Comparing Estradiol Topical vs Premarin Vaginal
Estradiol topical | Premarin Vaginal (conjugated estrogens) |
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Estradiol topical | Premarin Vaginal (conjugated estrogens) |
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Prescription only
Prescribed for Atrophic Vaginitis, Atrophic Urethritis, Overactive Bladder, Dyspareunia. Estradiol topical may also be used for purposes not listed in this medication guide. |
Prescription only
Prescribed for Atrophic Vaginitis, Atrophic Urethritis, Postmenopausal Symptoms. Premarin Vaginal may also be used for purposes not listed in this medication guide. |
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More about Estradiol topical | More about Premarin Vaginal (conjugated estrogens) | ||||||||||||||||
Ratings & Reviews | |||||||||||||||||
Estradiol topical has an average rating of 5.1 out of 10 from a total of 489 ratings on Drugs.com. 37% of reviewers reported a positive effect, while 45% reported a negative effect. |
Premarin Vaginal has an average rating of 7.3 out of 10 from a total of 21 ratings on Drugs.com. 62% of reviewers reported a positive effect, while 19% reported a negative effect. |
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Side Effects Experienced by Users Side effects are reported in Drugs.com user reviews and not clinically verified. | |||||||||||||||||
View all Estradiol topical side effects |
View all Premarin Vaginal side effects |
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Drug Class | |||||||||||||||||
Generic Availability | |||||||||||||||||
Lower cost generic |
N/A |
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Pricing and Coupons * Prices are without insurance | |||||||||||||||||
View all Estradiol topical prices |
View all Premarin Vaginal prices |
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Dosage Forms | |||||||||||||||||
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Brand Names | |||||||||||||||||
Estrace Vaginal Cream, Estring, Imvexxy, Vagifem, Yuvafem |
N/A |
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Half Life Drug half-life is the time required for plasma concentration to reduce to half its original value. | |||||||||||||||||
N/A |
8 hours |
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CSA Schedule 1 View glossary of CSA terms | |||||||||||||||||
Not a controlled drug
Is not subject to the Controlled Substances Act. |
Not a controlled drug
Is not subject to the Controlled Substances Act. |
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Pregnancy Category | |||||||||||||||||
Category X
Not for use in pregnancy
See the full pregnancy warnings document. |
Category X
Not for use in pregnancy
See the full pregnancy warnings document. |
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Drug Interactions | |||||||||||||||||
A total of 258 drugs are known to interact with Estradiol topical:
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A total of 210 drugs are known to interact with Premarin Vaginal:
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Alcohol/Food/Lifestyle Interactions | |||||||||||||||||
No known alcohol/food interactions. This does not necessarily mean no interactions exist. Always consult your healthcare provider. |
No known alcohol/food interactions. This does not necessarily mean no interactions exist. Always consult your healthcare provider. |
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Disease Interactions | |||||||||||||||||
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First Approval Date | |||||||||||||||||
January 31, 1984 |
N/A |
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WADA Class View classifications | |||||||||||||||||
N/A |
N/A |
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More Information | |||||||||||||||||
Patient Resources | |||||||||||||||||
Professional Resources | |||||||||||||||||
Related Treatment Guide | |||||||||||||||||
1 The Controlled Substances Act (CSA) schedule information displayed applies to substances regulated under federal law. There may be variations in CSA schedules between individual states.
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Further information
Always consult your healthcare provider to ensure the information displayed on this page applies to your personal circumstances.