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Sulfamethoxazole / trimethoprim for Bacterial Skin Infection User Reviews (Page 4)

Brand names: Bactrim, Bactrim DS, Septra, SMZ-TMP DS, Co-trimoxazole, Septra DS, Bactrim IV, Bactrim Pediatric, Sulfatrim Pediatric Bethaprim Bethaprim Pediatric …show all brand names

Sulfamethoxazole / trimethoprim has an average rating of 5.1 out of 10 from a total of 247 reviews for the treatment of Bacterial Skin Infection. 34% of reviewers reported a positive experience, while 44% reported a negative experience.

Reviews for Sulfamethoxazole / trimethoprim

  • Cliff...
  • January 13, 2018

Bactrim (sulfamethoxazole / trimethoprim) "Had a very hot and painful boil right on my belt line from shaving my pubic area. Went to the doc and he looked at it and said of the abscess was way too deep to Lance it put me on Bactroban ointment and high dose of Bactrim. After 2 days the infection started to clear up. As far as bactrim side effects not as bad as when I take penicillin mainly really bad headache, extreme thirst, frequent urination. Take probiotics at lunch to help with diarrhea"

8 / 10
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  • Sicker...
  • Taken for less than 1 month
  • October 7, 2020

Bactrim (sulfamethoxazole / trimethoprim) "Had an abcess removed and was prescribed Bactrim. Could not stay awake and got more sick every time I took it. Had most of the symptoms they say to contact your doctor about. Called and was told unless I had a rash there was no reason not to keep taking it. I could not function had an extreme migraine which I have never had before (sensitivity to light and sound). Upset stomach, trouble passing urine, leg pain, chills, fever among others."

1 / 10
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  • Terri...
  • Taken for less than 1 month
  • January 20, 2017

Bactrim DS (sulfamethoxazole / trimethoprim) "I have been taking Bactrim DS for an infection in my toe from a pedicure. It's been 4 days of not feeling human. I'm terribly exhausted. It feels like trying to stay awake after taking NyQuil. After day 2 I started getting bad headaches. I'm only on it for seven days so I'm going to suffer through it but the side effects are almost unbearable."

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Frequently asked questions

  • ilbda...
  • Taken for less than 1 month
  • April 10, 2023

Bactrim (sulfamethoxazole / trimethoprim) "I had a skin infection from some kind of mite that had the symptoms of scabies. I heard Bactrim kills scabies by changing their gut flora. I started taking it, and all the sores alive with whatever was in my skin eating me went dormant and started healing. My skin is clearing up from the infection after just 48 hours. What is confusing is I found mites in my tub that were on my scalp, and they were not scabies, I have to identify them now to figure out how to eliminate them. Bactrim somehow stopped the ones deep in my skin from eating me."

10 / 10
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  • Anony...
  • Taken for less than 1 month
  • August 23, 2019

"I went to my doctor for a boil on my face and another on my lower lip. He prescribed Sulfamethoxazole TMP DS . I started it on a Monday and by Tuesday morning, positive changes started to occur. The boil on my face stopped oozing and the one on my lip stopped growing/being so painful. The good thing was, my doctor prescribed the correct medication and secondly, it started working right away. I took 2 tablets as soon as I got the script from the pharmacy to raise the level of this antibiotic in my bloodstream quickly. Then 1 tablet every 12 hrs of Sulfamethoxazole TMP DS for 10 days. Not many positive reviews of this med on this site, but after taking this for 4 days, my sores continue to heal and look better each day that passes I have zero side effects. No rashes, bumps, insomnia, etc. No idea why others have experienced so many negative effects. I am very pleased w/ this antibiotic."

10 / 10
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Are you taking this medicine?

  • Bex
  • Taken for less than 1 month
  • January 5, 2022

Bactrim (sulfamethoxazole / trimethoprim) "I've taken Bactrim in the past, usually just have gastrointestinal issues. This time, beginning day 3 of 7 I felt like I was hypoglycemic, nervous, jittery, anxious, and like my heart was racing. Day 6 of 7 my resting heart rate was 142, anxiety so bad I was crying. I called the hospital that prescribed it and the nurses spoke to "talked to TWO doctors and NEVER heard of ANYTHING like that" I said "never mind that it's listed under severe side effects right?" I stopped taking it then (Dr said I could keep taking it or stop, it doesn't matter) 24 hours later, I'm back to normal. Resting heart rate is 83. I'll never take Bactrim again."

1 / 10
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  • Adopt...
  • November 13, 2015

Bactrim DS (sulfamethoxazole / trimethoprim) "I was diagnosed with a MRSA Impetigo skin infection and was prescribed the Bactrim DS as well as Bactroban ointment, therefore I cannot know which helped the most, but it did work 95%. I stll have a pink area and the original cut that started this all is still slightly visible. This oral med made me feel horrible. Everyday, after the third day, I was nauseous about an hour after taking it and several times had to take Zofran 8mg which did help. My stomach was a roller coaster and the headaches were really bad. I have Daily Chronic Headache which is daily migraines. But I get C spine nerve ablations which allows me to be 90% migraine free for about 1 year. During the 10 days the migraines came back and with a vengence. Glad to be done."

9 / 10
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  • Anonymous
  • July 9, 2011

Bactrim (sulfamethoxazole / trimethoprim) "I am taking Bactrim for a minor staph infection on my leg. It is going away quickly. I am just experiencing fatigue and headaches. The headaches are probably due to dehydration because I am a runner too. I felt better after I drank more water with the medicine. Also I am experiencing a slight decrease in appetite."

6 / 10
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  • Lano
  • August 22, 2018

Bactrim (sulfamethoxazole / trimethoprim) "I was very hesitant to take this drug after reading the reviews online. Indeed, I was prescribed it for a bacterial skin infection. However, it did little to nothing to eliminate my infection. On day 1 of taking it, I started getting minor headaches. Every time I took a dose after that it made my headache even worse. It just felt like I was putting something harmful in my body. If you're ever in a situation where you are prescribed it (and it's not a life or death situation), tell your doctor no. Do it it for your own body's sake."

1 / 10
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  • Nickerz
  • September 1, 2015

Bactrim DS (sulfamethoxazole / trimethoprim) "Not sure that the medication did much as my abscess burst the night I started the antibiotics. All I know is that by the 3rd and 4th day of antibiotics I was feeling generally unwell, had a headache and awful nausea."

5 / 10
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  • Tinaaa-
  • October 11, 2015

"Worst medicine ever. I'm not allergic to anything by the way. I was prescribed for a uti and had to stop after 5 days. Migraines, eyeballs throbbed, chest was in excruciating pain, neck pain, upper and lower back pain, stomach and ovary pin, and leg pain, especially in the knees, onto of of that, nausea, loss of appetite, dizziness, the immediate and random need to throw up, and worst of all...a red rash all over my body. To top that off, and loss of sex drive. I have never had an allergic reaction to a medicine before...I will never take this again. BEWARE!!!!"

1 / 10
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  • breez...
  • Taken for less than 1 month
  • October 21, 2016

Bactrim (sulfamethoxazole / trimethoprim) "I was just prescribed this antibiotic today due to a staph infection in each leg from shaving. My doctor mentioned MSRA, needless to say I'm freaking out over this. Regardless, it's been about 4 hours since I took the first pill - obviously the infection sites haven't gotten any better, but I'm hoping they do. As far as side effects go, I'm lucky so far to only have a little bit of heartburn and slight nausea/loss of appetite. I'm crossing my fingers this stuff works for me!"

5 / 10
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  • April...
  • Taken for less than 1 month
  • March 14, 2019

Bactrim (sulfamethoxazole / trimethoprim) "My husband was prescribed Bactrim in late April 2009 for what the dr thought was MRSA. Results came back negative and was told to continue taking it. 4-7 days into his antibiotic and his gums bled after brushing his teeth...then his hands turned purple from pushing the lawn mower and under his arms he had petechiae. He was bleeding internally and he had a platelet count of 1,000 (he was very close to death and we didn't know it). The bactrim had caused the low platelet count which means the blood can't clot. He had to have 2 transfusions and then caught Meningitis as well. Bactrim is a very strong antibiotic; use with caution."

1 / 10
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  • lemon...
  • Taken for less than 1 month
  • October 8, 2018

Bactrim (sulfamethoxazole / trimethoprim) "Worst part of this was the size of the pill. Had to buy a pill cutter. Otherwise, it did make me a little moody and anxious but I did not have any other major symptoms. Took for 7 days for staph infection on skin."

7 / 10
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  • Tired
  • August 16, 2019

Bactrim (sulfamethoxazole / trimethoprim) "Took bactrim 4 days for skin infection then quit due to not sleeping or being able to eat, I drank plenty of water but ended up feeling like my head was going to explode, joints aching, vision blurry, felt like I was being poisoned. The doctor said to continue taking just make sure you eat I let them know I was not able to eat, so I quit on my own nobody's going to know what is going on with their body better than themselves and it was just poisoning me. Three days after stopping Bactrim I have rash all over body and a week later still feel like my head is going to explode, very tired and vision blurry. Doctors put on my file to never take again as I am allergic to it"

1 / 10
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  • Dane
  • September 15, 2019

Bactrim (sulfamethoxazole / trimethoprim) "I had an ingrown toe nail so my pod. removed it & put me on cephalexin for a week. After taking all of them my toe was still infected. She put me on Bactrim to be taken twice a day for 10 days. 24 hours after my first dose my mood completely changed I was depressed & miserable. Day2 I was spinning it was impossible to function for daily tasks, & I had no appetite. Day 3 had a full blown panic attack then extreme anxiety & following that several heart palpitations. Day6 I had a rash across my midsection. I stopped taking them that day and called my pod. as my toe still wasn't getting better. She advised I stop & see her later on that day. She wound up removing another piece of nail that had been left behind. When I told her all of the symptoms she said that I'm allergic. As a person who suffers from food allergies this terrified me. After a week the nausea, headache & spinning started to lighten up but it took around two months to get back to my normal routine. And to think...these symptoms are NORMAL for this medication."

1 / 10
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  • Lisa
  • Taken for less than 1 month
  • August 12, 2018

Bactrim (sulfamethoxazole / trimethoprim) "I was prescribed Bactrim after having an abscess on my leg drained. I started feeling horrible immediately. Joint pain, nausea, loss of appetite, high fevers. I ended up in the hospital for 3 days for drug fever, and am still feeling the effects a week after coming home. I would not suggest taking this."

1 / 10
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  • Jules
  • Taken for less than 1 month
  • April 8, 2019

Sulfatrim (sulfamethoxazole / trimethoprim) "Prescribed Sulfatrim for skin infection. Took 1 pill and began to feel body aches and pains and felt chilled with fever and flu like. Woke up in the morning drenched in sweat with severe pain in my side radiating to my tail bone. Couldn't sit, couldn't stand and couldn't lie down. Agonizing pain in my joints. Took another pill as I did not realize it was the drug doing it. Felt like I might die. Went to doctors in agony. Told to stop taking and given another antibiotic. Was to sick too take the other antibiotic and too afraid. After a few days, the pain subsided but missed a week of work because of it. Cannot imagine what other damage it did. Will never, ever take again. I thought I would die on this drug."

1 / 10
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  • Ruthie
  • Taken for less than 1 month
  • November 29, 2019

Bactrim DS (sulfamethoxazole / trimethoprim) "Gahh. I’m on day 4 for a staph infection. Went from waking up ready to face the day head on, feeling 90% better than I was earlier in the week. But I took my pill and here I am, back in bed. I can’t help but wonder if the awful side effects is the die off reaction of the bacteria"

7 / 10
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  • dude...
  • Taken for less than 1 month
  • October 11, 2016

Bactrim DS (sulfamethoxazole / trimethoprim) "Bactrim ds cleared up my infected finger, just like most antibiotics do. The difference is in the side effects. The nausea and diarrhea are worse on this one. But the biggest problem was that my depression which I had under control with medication became worse than ever overnight. I don't know whether it interfered with my antidepressant (bupropion xl) or just aggravated the symptoms so much that it was uncontrollable. Either way, I spent a week alternating between despair and rage on a hair trigger. I would not try this again."

3 / 10
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  • Lilly...
  • Taken for less than 1 month
  • January 26, 2021

Bactrim (sulfamethoxazole / trimethoprim) "I had a facial abscess lanced at urgent care and prescribed Bactrim in case it was MRSA. I took it for about 8 days twice daily and lost my appetite, got headaches and felt anxious and depressed. I continued to get cystic acne behind my ears, mostly the ear by the abscess that was drained so the dermatologist PA told me to take Bactrim for another month, once a day. I took it another 12 days until I began having knee joint pain and achyness in my legs like I've got the flu. Oh I was also getting the chills. I've been off it 3 days and still having very bad leg pain that's caused me to have a panic attack and extreme mood swings and depression. I know it's from this antibiotic... I'm praying that the pain goes away as is debilitating and I was a healthy 30 year old prior to this."

1 / 10
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  • Mel
  • Taken for less than 1 month
  • April 25, 2017

"I was recently exposed to MRSA. (hazards of my job) Few days later, I woke up to my right eye swollen shut and oozing yellow pus. Whites of eye was red. I immediately went to Urgent Care. They squeezed out a sample from my eyeball to send to the lab. In the meantime, they expressed concern that it was either MRSA or a really bad case of pink eye. I am being treated for both right now. The medication proved to be a miracle - its killing the infection in my eye. Swelling went down, minimal pus coming out as of this morning, red is now pink - just over 24 hrs after starting the medication. I have had no side affects from the medication."

10 / 10
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  • Anonymous
  • September 28, 2011

Bactrim (sulfamethoxazole / trimethoprim) "Prescribed Bactrim for boils on abdomen/legs. I was only able to take it for 3 days, due to the adverse reaction. The boils are much better (and I hope they don't come back), but the back pain, abdominal pain, nausea and diarrhea were enough to make me stop taking it. Plus, I'm not sure if this is a medicine of choice for anyone with ulcerative colitis, but now I'm having a huge flare of that! "

5 / 10
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  • Wd40oz
  • May 17, 2015

"I was prescribed a 10 day course for cellulitis and after 5 days the infection cleared but I'm so nauseous, gassy and dizzy I had to stop. I feel so bad I'm borderline suicidal. It's an effective drug for sure but brutal on the GI tract. I pray this feeling goes away soon..."

5 / 10
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  • Danny...
  • Taken for less than 1 month
  • May 24, 2015

"I had to take this for a boil and it healed the boil and made it go down and kinda get a scab over it but the side effects are crazy you have diarrhea your head hurts all the time and I'm so tired all the time. I was prescribed the medicine for 7 days to take twice a day. Overall the medicine did its job but had side effects"

8 / 10
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17 Report

Reviews may be edited to correct grammar/spelling or to remove inappropriate language and content. Reviews that appear to be created by parties with a vested interest are not published. This information is not intended to endorse any particular medication. While these reviews may be helpful, they are not a substitute for the expertise, knowledge, and judgement of healthcare professionals.

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