Comparing Depo-Provera vs Kyleena
| Depo-Provera | Kyleena |
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| Depo-Provera (medroxyprogesterone) | Kyleena (levonorgestrel) |
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Prescription only
Prescribed for Birth Control. Depo-Provera may also be used for purposes not listed in this medication guide. |
Prescription only
Prescribed for Birth Control. Kyleena may also be used for purposes not listed in this medication guide. |
Related suggestions |
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| More about Depo-Provera (medroxyprogesterone) | More about Kyleena (levonorgestrel) | ||||||||||||||||
| Generic Status | |||||||||||||||||
| Ratings & Reviews | |||||||||||||||||
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Depo-Provera has an average rating of 4.2 out of 10 from a total of 1953 ratings on Drugs.com. 28% of reviewers reported a positive effect, while 55% reported a negative effect. |
Kyleena has an average rating of 6.5 out of 10 from a total of 1597 ratings on Drugs.com. 53% of reviewers reported a positive effect, while 23% reported a negative effect. |
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| Drug Class | |||||||||||||||||
| Side Effects | |||||||||||||||||
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See also: Depo-Provera side effects in more detail. |
See also: Kyleena side effects in more detail. |
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| Pricing and Coupons * Prices are without insurance | |||||||||||||||||
View all Depo-Provera prices and generic prices |
View all Kyleena prices and generic prices |
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| Dosage Form(s) Available | |||||||||||||||||
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| Brand Names | |||||||||||||||||
| Other medroxyprogesterone brands include: depo-subQ provera 104, Provera | Other levonorgestrel brands include: Aftera, AfterPill, AfterPlan, Athentia Next, BionaFem, EContra EZ, EContra One-Step, Fallback Solo, Liletta, Mirena, Morning After, My Choice, My Way, New Day, Next Choice One Dose, Opcicon One-Step, Option 2, Plan B One-Step, PostDay One-Step, Preventeza, React, Skyla, Take Action View more | ||||||||||||||||
| Half Life The half-life of a drug is the time taken for the plasma concentration of a drug to reduce to half its original value. | |||||||||||||||||
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401 hours |
45 hours |
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| CSA Schedule ** View glossary of terms | |||||||||||||||||
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Not a controlled drug
Is not subject to the Controlled Substances Act. |
Not a controlled drug
Is not subject to the Controlled Substances Act. |
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| Pregnancy Category | |||||||||||||||||
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Category X
Not for use in pregnancy
See the full pregnancy warnings document. |
Category X
Not for use in pregnancy
See the full pregnancy warnings document. |
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| Drug Interactions | |||||||||||||||||
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A total of 220 drugs are known to interact with Depo-Provera:
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A total of 232 drugs are known to interact with Kyleena:
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| Alcohol/Food/Lifestyle Interactions | |||||||||||||||||
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No known alcohol/food interactions. This does not necessarily mean no interactions exist. Always consult your healthcare provider. |
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| Disease Interactions | |||||||||||||||||
| First Approval Date | |||||||||||||||||
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September 23, 1960 |
September 16, 2016 |
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| WADA Class View World Anti-Doping Agency classifications. | |||||||||||||||||
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N/A |
N/A |
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| More Information | |||||||||||||||||
| Patient resources | |||||||||||||||||
| Professional Resources | |||||||||||||||||
| Related Treatment Guide | |||||||||||||||||
** The Controlled Substances Act (CSA) schedule information displayed applies to substances regulated under federal law. There may be variations in CSA schedules between individual states.
Further information
Always consult your healthcare provider to ensure the information displayed on this page applies to your personal circumstances.