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Upadacitinib for Rheumatoid Arthritis User Reviews (Page 5)

Brand names: Rinvoq, Rinvoq LQ

Reviews for Upadacitinib

Commonly mentioned side effects
  • Har...
  • Taken for 1 to 2 years
  • June 21, 2025

Upadacitinib "Rinvoq is literally a godsend. Within one week, my RA calmed down, and I haven’t had a flare since. I also have an undiagnosed stomach issue that I believe is IBS-C, and within one month of taking Rinvoq, all symptoms disappeared! I didn’t get the correct paperwork to Abbie for the trial, and I went without for 4 weeks. I have been absolutely miserable! All symptoms returned with a vengeance!"

10 / 10
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  • Mol...
  • May 2, 2021

"I was on Humira, but it wasn’t lasting two weeks. My rheum wanted to try another injectable, but my insurance wouldn’t cover it until I failed this class of meds. This is the worst my RA has ever been! This seems to do worse than nothing! I have a bunch of edema in my feet and ankles now, too, not to mention what is in my knuckles. I can barely open a door handle by myself now, and I am only 40."

1 / 10
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  • Ano...
  • Taken for 10 years or more
  • August 9, 2025

Upadacitinib "Was invited on a new drug trial after 4 years of various viral infections; pleural effusions; pneumonia, shingles, etc. and none of the 4 or 5 treatments I went through were very effective. I was reliant on prednisone for pain relief. Within a month of starting the trial on Rinvoq, my flares stopped, joint pain and swelling gone, and to this day (now 10 years+) no viruses and no hospital visits. Over the last couple of years (I'm now 68), I've had some significant weight loss and diarrhea for which, after internal cameras and scans, has cleared me of nasties. I'm back to the rheumatologist in a couple of weeks for checkup and recommendation on pain relief for chronic back problems. Great to get older... Personally, this drug gave me back my life."

9 / 10
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Frequently asked questions

  • Ano...
  • Taken for 1 to 2 years
  • May 21, 2025

Upadacitinib "I have taken Rinvoq 15 mg since February 2024. It has turned my life around in terms of rheumatoid arthritis - I am more active, with less fatigue and much less pain. However, I have been sicker in this last year than ever before - pneumonia, RSV, COVID, one bout of cellulitis. Bloodwork is fine. Now, I am flare-free and only have some dull aches in my thumbs when I lift something like a half-gallon carton of milk. Before Rinvoq, I was on the classic triple therapy - methotrexate injections, max dose of sulfasalazine, and max dose of hydroxychloroquine. And while it worked for more than 10 years, those meds stopped being effective - I had almost daily new flares in my hands, wrists, and ankles."

10 / 10
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  • Dee...
  • Taken for 1 to 6 months
  • August 5, 2020

Upadacitinib "I was on Humira and Rasuva injections, as well as several oral meds. I am off all of them except Rinvoq. And I feel great!"

10 / 10
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  • Deb...
  • Taken for 1 to 6 months
  • January 1, 2021

Upadacitinib "This was my 10th medication in 2 years, and we finally found one that works for me-hurray! Started feeling better within 2 weeks. Life-changing."

10 / 10
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32 Report
  • Anonymous
  • Taken for 1 to 6 months
  • September 18, 2021

Upadacitinib "Been on Rinvoq a little over a month, it was working great until my leg got very painful and inflamed. Found out that there were blood clots in there caused by the Rinvoq :-(."

2 / 10
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24 Report
  • My...
  • Taken for 6 months to 1 year
  • August 14, 2021

Upadacitinib "This has been the best medicine. I feel like I do not have RA now. It worked quickly. Easy."

10 / 10
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18 Report
  • Liv...
  • Taken for less than 1 month
  • October 16, 2021

Upadacitinib "My skin is breaking out after taking Rinvoq. Never had this problem in my life. It's not just my face, it's all over my body. It's only been 3 weeks. I guess it's time to talk to my doctor."

3 / 10
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15 Report
  • Anonymous
  • Taken for 1 to 2 years
  • March 21, 2023

Upadacitinib "Amazing medicine, has treated my rheumatoid well. No pain after meds used. Once per day."

10 / 10
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  • Ste...
  • Taken for 2 to 5 years
  • February 2, 2024

Upadacitinib "Have been on Rinvoq for almost 4 years now. No RA symptoms anymore, but catching colds very easily."

9 / 10
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  • Dud...
  • Taken for 2 to 5 years
  • February 21, 2025

Upadacitinib "Rinvoq 15 mg daily for over 4 years, no flare-ups. Previous medications didn't work."

8 / 10
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  • sus...
  • Taken for 1 to 2 years
  • October 26, 2023

Upadacitinib "Made a huge difference to me. I have tried all the other meds, but this one is working for me. Hands looser and no swelling and much less pain."

10 / 10
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  • Ker...
  • Taken for 1 to 6 months
  • September 2, 2024

Upadacitinib "It seems to help. The side effects are brutal. Always exhausted. Always wake up feeling sick with a cold. I think my heart rate is accelerated. I only take it every other day."

5 / 10
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  • Sue...
  • Taken for 6 months to 1 year
  • November 8, 2022

Upadacitinib "Rinvoq has been a miracle for me. Within weeks of starting it, my pain and swelling diminished. The benefits far outweigh the side effects. 11 months now and I'm literally pain-free."

10 / 10
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  • Ano...
  • Taken for 2 to 5 years
  • April 30, 2025

Upadacitinib "It has almost eliminated my hand and feet pain but at a cost. I think I have had every side effect listed. Currently, folliculitis is bad and non-healing sores on my face."

8 / 10
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  • ABG...
  • Taken for 1 to 6 months
  • May 27, 2023

Upadacitinib "It's helped my hands, which were hurting pretty badly. I'd been on Humira for years, and it was becoming less effective, so I switched. I have noticed having a little less fatigue."

9 / 10
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3 Report
  • Lee...
  • Taken for 2 to 5 years
  • February 16, 2024

Upadacitinib "Effective management for rheumatoid arthritis. Possibly skin blemishes."

10 / 10
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  • BJD...
  • Taken for 1 to 6 months
  • December 5, 2024

Upadacitinib "I have been taking Rinvoq for over a year and a half. It really slowed down deformities. I had energy, but I had a bad reaction, causing embolism other than clotting. We were a good team."

6 / 10
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  • RMi...
  • Taken for 1 to 6 months
  • July 2, 2024

Upadacitinib "Works well but caused acne on face, extreme tiredness, frequent urination, massive eye bags"

8 / 10
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  • lis...
  • Taken for 1 to 6 months
  • June 10, 2024

Upadacitinib "I've been taking Rinvoq for a few weeks. At first, it was okay, but now I have blisters in my mouth. I cannot eat. I don't know what's going on."

4 / 10
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  • Val...
  • Taken for less than 1 month
  • June 18, 2025

Upadacitinib "So far I only have had one dose, but so far it’s working. I’ve had a mild headache and slight breathing issues, but I feel better after sitting down and relaxing. So far so good."

6 / 10
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  • Ano...
  • Taken for 1 to 6 months
  • August 6, 2025

Upadacitinib "Myalgia and increased weakness of legs with increasing difficulty in walking."

6 / 10
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  • Ano...
  • Taken for 1 to 2 years
  • July 12, 2025

Upadacitinib "Symptoms of RA disappeared within days; I have been pain-free for over 12 months with no obvious side effects."

10 / 10
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  • Lac...
  • Taken for 1 to 6 months
  • April 12, 2021

"I was on Rinvog for 2 months and had to go off because my white blood cells dropped too low. I do not believe it was working for me anyways."

2 / 10
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Reviews may be edited to correct grammar/spelling or remove inappropriate content. Reviews appearing to come from parties with a vested interest are not published. This information is not intended to endorse any medication and should not replace the expertise and judgment of healthcare professionals.

Learn more about Rheumatoid Arthritis

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Symptoms and treatments

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