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Tirzepatide for Weight Loss (Obesity/Overweight) User Reviews (Page 3)

Brand names: Mounjaro, Zepbound

Tirzepatide has an average rating of 8.9 out of 10 from a total of 398 reviews for the treatment of Weight Loss (Obesity/Overweight). 84% of reviewers reported a positive experience, while 4% reported a negative experience.

Reviews for Tirzepatide

  • Mike...
  • Taken for 1 to 6 months
  • January 15, 2024

Zepbound (tirzepatide) "I’m an 6’4, 275 male, 62 years old - no diabetes or health issues, on no other meds. Obtained prescription via Dr and took first 2.5mg injection on Dec. 24. Lost 10 pounds with the first 3 shots, then Dr said I could go to 5mg (saved the last 2.5mg pen for future use) because weight loss had stopped. After starting mg, lost 2 pounds in 2 days - so combined weight loss using 2.5/5mg is now at 12 pounds in e weeks! No significant/terrible side effects except some constipation, intermittent fatigue, and minor chills at times (not a lot - could just be the cold weather). Ive yo-yoed up and down with weight for years. Because of my size, I can eat a lot of food - but this drug has significantly reduced my appetite and I have more energy overall. I can’t wait to see the results in a few more months. Zepbound has so far been perfect for me. I don’t mind the $550 price (with the Lilly savings card - has been hard to get CVS to make it work but that’s another story/nightmare)."

10 / 10
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  • Mike
  • Taken for 1 to 6 months
  • March 5, 2024

Zepbound (tirzepatide) "Been on Zepbound 7 weeks now. Lost about 22 lbs so far with no exercise. This stuff is amazing at curbing your appetite. But beware, stick to healthy foods and minimal portions because the nausea is otherworldly. I ate too much too late in the day yesterday. I had to leave work early today for the second time since being on this med. Light-headed, profuse sweating, chills, diarrhea almost non-stop and even puking. This med is a miracle, but you cannot mess around. Take it seriously. Cut back portions, minimal dairy, low sugar and don't eat too late. I'm excited to see how far I can go on this med. So thankful I have access."

10 / 10
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  • Mark
  • Taken for 1 to 6 months
  • May 25, 2024

Zepbound (tirzepatide) "Started using Zepbound in March 2024, at 2.5 mg. History of Obesity (BMI > 29) and Hypertension. Starting weight was 202 lb. and Blood Pressure Avg. of 153/90. As of today, May 24, 2024, currently on 10mg. My weight is currently 177 lb, having lost 25 lbs (12%) of starting weight. It was easy to learn how to use the injection pen, and it is a painless process. I am also exercising, running 4-5 days per week and weight training 2 days per week. Exercise is an important adjunct to weight loss treatment, and can help maintain muscle mass while losing weight. It is also imperative to eat foods rich in protein and green, leafy vegetables. Side effects have been minimal, with occasional constipation, which is remedied by using Miralax or similar products."

10 / 10
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Frequently asked questions

  • Anonymous
  • Taken for 1 to 6 months
  • January 3, 2024

Mounjaro (tirzepatide) "I'm a 53-year-old male and my weight has gone up slowly with each passing year, so the ladies at my doctor's office were telling me how they all were losing weight by taking the Mounjaro shots. I was a little bit worried at first because of the thought of having to give myself a shot. I barely felt it, so I started out on the 2.5 shots, and the only side effect I got was the burping sulfur taste. This is the absolute best thing I could have done; it's lowered my blood pressure, and I'm off the meds for that. I sleep better and feel healthier, the only bad thing is my clothes don't fit. I'm feeling better about myself. I'm now on the 10mgs, but each month I went up to a stronger dose, but I'm going to stay with the 10s as a maintenance shot. I don't feel hungry at all; I have no cravings, I have to make myself eat, and when I do eat, it's just a little bit at a time. You don't want to overeat on this or you will be sorry. I highly recommend it. A big thanks to the makers of Mounjaro. I've lost 40 pounds in 4 months."

10 / 10
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  • ali
  • Taken for 1 to 6 months
  • April 29, 2024

Zepbound (tirzepatide) "Started at the end of Jan 24. 4 weeks at 2.5mg, 8 weeks at 5mg due to lack of supply. I've had to seek alternatives due to the shortage of this drug, but it is worth it. I've lost 30 pounds in 14 weeks and moved up to 7.5mg on my last dose. The food noise is gone. The alcohol noise is gone. Other than some nausea and fatigue on shot day, side effects have been mild and easily manageable. I wish I'd have been able to start this long ago and gotten my life back. 30 pounds to go and I have no doubt I will be successful."

10 / 10
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Are you taking this medicine?

  • Andrea
  • Taken for 1 to 6 months
  • June 8, 2024

Zepbound (tirzepatide) "Started out great. Moved to 5.0 and had AWFUL vomiting on day 3 after injection. Dr. tried to move me back to 2.5 but Rx store was unable to get it. Went 5 weeks before it was restocked. Started 2.5 again with 0 effect. And I mean zero. Moved to 5.0 and the nausea is there, but so far, no vomiting. What concerns me is that I have suddenly been struggling with an elevated pulse and higher than normal BP. Wasn't an issue before, so not sure if it's related or incidental. May stop it because I just don't feel good. In addition over the 5 months of on and off again, I am down 4 pounds...and following a reasonable diet plan. Discouraged."

5 / 10
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  • Anonymous
  • Taken for 1 to 6 months
  • February 26, 2024

Zepbound (tirzepatide) "So far, so good. Rarely get hungry and can't eat too much. Side effects: Heartburn, reflux, constipation, hair loss. I will have to weigh myself in the morning, but I am guessing I am down about 8 lbs. in 5 weeks. Just started on the 5 ml. No exercise yet. Wine and alcohol will definitely slow down the progress. Not a lot of cravings for junk. Every now and then I want something fried, but it will have you on the crapper by the next morning! Stay away from greasy food on this! And YES, the needle DOES hurt to me!"

8 / 10
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More FAQ

  • baechr
  • Taken for 1 to 6 months
  • March 18, 2024

Zepbound (tirzepatide) "Absolutely life-changing. For the first time in my life, I'm satisfied by reasonable portions. I'm not always thinking about the next thing that I'll be eating. I'm able to feel and respond to my actual hunger cues without my scarcity brain taking over. Even if I wasn't losing weight, the relief of food obsession and binge eating disorder would be worth it. Four weeks in, down 13 lbs and very satisfied. Only side effect has been feeling cold and some mild constipation."

10 / 10
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  • Jean
  • Taken for 6 months to 1 year
  • June 25, 2023

Mounjaro (tirzepatide) "I have never had anything like this in my life! I was always small and IBW until I went through menopause. Afterwards, I gained weight regardless of what I did. Nothing I tried, and no program I did helped. Once I reached a size 22 on my 5'4 frame and weighed almost 230 lb, I decided to do something else. By this time, I had also become "pre-diabetic" and was insulin resistant. I have been on Mounjario for 7 months and am now a size 8, down 65 pounds. My blood sugars are perfect, and I feel like my old self again! The journey has been effortless, and I enjoy the foods I like, but my body metabolizes it better. I have now switched to Wegovy since insurance only covers Mounjaro if you are a diabetic. I would stay on it forever, but cannot continue to pay almost $1100.00/month for it."

10 / 10
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  • chris...
  • Taken for 1 to 2 years
  • September 15, 2023

Mounjaro (tirzepatide) "This medication has given me my life back. I have been on the diet and workout train for the last 24 years, but nothing worked to lose a significant amount of weight. I did take one medication that worked temporarily years ago but left me feeling like trash, and once I was finished, the weight came back and then some. I have lost 90 lbs on Mounjaro over the last 14 months. Yes, my eating did improve because it quieted the food noise. I no longer starve myself throughout the day and then binge. Mounjaro has truly changed my life. I was giving up hope and falling into depression because nothing worked, and I didn't want to risk my life with surgery. Thank you to the makers of this medication. You have no idea how you are changing people with weight loss struggles. It's so much bigger than stop eating and working out more. I wish people would understand, and I wish insurance would approve this for weight loss. So many people are struggling. I never got real sick, sometimes a little nausea the day after."

10 / 10
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  • disap...
  • Taken for 1 to 6 months
  • April 1, 2024

Zepbound (tirzepatide) "After so many people I knew were doing so well on these injections, I started Zepbound 6 weeks ago. I was fine for 24 hours, then the side effects kicked in. I don't recall ever feeling this sick. Sulfur burps, churning stomach, started vomiting and diarrhea for 3 full days. I was sick for days after the first shot. I had no hunger while so very sick. Week 2 and 3 had no problems and the food cravings were gone. I was prepared to be very successful on this medication. Week 4 sulfur burps came back again, 24 hours after my injection. The same reactions returned but less violent; I was sick for 24 hours. Maybe a fluke? Week 5 and 24 hours in, same sulfur burps started it again: diarrhea, stomach spasms, and vomiting. Nope, off the Zepbound. I would rather stay fat than make myself sick with every dose. I never got beyond 2.5. I know this has been wonderful for some people; it's just not for me."

8 / 10
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  • Anonymous
  • Taken for less than 1 month
  • March 24, 2024

Zepbound (tirzepatide) "Ten days on Zepbound. Love this medication. The energy it gives you is amazing. 1st day injection in thigh developed bruise and slight nausea and headache. But no biggie. 2nd shot belly super easy. Takes away urge to eat. No more stomach grumbling when hungry either. I have a protein shake in the morning, mid-morning protein bar, little bites throughout the morning. Small lunch and salmon or chicken for dinner. Veggies and fruit are important. No issue with bathroom. I take a fiber gummy and multivitamin daily. Treadmill and gym. After showering, I've been using lots of lotion on skin, massaging in. You'll be fine. Smart choices in foods. Yogurt gave me nausea as did tuna with mayonnaise. 6 lbs so far."

10 / 10
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  • Amber
  • Taken for 1 to 6 months
  • April 27, 2023

Mounjaro (tirzepatide) "I was on Mounjaro for 3 months for weight loss, starting weight 180 lbs. I Increased to the next dosage every month. I had minimal side effects besides constipation and lost a total of 28 lbs. I did not wing off the medication and everything went fine, did blood work last week and everything was perfect compared to the year before. My weight has been steady thanks to the healthy habits I built during the medication."

10 / 10
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  • Illin...
  • Taken for 1 to 6 months
  • February 14, 2024

Zepbound (tirzepatide) "I have been on Zepbound for 6 weeks. (4 weeks 2.5) (2 weeks at 5.0) I have lost 23 lbs. 307-284 I ride bike/treadmill and lift weights. I eat 2300 calories a day. If I happen to eat too much, I don't seem to notice. But what I do notice is I don't crave food like before. Before, I used to still be hungry after dinner. Not anymore. That part of my brain that was ravenous for more is gone."

10 / 10
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  • KKD
  • Taken for less than 1 month
  • March 25, 2024

Mounjaro (tirzepatide) "I am just starting this process. It has been 2 1/2 weeks on 2.5 ml. I have lost 9 lbs. I'm 55 years old, 5'7", 182 starting weight. Menopause kicked my butt; I could never lose more than 5 lbs. Negative side effects: headaches (which I've been prone to or sensitive to in the past), sometimes several times a day. I had mild diarrhea the first week and am now one week in with constipation. Mounjaro seemed to reduce my internal stomach size enormously. I don't have to remind myself to eat, like other people have said, but my body is on a delay and feels full 90 percent of the time - like I don't wake up ready for breakfast; it takes two hours to want to eat. What I do eat is a fraction of what I used to eat. For example, a small soup is plenty for lunch, yogurt for breakfast. It's definitely working for me, very happy. Good luck to everyone trying this:)"

10 / 10
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  • Vick
  • Taken for 6 months to 1 year
  • December 4, 2023

Mounjaro (tirzepatide) "I have been diabetic and overweight for 20 or more years, along with several health issues and various medications. Thank God for my doctor and Mounjaro. I started at 2.5 and 204 lbs in March, with few side effects. It is easy to use. I am now on 5.0 and 64 lbs lighter, and my A1c is at 5.7. I can breathe better and go for walks more. I crave no sugar or carbs. I was miserable with no hope in sight. I will be going on the 7.5 with hopefully no side effects. Thank you Mounjaro and my doctor for giving me my life back."

10 / 10
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  • AmberO
  • Taken for 1 to 6 months
  • February 23, 2024

Mounjaro (tirzepatide) "I am 5'2", 41 years old, started taking the shot in November of 2023. Weighed in at 293, cried all the way home. Within a week lost 16 pounds. Here I am, almost a complete 4 months later, and down 72 pounds. Best thing I have ever done. No more snoring or waking up all hours of the night, and I have so much more energy. Yes, I have some constipation, but it is a small price to pay to feel so much better! Next month I will be on the highest dose. So, from here on out, it's up to me to keep it moving with healthy activity and diet."

10 / 10
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  • Anonymous
  • Taken for 1 to 6 months
  • March 29, 2023

Mounjaro (tirzepatide) "I'm on month three. My doctor thinks I might be too sensitive to it and may have to stop soon. Extreme nausea, occasional vomiting, and sulfur burps followed by diarrhea, weakness, and lethargy. The pros: in three months I've gone from 262 lbs to 239 lbs."

7 / 10
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57 Report
  • Lilly
  • Taken for less than 1 month
  • March 26, 2023

Mounjaro (tirzepatide) "I have been on Mounjaro for just two weeks. I've lost 5 pounds without trying. While that's nice, I am posting a very early review to let other newbies know that other than some indigestion the first two days I haven't had any side effects. I had major constipation on Ozempic. I find taking a : daily stool softener, stay hydrated, take a Metamucil tablet daily, and take a daily prebiotic (get the refrigerated one in your pharmacy as it has live cultures. Keep it refrigerated!) I'm on 5mg, but, moving up to 7.5 next week. Will go to 10mg if no supply of 7.5. My pharmacist said to get my order for the 7.5mg in at least 7 days early so they can get it in on time. They don't stock it, but, get it on overnight. Just FYI, after using Ozempic and Mounjaro, I weigh less than I did 10 years ago. I've gone down 4 sizes. 4 inches off my waist since Christmas! Now a petite XL rapidly headed to petite L."

10 / 10
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  • Tpott
  • Taken for 1 to 6 months
  • March 3, 2024

Zepbound (tirzepatide) "50-year-old female with 100 lbs to lose and PCOS. Been on Zepbound for 6 weeks (just took 7th shot). Minimal side effects. Occasional nausea, headaches, and sore muscles, usually the day after injection, but they go away by the next day. Taking the 5 mg dose right now. I have been getting large injection site rashes with itching, burning, and swelling with the last 3 doses. The swelling and itching go down after 3-4 days, but the red spots are still visible from all 3 of the previous doses. I didn't get this with the 2.5mg dose at all. Hoping it was just this last box of the medicine and the next will be better. I have only lost 5 lbs in the 6 weeks I have been on it, which has been very disappointing. It has lowered my blood pressure though. It was on the high side of normal before, now it's perfect. Really hoping that going up to the 7.5mg dose will start having better results for me as I have got a long way to go, and hopefully the skin reactions won't get worse."

7 / 10
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  • Minis...
  • Taken for 1 to 2 years
  • November 29, 2023

Mounjaro (tirzepatide) "I am a 61-year-old female. I have been overweight for over 20 years and also dealing with other health issues. I started taking Mounjaro just a little over a year. I started with 5mg in the first week and lost 9lbs in one week, then I increased to 7mg and continued to lose weight. Long story short, I am now on 15mg and I have lost a total of 90lbs, from 339 to 247. This is unbelievable. I too have to make myself eat, like other reviews have stated. I feel so good. I have had 3 major back surgeries within the past 3 years. My A1C was never good, but now it's perfect. I used to walk hunched over, and now my posture is perfect. I want to lose 50lbs or more but I am happy with the state I'm in. However, I will be extremely happy to lose some more weight. I am a living testament that these injections work, just like the thousands of other reviews are saying. Where was this medication 20 years ago?"

10 / 10
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  • Dawn
  • Taken for less than 1 month
  • March 18, 2024

Zepbound (tirzepatide) "Started Zepbound 2.5 mg just 3 days ago. For the first time in my LIFE, I am eating to nourish my body, and not to satisfy hunger or cravings! Super excited to see how the weight will drop with new habits. Downside, I wasted a pen the very first time I injected because I didn't remove the grey closure. My fault for not thoroughly following the instructions but total bummer because the cost of this med is not cheap and the pharmacy says they can't fill an Rx for just one pen. It would be nice if the manufacturer of the drug would allow a single pen to be purchased for a lesser cost."

8 / 10
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  • sherri
  • Taken for 1 to 6 months
  • March 18, 2024

Zepbound (tirzepatide) "I have been on Zepbound for two months and have lost only 9 pounds. I don't eat breakfast because I am not hungry; this has been a lifelong habit of mine. I am hungry at noon and eat more than I should. I have found that I am eating too fast, which is causing me to not have the weight loss that I would have if I ate slower. I have noticed that when I eat slower, I stop eating when I am halfway done with my meal. Hopefully, I can break a lifelong habit of eating fast. I have no side effects from the drug or overeating."

4 / 10
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  • mjeff...
  • Taken for 1 to 6 months
  • May 9, 2024

Zepbound (tirzepatide) "I originally started the Zepbound shot at the end of this past January. I weighed a total of 202 lbs when I started it. That would be about 3-4 months ago. I was very self-conscious, I didn't want to take any pictures of myself, I felt disgusted by myself, I always brought myself down, etc. But now, now I weigh 154 lbs. I'm at the 10 mg of the Zepbound. I started off as the lowest and I'm still not at the highest, to be honest. I lost about 50 pounds in the last 4 months! I researched it and it'll take 16 months to lose about 50 pounds for a normal person who doesn't take anything. And I did it in 4 months with that shot! I never thought I would get to this weight, to be honest. In the beginning, I was going to the YMCA to work out every week to put in the extra work, etc. At first, I started losing like a pound a day, not even kidding, sometimes 2 lbs a day. Then it went to a pound every couple days, and it would vary."

10 / 10
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  • Jovanna
  • Taken for less than 1 month
  • March 22, 2023

Mounjaro (tirzepatide) "So far, it's been great, no side effect whatsoever. I could say I'm not hungry at all, I eat out of habit but very little amount of food. Since I'm not hungry it allows me to make better food selections."

10 / 10
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50 Report

Reviews may be edited to correct grammar/spelling or to remove inappropriate language and content. Reviews that appear to be created by parties with a vested interest are not published. This information is not intended to endorse any particular medication. While these reviews may be helpful, they are not a substitute for the expertise, knowledge, and judgement of healthcare professionals.