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Aubagio and Fatigue: What Users Say

Fatigue: mentioned by 7 users (8.1%)

Based on user experiences from 86 Aubagio reviews, the following table shows the most commonly mentioned side effects.

All user comments are moderated by Drugs.com. Each review is verified for relevance and screened for inappropriate content. Side effects are user-reported and not clinically verified.

hair loss 41.9%
headaches 14.0%
depression 8.1%
fatigue 8.1%
upset stomach 8.1%
diarrhea 7.0%
nausea 7.0%
blurred vision 5.8%
nerve pain 5.8%
tiredness 5.8%

Reviews for Aubagio

Commonly mentioned side effects
  • Dob...
  • Taken for 1 to 6 months
  • January 26, 2018

For Multiple Sclerosis "Diagnosed 3 years ago - now know that I've had MS for 30 years. Stopped Copaxone due to awful injection site reactions, then after playing the insurance game, started Aubagio 3 months ago. The side effects of these medications are worse than the disease!! I stopped taking it a week ago due to horrific muscle/joint pain, daily pounding headaches, blurry vision, diarrhea, ear congestion, neuropathy in hands/feet, and extreme fatigue. I'm supposed to call my Dr in 2 weeks to discuss how I feel after 3 weeks off. Seriously, these meds that are designed to help are poison! I'm going to stay off the 'preventives' and continue my clean eating and aquatic exercise."

1 / 10
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70 Report
  • Sha...
  • Taken for less than 1 month
  • June 14, 2018

For Multiple Sclerosis "I was diagnosed with MS in 2008, late in life at the age of 48. I started on Copaxone and was on it until a few months ago. I only wanted to change as I was running out of injection sites. I started Aubagio 2 days ago. This is an awful drug!!!!! The side effects far outweigh the benefits, and I'm only 2 days in!!! Headache, heart palpitations, numbness everywhere, pain everywhere. Scattered thoughts, a feeling of heaviness throughout my body, fatigue...it's HORRIBLE!!! I WILL not take another pill."

1 / 10
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63 Report
  • poo...
  • Taken for 1 to 6 months
  • October 10, 2018

For Multiple Sclerosis "I've had MS for 18 years and have been taking Aubagio for 6 months-my first treatment. My MS was active and I had developed multiple new lesions with relapses. The first 3 months were rough, with nausea, diarrhea, sleep disturbances, fatigue, and an overall 'sick, flu-like' feeling. I stuck with it because the alternative is much worse. My hair has thinned, but I anticipated that side effect. I have a runny nose most of the time and still have some diarrhea. I've had 2 relapses, but they were only a few days in length. I am awaiting an MRI to determine if the Aubagio is working, so fingers crossed. I want to stay on it as Copaxone is the next option. My insurance doesn't cover Aubagio, but I qualified for a bridging program, so I am forever grateful. Stick with it if you can tolerate the side effects for a couple of months and your neuro approves. Hopefully, they will subside for you as well. Good luck to everyone managing this disease."

7 / 10
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42 Report

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Frequently asked questions

  • Me2...
  • Taken for 6 months to 1 year
  • December 25, 2019

For Multiple Sclerosis "Have been on Aubagio for 6 months now. I had some hair loss, noticeable only to me. Absolutely no other side effects, feeling great, I get my days of fatigue if I do too much, but I generally feel good!"

10 / 10
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20 Report
  • Sof...
  • Taken for 2 to 5 years
  • February 9, 2020

For Multiple Sclerosis "I have been diagnosed with MS in 2004, and I haven't taken any medication until 2018, when I started on Tecfidera, and it was horrible. I had all the side effects and felt I wasn't living a whole month. The doctor decided that I try Gilenya, but that didn't work for me since my heartbeat was too low to be on it. Then I started on Aubagio and was on it for two years. At the beginning, I had hair thinning and loss, sometimes I have heavy legs, weakness, and fatigue. My vision is sometimes not clear, especially if I am stressed on that day. Recently, the doctor asked me to stop it since I started having bruises all over my body, and from my blood work, I have a bleeding disorder caused by the medication and alopecia. I am having my MRI tomorrow and will decide what to be on. As someone said, we are just poisoning ourselves."

1 / 10
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16 Report

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  • Bel...
  • Taken for 1 to 2 years
  • January 10, 2021

For Multiple Sclerosis "I got diagnosed with MS in 2018. Haven't got any new 'spots.' What I now have come to recognize as attacks is pain and hurt I've dealt with for many years. So I guess I've had MS a long time before I got diagnosed with it. I'm on Aubagio and gotten lazy, tired, angry, sad, clumsy as anything! It's like everything about my personality has gotten heightened by 100. I used to run half marathons, lift weights, walk, and run in the mountains. That's not happening now. I thought it was because of the MS, but now, after reading these reviews, I'm starting to think the Aubagio is to blame...."

4 / 10
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12 Report
  • Anonymous
  • Taken for 1 to 6 months
  • January 3, 2018

For Multiple Sclerosis "6 weeks in, mostly gastric issues, abdominal pain. Hand and arm tingling. First blood test revealed slightly increased ALT. General feeling of fatigue."

7 / 10
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28 Report

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Reviews may be edited to correct grammar/spelling or remove inappropriate content. Reviews appearing to come from parties with a vested interest are not published. This information is not intended to endorse any medication and should not replace the expertise and judgment of healthcare professionals.