Sulfamethoxazole / trimethoprim for Bacterial Infection User Reviews (Page 3)
Brand names: Bactrim, Bactrim DS, Septra, SMZ-TMP DS, Co-trimoxazole, Septra DS, Sulfatrim Pediatric, Bactrim IV, Bactrim Pediatric Bethaprim Bethaprim Pediatric …show all brand names
Reviews for Sulfamethoxazole / trimethoprim
- Kyl...
- Taken for less than 1 month
- September 30, 2018
"My experience with this drug is horror. The first night I took the drug, everything was fine. I've been on an anxiety medication prior to taking Bactrim. However, the anxiety that I felt day 2 was like anxiety I've never felt before! I've thrown up in the past, but with Bactrim, I couldn't eat anything! I threw up almost every meal that I ate and woke up all throughout the night! The nausea and insomnia were so bad, these resulted in even more heightened anxiety levels. I stopped taking it after 3 days because I could not handle it! It did help my infection, but in my opinion, it wasn't worth it."
- Lil...
- Taken for less than 1 month
- May 20, 2019
Sulfamethoxazole / trimethoprim "I have dysuria, furuncle of the groin, cellulitis at the same time. I was given sulfamethoxazole plus TMP/DS 800 every 12 hours. I also have Hashimoto's disease and took my levothyroxine a while after taking Bactrim (sulfamethoxazole plus TMP). The first day I started having cramps on the left side of my stomach, thinking it was normal. I took the second pill after 12 hours, and I was worse than before: light headache, nausea, full and heavy stomach feeling. Then I took the third pill in the morning, and soon I was having chest pain, nausea, tired irregular heartbeat, fatigue, tight chest, pain in my teeth, lips, and muscle pain. The symptoms are not improving. I called the pharmacy, and they wanted me to call my doctor, but I will stop this medication, as per my primary doctor. I will have a long talk with them tomorrow, as according to my medical records, I shouldn’t have been on this medication."
Frequently asked questions
- What happens if antibiotics don’t work for UTI?
- What drugs should be avoided with a sulfa allergy?
- Does Bactrim cause headaches?
- Can I drink alcohol when taking sulfamethoxazole / trimethoprim DS?
- ann...
- Taken for less than 1 month
- November 22, 2020
"I got diagnosed with a UTI and was prescribed this medication. I usually don't experience any side effects or mild side effects with antibiotics. The first 3 days were pretty normal. Fast forward to the fourth day, I was feeling feverish. Had really bad headaches and nausea. I'm on my 6th day, and I haven't been able to get good sleep for 2 days for some reason. Also have no appetite, and my stomach feels terrible. This is probably the worst I've felt with any antibiotics. Not even sure if it cleared up the UTI."
- Anonymous
- April 28, 2011
Sulfamethoxazole / trimethoprim "Pain and swelling in the vicinity of my tailbone led to an emergency room visit where I had a pilonidal cyst drained. After the doctor incised and drained my cyst, he prescribed me Bactrim and Keflex. He explained that the Keflex was intended to treat the infection if it was MRSA while Bactrim would cover all other bases. A week into my 10-day course of antibiotics, I went to bed with a developing fever. In the morning, I awoke to discover that my entire body was covered in a red, splotchy rash. I immediately went to a medical professional who informed me that I was likely having a severe allergic reaction to Bactrim. I was informed that my fever and rash would persist for days to weeks and may progress to anaphylaxis."
- Joh...
- Taken for less than 1 month
- July 22, 2019
"After two days of taking the sulfamethoxazole/trimethoprim medication, I started having panic attacks, anxiety, intense cold, among others. It's been three years since I took it. Since then, I've been on antidepressants."
- She...
- Taken for less than 1 month
- June 14, 2017
Sulfamethoxazole / trimethoprim "My 83-yr-old father took only five (5) pills over the course of a few days and ended up in the hospital in acute renal failure and a 103-degree fever. This man was not on any medications prior to taking Bactrim DS and was still working. His kidney functions have not returned to normal, his blood platelets are critically low, his blood pressure is now elevated, as well as his blood glucose. His whole life has changed for the worse all because of five (5) Bactrim pills. I just hope he's on the road to recovery."
More FAQ
- Des...
- Taken for less than 1 month
- January 29, 2021
Sulfamethoxazole / trimethoprim "I had taken the Bactrim 800/160 twice in a day as told. When I got it after my appointment and before bed. That night I was up until 6 am throwing up the medicine. I felt nauseous, confused, and my stomach hurt bad. I had food in my stomach, so I’m unsure why it acted this way, but I would never take it again."
- pmb...
- Taken for less than 1 month
- June 7, 2019
Sulfamethoxazole / trimethoprim "I've been fighting a frustrating cavitational infection in my palate for years. I've lost count of how many different kinds of antibiotics I've taken that were useless. They ruined my gut, made me miserable, and gave me headaches. I'm loving this stuff, Bactrim!! Not one side effect!"
- Roc...
- Taken for less than 1 month
- July 23, 2020
"I had an abscess that popped, and I believe I got a staph infection. Day 1 on sulfamethoxazole with trimethoprim combo, I could tell the infection started healing overnight, felt a tad nauseous. Day 2, started feeling a little dizzy and more nausea. Now on day three, I puked all over the golf course trying to hit a couple of balls. Feel like complete crap. Head feels stuffy. Have no energy. Oh, and last night I had the craziest dreams I’ve ever had. I’m on track to losing my penis by day 10. Scared."
- Anonymous
- Taken for less than 1 month
- October 20, 2020
"Day 2 of no sleeping on this medication. I am narcoleptic, so that is quite a feat. Unable to breathe and extended panic attacks. Shaky hands. Strange/unusual thoughts and worsening depression. Middle back pain. This medication is the worst of the worst."
- Jac...
- July 13, 2019
Sulfamethoxazole / trimethoprim "After 2 days, my fever rose to 102.8. I had severe kidney pain and a burning sensation under my skin. Diarrhea soon followed, and then I began throwing up. I went to a different doctor, and she did a blood test and urine test. My red blood count was very high, but my white count was perfect. She told me to stop Bactrim immediately and to never take it again. I felt like I had been poisoned."
- jam...
- Taken for less than 1 month
- January 3, 2020
Sulfamethoxazole / trimethoprim "Was on the Bactrim antibiotic for 1 week to clear up epididymitis. It took around 4-5 days to notice any difference, and I didn't really experience any sort of side effects other than anxiety, which is something I already struggle with anyway, but it seemed to amplify it, and at times I felt confused and kind of dizzy. Make sure to drink lots of water, and also, I would recommend taking it with food to avoid any stomach problems. Overall, the pain from epididymitis is gone, and that is all I care about, I think the side effects are worth it, and remember they are only temporary."
- Uns...
- June 22, 2015
Sulfamethoxazole / trimethoprim "Was prescribed this almost 2 years ago for a skin infection but quit taking it after 3 days because of severe anxiety, indigestion, nausea, fatigue, dizziness, and who knows what else. At the time, I was dealing with panic attacks, so when my current doctor prescribed it last week, I decided, since I was feeling better, to give it one last effort. Days 1-2 were good. Skin was clearing, and other than being tired, I had no side effects. By day 3, I got a headache that was relentless, I was shaky, couldn't sleep at night but couldn't stay awake during the day, diarrhea started, and I quit the medicine at my doctor's advice. It's been over 48 hours since my last dose, and I still feel like crap. My neck hurts, and I'm still feeling incredibly anxious."
- Nei...
- August 12, 2014
Sulfamethoxazole / trimethoprim "Have been taking this medicine for 5 days for cellulitis that developed on my leg below the knee. I had waited 7 days prior to seeking treatment. The first three days after getting an injection, type not known, thick solution, and needle, and taking Bactrim and Cephalexin showed little signs of improvement. The 4th day showed signs of reduced swelling, the 5th day swelling all but gone, reduced redness and warmth at the site. The 6th day redness reduced greatly and leg feels normal. However, side effects: extreme fatigue, nausea, dry mouth, overall ill feeling. Overall benefits outweigh side effects."
- Mor...
- Taken for less than 1 month
- April 17, 2019
"Bactrim was the WORST medicine in the world! I was prescribed Bactrim for 10 days and only took it for 6. Every day something new was wrong. Days 4 & 5 were the worst. I was extremely sensitive to light and had vivid suicidal thoughts and became extremely depressed. All I wanted to do was sit at home and cry. Day 6 I decided to stop Bactrim because my severe headaches began to worsen and I became extremely dehydrated. The medication urges you to drink “plenty” of water, but I drank 6 bottles of water in 3 hrs and was reaching for #7-that’s MORE than “plenty” if you ask me. I don’t recommend!!☠️"
- Dee...
- Taken for less than 1 month
- December 4, 2019
"I've never had such a severe negative reaction to a medication as I did for sulfamethoxazole with trimethoprim. I became nauseous after the second dose. After 3 days, on Saturday, I called the prescribing practice Dr. on call. I reported severe nausea, with stomach pain, weakness, fatigue, and headache. He stated I had not yet received a therapeutic dose and to continue taking the medication. After 6 doses, I returned to the prescribing Dr., barely able to function. The Dr. advised to discontinue use and noted on my chart that I had a bad reaction. It's been about 36 hours since my last dose, and I'm still very sick: stomach pains, nausea, headache, fatigue. I'm so debilitated I can do nothing but lay on the couch. This is a horrible drug for me and others. Use extreme caution."
- Dav...
- April 23, 2013
Sulfamethoxazole / trimethoprim "Some upset stomach using Bactrim, other than that not a problem. One month using this has finally cleared up sinus, inner ear, and nasal infections lingering for months. Highly recommend this medicine, also using with Rifampin."
- Hap...
- Taken for less than 1 month
- April 1, 2023
Sulfamethoxazole / trimethoprim "The reviews of this medication had me absolutely terrified, but a few of the positive reviews gave me the courage to try it. So I felt obligated to share my review to help calm the fear of others. I took this medication twice a day for seven days. I took it with food, and I also took one Florastor probiotic capsule with every Bactrim pill. I felt fine for the entire seven days. No side effects whatsoever. That being said, there is a long list of the types of people who should NOT take Bactrim. I recommend anyone taking this medication look up the warnings and contraindications and speak with a pharmacist if they have any questions. Best wishes, everyone!"
- Whi...
- Taken for less than 1 month
- February 19, 2017
Sulfamethoxazole / trimethoprim "I had a bacterial infection and feeling ill, and the doctor prescribed Bactrim. I didn't think it was helping as my illness took a turn for the worst. I had fever, chills, muscle weakness and pain, stomach pain, and I couldn't get out of bed. I'd start to feel better after a few hours and thought it was finally working. Nope. I took my next dose of Bactrim and all the symptoms came back full strength, and I was severely ill again. I finally linked it to Bactrim and stopped taking it. My symptoms cleared up over the course of a few days. I learned my grandmother and mother have a severe sulfa allergy, and I found out the hard way I do too. Words just don't describe how sick I was on this medication."
- S S...
- April 12, 2017
Sulfamethoxazole / trimethoprim "I have been taking Bactrim for a total of 3 days. I have awful headaches, the shakes, spiky fevers, tightness in my chest, and can barely keep my eyes open from exhaustion. I have 7 days left of treatment, and I'm not sure I'm going to finish it. I feel worse with the medication than I did with the infection. Granted, it has reduced swelling and pain at the infection site. So I guess it's doing one thing right."
- Mam...
- Taken for less than 1 month
- May 2, 2018
Sulfamethoxazole / trimethoprim "I was prescribed a 10-day course of Bactrim as a preventative measure after an injury. My wound healed well and no major problems other than nausea until Day 9, when I broke out in a rash. Started on my arms, quickly spread to my trunk, legs, and face. The rash was painful, swollen, and hot to the touch. It felt similar to a bad sunburn. Started taking Benadryl every 4-6 hours until I could get to the doctor, where I got a steroid shot. So far, that seems to be helping a lot. The doctor says I am allergic to sulfa drugs and make sure never to take it again or it could be even worse next time."
- Joa...
- Taken for less than 1 month
- November 18, 2019
Sulfamethoxazole / trimethoprim "For 6 months, I had a sore throat. It felt like a lump in my throat. I went to 5 different doctors because, well, I'm in North Dakota. Sore throat for 6 months. Blood test normal. Negative for mono. Laparoscopy negative for other diseases. Red swollen tonsils. I was finally given Bactrim DS by a doctor who flew in from another state to see me and other patients. An ENT specialist, she prescribed this wonderful medication. I had strep and pus stuck in my throat from 2 head colds back-to-back months earlier. My side effects from Bactrim DS: yellow diarrhea for the duration of the medicine. Not bad, though. Extreme drowsiness an hour after taking it, which was unexpected for just an antibiotic. Did not drink alcohol with it either. Took one pill twice a day. Shaky from blood sugar drop on the first day, but I ate full meals and was okay. Felt better after 4 days. No sore throat since. Took the whole bottle to kill all the germs. Love this medicine!"
- 777...
- Taken for less than 1 month
- October 26, 2018
"I was prescribed sulfamethoxazole/trimethoprim for a bacterial infection. The first pill I took about 7 p.m., and I couldn't sleep all night, I was wide awake and felt as though a train was running through my muscles. The pain was so severe that I felt as though I was going to die. I couldn't tell if it was helping my infection or not since the pain was so severe. I have not taken another dose, as nothing is worth that much pain. I will never take that antibiotic again."
- Mea...
- Taken for less than 1 month
- October 12, 2019
Sulfamethoxazole / trimethoprim "I am currently taking this medicine to help me fight a serious bacterial infection. Every time I take it during the day, nasty side effects occur... the feeling of throwing up, very bad stomachaches, feeling like I have diarrhea. However, I have been defecating fine but still feel like I have diarrhea due to the extremely bad stomachache I am currently having. My throat is getting better, and I sound less congested. I think that's one of the many benefits that it has. I am hoping to be on a different drug that will help me get better faster and never have this very strong drug negatively affect my stomach anymore!"
See also:
Learn more about Bacterial Infection
- Antibiotic Resistance: The Top 10 List
- Antibiotics & Alcohol: Do They Mix?
- Antibiotics 101: Common Names, Types & Their Uses
- Can You Drink Alcohol with Antibiotics?
- Common Side Effects from Antibiotics, and Allergies and Reactions
- Middle Ear Infection FAQs (Acute Otitis Media)
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- Sulfamethoxazole and Trimethoprim Injection
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Bactrim, Septra, SMZ-TMP DS, Septra DS, ... +3 more
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- Sulfamethoxazole Trimethoprim Oral Suspension prescribing information
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- Sulfamethoxazole and Trimethoprim Suspension (FDA)
Other brands
Bactrim, Septra, Co-trimoxazole, Sulfatrim
Sulfamethoxazole / trimethoprim "This medicine is working for me, but it makes me feel horrible. I've been shaking, have had a rapid heart rate, nausea, extremely thirsty, chills (no fever), dizziness, and cold hands and feet. I did find that taking probiotics helps. It doesn't take away everything, but it helps with the nausea. The only reason I continue to take it is because the doctor said this could be MRSA."