorothiazide / spironolactone has an average rating of 7.7 out of 10 from a total of 3 ratings on Drugs.com. 67% of reviewers reported a positive effect, while 0% reported a negative effect. |
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| Side Effects Experienced by Users Side effects are reported in Drugs.com user reviews and not clinically verified. | |||||||||||||||||
View all Hydrochlorothiazide side effects |
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| Generic Availability | |||||||||||||||||
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Lower cost generic |
Lower cost generic |
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| Pricing and Coupons * Prices are without insurance | |||||||||||||||||
View all Hydrochlorothiazide prices |
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| Dosage Forms | |||||||||||||||||
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| Brand Names | |||||||||||||||||
| Aquazide H, Carozide, Diaqua, Esidrix, Ezide, Hydro Par, Inzirqo, Microzide | Aldactazide | ||||||||||||||||
| Half Life Drug half-life is the time required for plasma concentration to reduce to half its original value. | |||||||||||||||||
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12 hours |
37 hours |
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| CSA Schedule 1 View glossary of CSA terms | |||||||||||||||||
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Not a controlled drug
Is not subject to the Controlled Substances Act. |
Not a controlled drug
Is not subject to the Controlled Substances Act. |
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| Pregnancy Category | |||||||||||||||||
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Category B
No proven risk in humans
See the full pregnancy warnings document. |
Category C
Risk cannot be ruled out
See the full pregnancy warnings document. |
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| Drug Interactions | |||||||||||||||||
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A total of 472 drugs are known to interact with Hydrochlorothiazide:
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A total of 554 drugs are known to interact with Hydrochlorothiazide / spironolactone:
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| Alcohol/Food/Lifestyle Interactions | |||||||||||||||||
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| Disease Interactions | |||||||||||||||||
| First Approval Date | |||||||||||||||||
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February 12, 1959 |
January 27, 1961 |
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| WADA Class View classifications | |||||||||||||||||
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| Related Treatment Guide | |||||||||||||||||
1 The Controlled Substances Act (CSA) schedule information displayed applies to substances regulated under federal law. There may be variations in CSA schedules between individual states.
Further information
Always consult your healthcare provider to ensure the information displayed on this page applies to your personal circumstances.