Zoledronic acid for Osteolytic Bone Lesions of Multiple Myeloma User Reviews

• Sun...
• March 30, 2018

Zoledronic acid "I started Zometa IV once a month for 6 years after having 2 stem cell transplants. Diagnosed with multiple myeloma 12 years ago. During the last 2 years of Zometa, I developed osteonecrosis in my jaw, BRONJ, after having a tooth extracted. That led to a domino effect, causing all my lower teeth to need to be removed. I was a 48-year-old woman when first diagnosed with MM, Stage 4. I was very physically active and had teeth. I opted to stop taking Zometa as soon as the first tooth extracted showed difficulty in healing. I am now almost 60 years old and have been off Zometa for 4 years and have had no bone fractures or breaks. I had the achy bones and the cruddy feeling for a few days. Be fanatical about oral hygiene."

• zop...
• May 9, 2012

Zoledronic acid "I've been getting the infusions for almost 2 years now. The side effects are at a manageable level (compared to what I'm used to with other medicines I've been on for multiple myeloma). It is unknown how much longer I will be getting the infusions, as it varies from patient to patient. I would consider my quality of life as good as it gets, with only a temporary interruption every 3 months."

• Ste...
• Taken for 2 to 5 years
• January 8, 2017

Zoledronic acid "I started on Zometa about 3 years ago. At first, it was every three months, but over the past year I have it every 4 weeks. The side effects vary almost every time, sometimes it's aching bones or muscle pain, and I usually feel weary to the point that I stay in bed all day. The effects usually hit me on the second day after having the infusion and only last for one day. Today is Sunday, and I had the infusion on Friday, so as I write this, I'm feeling pretty rotten, but come tomorrow I'll be feeling much better, so it doesn't worry me at all... and it's a lot better than having my bones snapping just because I've lifted something that's too heavy."

• Anonymous
• Taken for 2 to 5 years
• March 29, 2016

Zoledronic acid "My mother was on this IV treatment for about 3 years when she was first diagnosed with multiple myeloma. The only side effect at the time was nausea. 3 years later, she is now experiencing osteonecrosis of the jaw due to this treatment. I guess my view on it is the treatment is it helped at the time to prevent any more lesions, but now the bone in her jaw is dying and causing lots of pain. She just had surgery on her jaw to remove the dead bone and hopefully heal."

• Jim...
• Taken for less than 1 month
• September 13, 2016

Zoledronic acid "This new 20 min IV just about killed me and put me in the hospital for 7 days, then rehab for 2 weeks. I had chronic upper thigh pain which made my right leg and foot numb, and I need a walker to walk now. My calves also are very painful. This IV stopped my urination, and I had to go to the ER. My urethra tube was completely closed, and the urologist got 3 1/2 liters off my bladder. I have to now have a catheter for the rest of my life. My kidneys did turn around but were very bad in the hospital. I have stage 4 prostate cancer and was on Adriamycin and Lupron shot every 3 months. The Adriamycin IV was 2 hrs. I handled these meds very well, but my new oncologists decided to change to Zometa. I was not told about all of these side effects."

• Sed...
• Taken for 1 to 6 months
• July 17, 2021

Zoledronic acid "I was placed on Zometa by my oncologist as a preventive medication to avoid bone lesions and fractures. I was diagnosed with multiple myeloma earlier in the year. I fortunately do not have bone issues at this point, however, my doctor thought it might help with prevention. After my first infusion, I developed severe chills, fever, and terrible calf pain 24 hours later. The fever, chills, and pain fortunately disappeared about a day or two later, but the fatigue lasted for days. Before my second monthly infusion, I drank more water. This did seem to help with avoiding chills and fever, but 24 hours later, I again developed bad calf pain and realized I had edema in my legs. A day later, it is better, but again, I have horrible fatigue and bloating. The side effects of this medicine are worse than those of my cancer meds. I will have to talk to my doctor, as I am not willing to do this every month unless I really have to."

• Tan...
• Taken for 1 to 6 months
• October 7, 2019

"I am currently having infusions once a month. The first month was Sept 19, and it took 7 days before it sunk in. Then I was feeling it throughout my body, with pain in the larger joints. Any sports injuries I had show up also as pain. Just had the second infusion 4 days ago, I have some of those same pains in the joints starting today. I do get a balance issue at times, usually focusing on the computer screen. I'm also on Xtandi and Trelstar, each has the same side effects, plus a new one of their own! I have had minor anxiety attacks and some confusion, but they quickly go away with water. I'm always feeling like I've done something wrong. If you stay busy, these go away also."

• nik...
• Taken for 2 to 5 years
• March 7, 2021

Zoledronic acid "I found being on this for a few years increased my bone density from MINUS 4.2 down to 3.9. Would recommend it."