Tirzepatide for Weight Loss (Obesity/Overweight) User Reviews (Page 4)

• All...
• Taken for 1 to 6 months
• April 22, 2025

"My insurance won't cover Zepbound. I get it through the 'Lilly Direct Cash Pay for Zepbound vials.' I started with 2.5 mg for 1 month and lost 12 pounds. I moved up to 5 mg and lost 30 pounds in 4 months. Total loss so far, 42 pounds! Starting weight was 184, height is 5'3'. Current weight is 142. Only side effect for me is seldom nausea. Price is $504 each month, and that includes the needles, otherwise, it's $499. Now that Lilly offers the higher doses for the same price, next week I start 7.5 mg. I will update again in a month or so."

• cod...
• Taken for 1 to 6 months
• February 19, 2025

"It's too early to say that Mounjaro has been life-changing, but it is certainly trending that way. My first week was a huge drop in water weight; I lost about 11 pounds. Weeks 2-4 it slowed a bit, and I'm down about another 5 lbs. I'll be starting the 5 mg tomorrow. 16 lbs in my first month is pretty darn good, I'd say. Very little side effects thus far: severe nausea, but it's fleeting; it sticks around for 30-60 seconds then disappears, occurring every two or three days. In terms of how I feel, the changes have been subtle but definitely noticeable. My appetite is absolutely gone for the first 48 hours after injection, then comes back gradually. By the 5th or 6th day, I'm thinking about food again on a regular basis. I do feel that I have more energy, and my willingness to do even small household tasks seems to be higher than it has in a couple of years. Everything just seems like less of a burden. I started at 441 lbs, and am hopeful I can get back to around 300 eventually."

• ali...
• Taken for 1 to 6 months
• April 29, 2024

"Started at the end of Jan 24. 4 weeks at 2.5mg, 8 weeks at 5mg due to lack of supply. I've had to seek alternatives due to the shortage of this drug, but it is worth it. I've lost 30 pounds in 14 weeks and moved up to 7.5mg on my last dose. The food noise is gone. The alcohol noise is gone. Other than some nausea and fatigue on shot day, side effects have been mild and easily manageable. I wish I'd have been able to start this long ago and gotten my life back. 30 pounds to go and I have no doubt I will be successful."

• Anonymous
• Taken for 1 to 6 months
• March 29, 2023

"I'm on month three. My doctor thinks I might be too sensitive to it and may have to stop soon. Extreme nausea, occasional vomiting, and sulfur burps followed by diarrhea, weakness, and lethargy. The pros: in three months, I've gone from 262 lbs to 239 lbs."

• Sus...
• Taken for 1 to 6 months
• June 24, 2024

"I’ve used Zepbound for almost 5 months & have lost 15 lbs. I experienced diarrhea at the beginning but much less now. What I didn’t expect was that my bladder issues like leaking, etc. would stop. It has been amazing! I went from needing valve & bladder surgeries to complete stoppage. I hope this info will help other women with their urology issues. Even if I never lost another pound, if another Zepbound side effect helps my bladder, I’m in!!"

• Lil...
• Taken for less than 1 month
• March 26, 2023

"I have been on Mounjaro for just two weeks. I've lost 5 pounds without trying. While that's nice, I am posting a very early review to let other newbies know that other than some indigestion the first two days, I haven't had any side effects. I had major constipation on Ozempic. I find taking a daily stool softener, staying hydrated, taking a Metamucil tablet daily, and taking a daily prebiotic (get the refrigerated one in your pharmacy as it has live cultures. Keep it refrigerated!). I'm on 5 mg, but I am moving up to 7.5 next week. I will go to 10 mg if there is no supply of 7.5. My pharmacist said to get my order for the 7.5 mg in at least 7 days early so they can get it in on time. They don't stock it, but they get it overnight. Just FYI, after using Ozempic and Mounjaro, I weigh less than I did 10 years ago. I've gone down 4 sizes and 4 inches off my waist since Christmas! Now a petite XL rapidly headed to petite L."

• Sar...
• Taken for less than 1 month
• February 28, 2025

"I started Mounjaro four days ago. Have lost 7.7 lbs!! Absolutely delighted with it. Zero side effects. Feel fuller for longer. Please remember to drink water/fluids on it as you forget with the feeling of fullness!"

• Dia...
• Taken for 6 months to 1 year
• November 8, 2024

"When I started out on the lowest dosage, everything went great. I have lost 40 pounds and have been pleased. I requested from my doctor to up my dosage to 5 mg. Now I have an allergic reaction, mostly on my face. Red, splotchy, hot marks all over my face. Have there been any other patients that have experienced the same reaction?"

• Anonymous
• Taken for 2 to 5 years
• March 26, 2025

"This medication saved my life! In the beginning, the nausea was very noticeable but worth every bit! I never really had a problem with my weight until after my pregnancies. I gained over 90 lbs with each of my two pregnancies. Being at over 300 lbs and only 5’1” was a miserable existence. I couldn’t breathe and was exhausted all of the time, not to mention pre-diabetic and very high blood pressure. It has definitely been a journey, but I stand by that this medication saved my life. I’ve lost 125 lbs. I still have a way to go to get to my goal, but I’m so happy to be alive to see how much better life can be! By the way, my A1C is now normal, and the hypertension has also resolved! I’m very grateful!"

• Amb...
• Taken for 1 to 6 months
• February 23, 2024

"I am 5'2", 41 years old, started taking the shot in November of 2023. Weighed in at 293, cried all the way home. Within a week lost 16 pounds. Here I am, almost a complete 4 months later, and down 72 pounds. Best thing I have ever done. No more snoring or waking up all hours of the night, and I have so much more energy. Yes, I have some constipation, but it is a small price to pay to feel so much better! Next month I will be on the highest dose. So, from here on out, it's up to me to keep it moving with healthy activity and diet."

• Anonymous
• Taken for 1 to 6 months
• February 26, 2024

"So far, so good. Rarely get hungry and can't eat too much. Side effects: Heartburn, reflux, constipation, hair loss. I will have to weigh myself in the morning, but I am guessing I am down about 8 lbs. in 5 weeks. Just started on the 5 ml. No exercise yet. Wine and alcohol will definitely slow down the progress. Not a lot of cravings for junk. Every now and then I want something fried, but it will have you on the crapper by the next morning! Stay away from greasy food on this! And YES, the needle DOES hurt to me!"

• Can...
• Taken for 1 to 6 months
• April 18, 2024

"I am in my 50s and I stayed on the 2.5 for 2 months and just began the 5 mg today. I had gastric sleeve exactly a year before covid, lucky me, huh? Working from home, no gym, already had depression, joint, and severe back issues. It all did not mix with slowing down and sitting down. I gained half of the weight I lost, and the high cholesterol returned. I started Zepbound on Feb 17, 2024, and lost 18 lbs by my first check-up on April 1. Very fast. My cholesterol dropped significantly. I do not have high blood pressure, but it was down too. All blood work is great. The only side effect is constipation that I fixed with Miralax. There are no food cravings or noise in my head. I get full very fast, although I have to remind myself to eat. I have dry mouth, I bought sugar-free popsicles to deal with that. I have been sleeping better, although I stay up late due to the energy it gives me."

• Ano...
• Taken for 1 to 6 months
• April 29, 2025

"My wife has been taking it since January this year and has lost just a hair over 50 lbs. It has done very well for her and the weight is staying off. The only side effects noticed so far are that it makes you very gassy, somewhat indigestion, and every now and then a little constipation."

• gle...
• Taken for 1 to 2 years
• April 29, 2025

"I am 56 years old and I weighed 343 lbs, and my height is 6 ft. tall when I asked my doctor about using Mounjaro. I was a type 2 diabetic. I wore a size 50 pants and a 4 XL shirt. Started Mounjaro a year and six months ago along with a low carb diet. I walked on the treadmill 1 to 3 miles 3 times a week. As of today, I've lost 134 lbs and wear a size 32 to 34 pants. My shirts are large to extra large. I am able to jog and not walk. My A1c is 4.5 to 5.4, down from 7. All around better quality of life thanks to Mounjaro. I wished there was a way to post my pictures of my before and after on here. But I just wanted to share, and if my 56-year-old self can do it, anyone can. God bless."

• R S...
• Taken for 6 months to 1 year
• December 31, 2024

"I've been on Zepbound for 6 months, and it has worked great for me! 40 lbs. down!!! I only feel yucky the day after the injection, but other than that, no other concerns. I just received a letter from my insurance company (Keystone East) stating that beginning 1/1/2025, IBX in whole is no longer covering weight loss drugs. WOW!!!! :( People like myself have been waiting most of their lives for a drug like this, and here we go with corporate America. Even though I'm 40 lbs. down, I still need to lose an additional 40 lbs. just to be considered overweight and not obese in the medical world. My joints no longer hurt, and I can work out without the aches and pains. My overall health has improved so much, and I am greatly disappointed and upset with this decision from IBX. I wish everyone much luck if this will be happening to you too after the new year."

• Lin...
• Taken for 1 to 6 months
• December 5, 2024

"I started taking Zepbound on the first of September, am 5'8, was weighing 190. I stopped taking Zepbound on November 18th, had no serious side effects, I was just feeling moody. Stopped at my goal of 175.9 and still losing on my own. It's December 5, and I weigh 172.9. Zepbound has taught me to eat a balanced, healthy meal without all the cravings, portion size, and exercise. Down 16 pounds."

• BK...
• Taken for 1 to 6 months
• April 5, 2025

"I started this journey at 387 lbs. On the initial dosage of 2.5 mg, I lost 12 lbs in the first month. I have no side effects to speak of, and the food noise is 90% gone - although it seems to know when I'm within 24 hours of my next injection. The weight loss from the 5 mg cycle feels like another 10 lbs, but my Dr. visit will tell the tale. I am VERY happy with this decision, and I have NO regrets."

• foo...
• Taken for 1 to 6 months
• July 22, 2024

"I've been on this medication for 6 weeks and have never felt better about my body or my day. I didn't realize I could have a day where I wasn't thinking about food from the minute I got up until I fell asleep at night. I feel free to think about other things and to not be distracted by trying to have willpower to not eat. It's a huge relief. Is this what thin people feel like? People who have never struggled with being overweight? I have always thought my weight was based on my genetics, and maybe it is-but it's also my brain that literally is addicted to food. It feels like I've been released from an addiction. I haven't noticed any side effects. I tried Ozempic before this and was very constipated and had stomach issues. I don't feel that way at all on Zepbound, my stomach is fine. I'm on 2.5, it's very easy to administer, and I feel like it really works. I hope I'm able to take it for a long time, I'm sort of afraid to go back to the brain I had before taking it."

• Vic...
• Taken for 6 months to 1 year
• December 4, 2023

"I have been diabetic and overweight for 20 or more years, along with several health issues and various medications. Thank God for my doctor and Mounjaro. I started at 2.5 and 204 lbs in March, with few side effects. It is easy to use. I am now on 5.0 and 64 lbs lighter, and my A1c is at 5.7. I can breathe better and go for walks more. I crave no sugar or carbs. I was miserable with no hope in sight. I will be going on the 7.5 with hopefully no side effects. Thank you Mounjaro and my doctor for giving me my life back."

• Day...
• Taken for 1 to 6 months
• September 14, 2024

"Have been injecting Mounjaro weekly for a month now and have lost 4 kg, but here is what I learned… 1. Make sure you're fully hydrated before injecting the recommended dosage of the first 2 weeks, needles being 2.5 ml, as it dehydrates you big time and most of the time is why you are feeling nauseated, but keep hydrated, drink up. Eg. Powerade or Hydralytes… 2. Inject in the top thigh as it is less nausea feelings than injecting in the tummy. 3. Your body automatically tells you that you are full after a small portion of dinner (saucer plate size) as breakfast I craved Vegemite on thin bread, so maybe I was lacking either salt or B12 levels down. Lunch I ate a small amount too, but have snacks 4 times a day, even one sugar lolly made me feel better."

• Min...
• Taken for 1 to 2 years
• November 29, 2023

"I am a 61-year-old female. I have been overweight for over 20 years and also dealing with other health issues. I started taking Mounjaro just a little over a year. I started with 5mg in the first week and lost 9lbs in one week, then I increased to 7mg and continued to lose weight. Long story short, I am now on 15mg and I have lost a total of 90lbs, from 339 to 247. This is unbelievable. I too have to make myself eat, like other reviews have stated. I feel so good. I have had 3 major back surgeries within the past 3 years. My A1C was never good, but now it's perfect. I used to walk hunched over, and now my posture is perfect. I want to lose 50lbs or more but I am happy with the state I'm in. However, I will be extremely happy to lose some more weight. I am a living testament that these injections work, just like the thousands of other reviews are saying. Where was this medication 20 years ago?"

• Sho...
• Taken for 1 to 6 months
• April 25, 2023

"This medication is incredible. My cholesterol and blood pressure were borderline. My doctor suggested losing weight (I have had a weight problem my entire life), which was an ongoing life pursuit for me. Nothing lasted. I would end up feeling worthless and depressed. I started this medication in January 2023. Today is April 25th, and I have lost 36 pounds. My blood pressure is on its way down. My energy levels were stable throughout the day from week one, so it is not just the weight loss, the medicine has helped with my ADHD and my depression. The only side effect I have experienced was constipation, which I corrected by using small dosages of Miralax daily. I hope the FDA approves this medication for weight loss soon. It is a great tool to use along with healthy eating and exercise."

• Tra...
• Taken for 1 to 6 months
• August 19, 2023

"I am just starting week 5. I started on 5mg, so today was my first 7.5. Last month, I lost exactly 20 pounds. I started at 222 and now I'm at 202 after 1 month. I get bad constipation, but nothing Dulcolax liquid can't fix. I drink 2 protein shakes a day, a handful of chicken, and some days I replace chicken with fruits and low-fat cottage cheese. I drink lots of water and have 1 coffee with only milk once a week. I can't wait until this time next month. It's definitely a game changer. I haven't been that active, but today I will start going to the gym 5 days a week. I will update next month."

• Ano...
• Taken for less than 1 month
• January 16, 2025

"I started 2.5 on 1/12/25. I haven't had any side effects. What I have noticed is the reduction in my need to snack. I was always wanting something after dinner. One snack turned into 2 or 3. I don't feel that way anymore. Sometimes I feel that I don't want to eat what's in front of me at mealtimes, but I am trying very hard to eat and keep protein up. I lift heavy weights 4 days a week, and I want to retain muscle if this ends up helping me finally lose the weight I've been burdened with for my entire life. I did get a bruise at the injection site. I can't wait to weigh myself to see if I've lost. So far, feeling great!"

• Mil...
• Taken for 6 months to 1 year
• December 1, 2024

"I started Zepbound in April 2024 at 193 lbs. It’s December 2024, I’m now 140 lbs. I have stayed at the 10 mg dose for almost 3 months now, as I am trying to tone my body since I lost 50 lbs fast. The side effects suck when I go up a dose, but my body adjusts after 4 weeks, so it’s been great. I have noticed that I wake up with hunger pains now, but my plan is to get used to them again before I start weaning off the drug. Side effects for me include headaches and fatigue. It’s not that bad after a while, the main thing is being strategic and proactive about getting your fiber, protein, and water in. I haven’t been to the gym since I started the 10 mg, and I’ve slowed down on the weight loss (which I’m okay with). I like 140, I’m just trying to tone now, so when I wean off, it won’t all come back. I’ll update you guys in a couple of months."