Comparing Amantadine vs Sinemet
| Amantadine | Sinemet (carbidopa / levodopa) |
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| Amantadine | Sinemet (carbidopa / levodopa) |
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Prescription only
Amantadine may be used to treat dyskinesia or reduce the number of OFF episodes in those with Parkinson's disease (PD) OR in the treatment or prevention of Influenza A viral infection. Nausea... View more |
Prescription only
Sinemet is a medication that may be used for the treatment of Parkinson's disease that is available in three different strengths: Sinemet 25/100, Sinemet 25/250, and Sinemet 10/100. Dyskinesias... View more |
Related suggestions |
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| More about Amantadine | More about Sinemet (carbidopa / levodopa) | ||||||||||||||||
| Ratings & Reviews | |||||||||||||||||
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Amantadine has an average rating of 7.0 out of 10 from a total of 55 ratings on Drugs.com. 62% of reviewers reported a positive effect, while 20% reported a negative effect. |
Sinemet has an average rating of 7.6 out of 10 from a total of 31 ratings on Drugs.com. 65% of reviewers reported a positive effect, while 10% reported a negative effect. |
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| Side Effects Experienced by Users Side effects are reported in Drugs.com user reviews and not clinically verified. | |||||||||||||||||
View all Amantadine side effects |
View all Sinemet side effects |
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| Drug Class | |||||||||||||||||
| Generic Availability | |||||||||||||||||
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Lower cost generic |
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| Pricing and Coupons * Prices are without insurance | |||||||||||||||||
View all Amantadine prices |
View all Sinemet prices |
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| Dosage Forms | |||||||||||||||||
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| Brand Names | |||||||||||||||||
| Gocovri, Osmolex ER | Other carbidopa / levodopa brands include: Atamet, Crexont, Dhivy, Duopa, Parcopa, Rytary | ||||||||||||||||
| Half Life Drug half-life is the time required for plasma concentration to reduce to half its original value. | |||||||||||||||||
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19 hours |
2.3 hours |
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| CSA Schedule 1 View glossary of CSA terms | |||||||||||||||||
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Not a controlled drug
Is not subject to the Controlled Substances Act. |
Not a controlled drug
Is not subject to the Controlled Substances Act. |
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| Pregnancy Category | |||||||||||||||||
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Category C
Risk cannot be ruled out
See the full pregnancy warnings document. |
Category C
Risk cannot be ruled out
See the full pregnancy warnings document. |
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| Drug Interactions | |||||||||||||||||
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A total of 131 drugs are known to interact with Amantadine:
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A total of 521 drugs are known to interact with Sinemet:
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| Alcohol/Food/Lifestyle Interactions | |||||||||||||||||
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No known alcohol/food interactions. This does not necessarily mean no interactions exist. Always consult your healthcare provider. |
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| Disease Interactions | |||||||||||||||||
| First Approval Date | |||||||||||||||||
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February 14, 1968 |
May 02, 1975 |
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| WADA Class View classifications | |||||||||||||||||
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N/A |
N/A |
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| More Information | |||||||||||||||||
| Patient Resources | |||||||||||||||||
| Professional Resources | |||||||||||||||||
| Related Treatment Guide | |||||||||||||||||
1 The Controlled Substances Act (CSA) schedule information displayed applies to substances regulated under federal law. There may be variations in CSA schedules between individual states.
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Ingrezza
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Banophen
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Benadryl Allergy
Benadryl Allergy is used for allergic reactions, allergic rhinitis, allergies, cold symptoms ...
Artane
Artane is used for cerebral spasticity, extrapyramidal reaction, parkinson's disease
Gocovri
Gocovri (amantadine) is used in the treatment of Parkinson's disease. Includes Gocovri side ...
Trihexyphenidyl
Trihexyphenidyl is used for cerebral spasticity, extrapyramidal reaction, parkinson's disease
Benztropine
Benztropine is used for extrapyramidal reaction, hyperhidrosis, parkinson's disease
Further information
Always consult your healthcare provider to ensure the information displayed on this page applies to your personal circumstances.