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Trimethoprim and Anxiety: What Users Say (Page 2)

Brand names: Primsol

Reviews for Trimethoprim

Commonly mentioned side effects
  • Thi...
  • November 30, 2020

For Bladder Infection "Bladder infection. Almost an hour later, I had severe dizziness, hot flashes, extreme anxiety, and felt like my blood pressure had dropped drastically. The next 3 days, I had a horrible headache, nausea, the worst fatigue ever, completely no appetite, and severe anxiety. Kidneys were very painful, hard to breathe without exacerbating the pain. On the 4th night, I experienced all that and insomnia/strange random thoughts at night that seemed to have a mind of their own. Day 5, I feel much more like myself but still delicate. I notified my doctor and NHs24 about my symptoms, and they said to keep taking it! Glad I did because I am feeling much better now. Look up 'bacteria die-off symptoms', this may be what we have been experiencing. Harmful endotoxins from the dead bacteria in our systems due to antibiotics. I've read the worse you feel during die-off, the more you needed it. Take a good probiotic at night to ease symptoms."

6 / 10
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  • nkw...
  • Taken for less than 1 month
  • March 1, 2023

"I took the first dose and started to feel anxious, but continued taking it, and by the second day, I had the worst anxiety attack ever. Obsessive thoughts were nonstop, racing in my head. I was unable to sleep. Chills, shaking, thirst that never went away, and the worst symptom by far was the anxiety. I really would not recommend it unless it is the only choice. I had to switch antibiotics because of the side effects. Luckily, I didn't take a lot of the medicine because it was intense for the one day I took it."

1 / 10
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  • Ace...
  • Taken for less than 1 month
  • October 11, 2021

For Urinary Tract Infection "At first, I took a couple of Amoxicillin, and my symptoms had nearly gone by the time I had my appointment. My doc, for some reason, prescribed me this. Took my first dose last night for UTI. Got up and nearly fell into the wall, I was so dizzy. Couldn’t sleep at all last night until about 10 hours after taking the pill. Experienced anxiety, however, I do suffer from anxiety, but it’s medicated and generally okay. Still a little dizzy this morning, and my UTI symptoms have started to come back. :( Going back to get more Amoxicillin!"

4 / 10
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Frequently asked questions

  • Tal...
  • Taken for less than 1 month
  • October 12, 2021

For Urinary Tract Infection "I was put on Trimethoprim 200 mg tablets twice a day. After the 1st day, I did get a racing heart, but that stopped after the 2nd day. After that, I experienced feeling really, really low, depressed, not wanting to leave the house, and when I did, I felt very shaky and nervous. I have never felt like this before in my life, and I have never experienced this after taking any other antibiotic. I told the pharmacist about the symptoms/side effects, and she told me to notify my doctor/GP, which I did, and she said that when I complete the course (I was on day 6 of a 7-day course), after a few days, I should feel better. She said she won't prescribe this particular antibiotic to me in the future."

3 / 10
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  • Ang...
  • Taken for less than 1 month
  • February 27, 2023

For Urinary Tract Infection "Was prescribed a 7-day course (think curse would be a better word) for a suspected UTI. Day 3 started feeling a bit weird/off-kilter. Very anxious, tired, loss of appetite, bloating, chronic abdomen pain, but persevered as instructed by GP. Day 5, in bits!! Not sleeping, aching, anxiety borderline manic. By day 6, I honestly thought I was dying and was about to go to A&E. Finished the course but will NEVER use it again. Stay away from it, ask your GP for an alternative."

1 / 10
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  • Ang...
  • Taken for less than 1 month
  • February 27, 2023

For Urinary Tract Infection "Was prescribed a 7-day course (think curse would be a better word) for a suspected UTI. Day 3 started feeling a bit weird/off-kilter. Very anxious, tired, loss of appetite, bloating, chronic abdomen pain, but persevered as instructed by GP. Day 5, in bits!! Not sleeping, aching, anxiety borderline manic. By day 6, I honestly thought I was dying and was about to go to A&E. Finished the course but will NEVER use it again. Stay away from it, ask your GP for an alternative."

1 / 10
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  • Vit...
  • Taken for less than 1 month
  • April 4, 2022

For Urinary Tract Infection "I was prescribed this medication, as I had sepsis about 4 weeks ago. They think it's due to an infected gall bladder which the duct is blocked with stones. I can't take any of the -cillin family of antibiotics, so I was prescribed other antibiotics 2 weeks ago. They didn't work, so I was prescribed these. The first day I was fine, the second day I started feeling yuck and not wanting to go out. The second night, I struggled with anxious, horrible feelings which I don't normally have. On the third day, I realized it was these tablets when I looked online and read the reviews. I don't think these should be prescribed at all. I'd rather have sepsis again than feel how I did on this medication. Avoid."

1 / 10
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  • Bob...
  • Taken for less than 1 month
  • December 4, 2021

For Urinary Tract Infection "Horrific. Woke up from a nap on the first day of taking with suicidal ideas. Staying in an apartment and had balcony visions. Suffer with PTSD but not suicidal. Currently on holiday, so panic disorder has set in but has been massively exemplified by this antibiotic. Was prescribed a 5-day dose, stopped taking after day 3. Still feeling side effects and wondering if I’ll return to normal or whether this is it now."

1 / 10
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  • Rub...
  • Taken for less than 1 month
  • September 25, 2021

For Urinary Tract Infection "I was prescribed a 7-day course of this antibiotic, as the 3-day course of Nitrofurantoin did not work, but I think they would have done the job if the course was for 7 days, as I never had any of the symptoms I have with Trimethoprim. All the symptoms I had along with the UTI were awful, exactly as others have described, i.e., couldn’t sleep, felt very sick, was sick, as I just had no appetite for 5 days whilst in them. These tablets should make you feel better, not suicidal. Had a terrible headache and felt weird, and anxiety thoughts went through the roof, ended up in A&E on the second day. I have taken 5 ½ days' worth and now binned the others and will take my chances. I will also let my doctor know."

6 / 10
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  • Pan...
  • Taken for less than 1 month
  • August 29, 2022

For Bladder Infection "Oh my God, absolutely awful stuff. I've had anxiety for years, so I know my body and panic attacks, etc. Day 5 of these, and my manager had to call 999 as I genuinely thought I was dying. The MOST intense panic attack I've ever had. Heart thumping through my chest, faint, head spinning, hands and legs numb, weak... this was all after days of constant anxiety and dizziness. I've come off them and am still feeling dizzy, but hoping they'll wear off soon. Never again!!!!!"

1 / 10
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  • Ano...
  • Taken for less than 1 month
  • March 2, 2022

"My teenage daughter was prescribed trimethoprim to treat severe bacterial acne. She was prescribed 300 mg twice a day. Within 2 days, it was clear that it did not suit her. She became very anxious, had racing thoughts, trembling, and a very low mood, she was crying all the time. Although she suffers from anxiety, she had been enjoying an anxiety-free period for a number of months. We decided to stop the medication, and she was back to normal after 2 days. We tried trimethoprim again recently, at a lower dose of 400 mg per day, but within 3 days, she became anxious, had a low mood, and very vivid dreams. We have now stopped this medication."

1 / 10
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  • Haz...
  • Taken for less than 1 month
  • April 13, 2021

For Bladder Infection "Was prescribed this for a UTI, made me so ill, nausea, terrible constant headache, upset stomach, sweats, chills. I never slept when on them, had weird dreams, and made me anxious. I will never take again and would just rather suffer with the UTI."

1 / 10
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  • Tri...
  • Taken for less than 1 month
  • January 9, 2022

For Urinary Tract Infection "Had a water infection. 7 days of trimethoprim 200 mg prescribed by my G.P. at one tablet twice daily. My infection did go, but I felt so nauseous and spaced out after day 2 of taking them. Day 6, I nearly stopped as I felt anxious for no reason and wanted to eat, but the nausea made it difficult! Horrid side effects for me."

3 / 10
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  • Nat...
  • Taken for less than 1 month
  • September 26, 2022

For Urinary Tract Infection "Got prescribed trimethoprim for 4 days for a UTI. First dose felt a little anxious but tried to ignore it. Did feel strange for a few hours, though. Second dose I didn’t feel anything till I fell asleep and woke up an hour or two later and was having weird visions/dreams. I don’t know what they were, but they kept waking me up, and when I tried to open my eyes, they were shaky, and I struggled to keep them open. Felt really paranoid, major dissociation, and just not myself. Decided to stop taking after day 2. The UTI symptoms have gone away, but it left me feeling off mentally, and hopefully, I will return back to my normal self soon. Avoid this drug if you struggle with mental health or are sensitive to medication."

1 / 10
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  • Man...
  • Taken for less than 1 month
  • June 23, 2022

For Urinary Tract Infection "I took my first dose of trimethoprim around 6 pm last night. I started with a mild stomach ache about an hour after, and by 9 pm, I began to get blurred vision and feel very light-headed. At one point, I thought I was going to pass out, so I had to stop what I was doing and lay down. I was then getting heart palpitations and felt very anxious and was having scary thoughts that something bad was going to happen to me. I had to get my ex-partner round to come take care of my 2-year-old son as I didn’t feel capable of doing so! I was up several times in the night with a desperate urge to pee. I've woken up this morning still feeling slightly light-headed and confused, I can’t seem to think straight. My body is very achy, and I've had to come back to bed, hoping these side effects wear off soon. I refuse to take any more tablets, I’d much rather have the UTI. I really don’t know how this drug is legal."

1 / 10
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  • Anonymous
  • Taken for less than 1 month
  • April 16, 2022

For Urinary Tract Infection "Day 1, an hour after taking this, felt so tired, couldn’t move off the sofa. Carried on taking them twice a day, then the 2nd day, very fast heart rate even when resting, & started to get very shaky in my hands and just felt overwhelmed with anxiety and felt shaky inside. Managed 3 days of these and had to stop, had really bad insomnia last night before I took one, heart racing, anxious, this morning I feel totally out of it. Will never take these ever again!"

1 / 10
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  • Jul...
  • Taken for less than 1 month
  • August 9, 2022

For Urinary Tract Infection "The worst ever. I was given a 3-day course of trimethoprim for a UTI. I already suffer from severe anxiety disorder and have a hiatus hernia. Also, getting over the 2nd dose of COVID. Took the 1st tablet yesterday and felt like my throat had swollen. It eventually settled. Took the 2nd pill at bedtime, then kept waking and feeling weird and having visions or dreams. Today, I haven't taken any more and feel terrible, like I've got a fever, bad anxiety, been crying, and shaking. I hope it comes out of my system soon. For sure, it should be given to anyone knowing my luck, the UTI will still be lingering because I didn't take the full course, but screw that. Can't deal with this overwhelming clammy heat in my body, no energy, and also no appetite."

1 / 10
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  • Fox...
  • Taken for less than 1 month
  • April 19, 2021

For Bladder Infection "Desperate have read comments which leads me to believe trimethoprim might be making me feel so dreadful. I have prostatitis and have just done my 3rd week on this drug, having been on ciprofloxacin for 10 days prior to the trimethoprim (changed due to possible tendon problems taking ciprofloxacin). I became constipated within 2 days, tried to tough it out with a combination of laxatives, but just feel dragged down, very anxious, morbid thoughts, no energy, and now shaky and worried about the persistent pain. I hope this is the cause of my problems others have intimated, so that if I stop it, these problems will go away."

1 / 10
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  • Kay...
  • Taken for 1 to 6 months
  • October 1, 2022

For Urinary Tract Infection "I was placed on it for an embedded UTI, it does get rid of my pain, but the side effects aren't worth it. I was fine the first month, then, the second month, things went downhill suddenly. When I'd have a BM, my heart rate would drop to 40 bpm, and I'd almost pass out. Then, for the next 24 hours, I'd feel miserable, vomit endlessly, and would question going to the ER or psych hospital because my anxiety was so bad and intrusive thoughts-absolutely terrifying. This happened to me four times, and I decided to stop the antibiotic. It's been almost a week since stopping, still have occasional all-over body tremors/shakes, nausea is hanging on, stomach is up and down, but no BP crashes, which is great. I just hope to feel better soon."

1 / 10
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  • Anonymous
  • Taken for less than 1 month
  • May 10, 2018

For Urinary Tract Infection "Caused extreme depression, anxiety, and panic."

1 / 10
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23 Report
  • Tro...
  • July 25, 2020

For Urinary Tract Infection "Trimethoprim was awful. I was given it for a UTI! Literally had anxiety for hours. Dry mouth. And cannot settle to sleep. Hate these, so I'm not taking."

1 / 10
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12 Report
  • Fif...
  • Taken for less than 1 month
  • August 18, 2021

For Bladder Infection "Never ever will take these again! Panic attacks, shaking, feeling anxious, depressed, awful."

1 / 10
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8 Report

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Reviews may be edited to correct grammar/spelling or remove inappropriate content. Reviews appearing to come from parties with a vested interest are not published. This information is not intended to endorse any medication and should not replace the expertise and judgment of healthcare professionals.