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Solriamfetol and Tiredness: What Users Say

Brand names: Sunosi

Tiredness: mentioned by 6 users (7.3%)

Based on user experiences from 82 Solriamfetol reviews, the following table shows the most commonly mentioned side effects.

All user comments are moderated by Drugs.com. Each review is verified for relevance and screened for inappropriate content. Side effects are user-reported and not clinically verified.

increased heart rate 8.5%
irritability 8.5%
high blood pressure 7.3%
tiredness 7.3%
headaches 6.1%
insomnia 6.1%
anxiety 4.9%
fatigue 4.9%
nausea 4.9%
depression 3.7%

Reviews for Solriamfetol

Commonly mentioned side effects
  • Dis...
  • Taken for 6 months to 1 year
  • March 3, 2020

For Narcolepsy "I have had narcolepsy and been on Adderall or Nuvigil for 20 years. I did the 75mg to 150mg and at 12 weeks, I thought my life has changed. Then at 16 weeks, I come home from work more exhausted and tired than I can remember, as if I’m not taking anything. I’m withdrawing from life - to sleep by 7pm. Unless I throw Ritalin at it, which I’ve never had until now (odd?). I’m worthless by 5. Then I’m up at 3:30 or 4am. Let me off the roller coaster ride."

3 / 10
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  • Dis...
  • Taken for 6 months to 1 year
  • March 3, 2020

For Narcolepsy "I have had narcolepsy and been on Adderall or Nuvigil for 20 years. I did the 75mg to 150mg and at 12 weeks, I thought my life has changed. Then at 16 weeks, I come home from work more exhausted and tired than I can remember, as if I’m not taking anything. I’m withdrawing from life - to sleep by 7pm. Unless I throw Ritalin at it, which I’ve never had until now (odd?). I’m worthless by 5. Then I’m up at 3:30 or 4am. Let me off the roller coaster ride."

3 / 10
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  • jwa...
  • November 3, 2019

For Narcolepsy "I got the free trial of 15 Sunosi pills. When I started using it, I didn't feel any better, still felt very tired. On the 2nd day of use, I started getting a bad headache and still felt really tired. I also checked my blood pressure, it was starting to get higher than normal, and my stomach was starting to bother me. After the 3rd day, my stomach got worse, still had a bad headache, and blood pressure was getting higher, some slight chest pain. So after that, I stopped taking it, and now it's been a week since I have been off of it, and no headache or stomach problems, and blood pressure is down. The only thing I know is all the drugs that I have taken for narcolepsy had bad side effects, and they all seem to be a bandage to fix the problem. I hate all of these meds because no one knows what damage you're doing to your body taking these meds, that's why none of this stuff is good for you."

1 / 10
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107 Report

Frequently asked questions

  • Tir...
  • November 13, 2020

For Obstructive Sleep Apnea/Hypopnea Syndrome "I've been taking Sunosi 75 mg for over a week now. The first couple of days, I didn't notice any difference. Normally, I am in bed by 7:30 or 8 pm at the very latest because I could not stay awake. I yawn all day long and am just ready to drop. I can never get enough sleep, even if it's 12 or more hours. On the third day of taking Sunosi, I had to catch myself because I looked at the clock, and it was 10:30 pm. I was not ready for bed, but I forced myself because I knew I would pay for it in the morning. I woke up before my alarm went off at 4 am. It has been the same every day since. I still yawn occasionally during the day, but I am able to stay up much later and wake up easier in the morning. Thank you, Sunosi!"

9 / 10
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  • Coc...
  • Taken for 1 to 6 months
  • December 31, 2019

For Narcolepsy "I was given 75 mg Sunosi for my narcolepsy. On the positive side, I can tell the difference in energy, concentration, motivation, and productivity, and there is a decreased need for a midday nap. Negative: this drug causes major heart issues. I have atrial fibrillation, and I cannot take this medicine regularly as it increases my heart rate to 120 and raises my blood pressure. However, I try to take it once in a while if I have a commitment or something important to do, like running errands or needing to go somewhere. I am on Xyrem 4.5 for narcolepsy with excessive daytime sleepiness, which, although it helps me sleep about 6-7 hours, no longer helps me wake up refreshed as it did the first time I tried it. I also take Doxepin to sleep longer, but it leaves me feeling too tired the next day and counteracts the effect of a good night's sleep. I take a nap in the afternoon, except on the day when I take Sunosi."

8 / 10
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  • Ms ...
  • Taken for less than 1 month
  • September 20, 2019

For Obstructive Sleep Apnea/Hypopnea Syndrome "Sunosi doesn’t work for me. It’s been about a week at 150 mg. It makes me crash hard at the end of the day (around 4 p.m.). At the end of the day, I’m more tired than if I didn’t take it at all. I’ve been waiting for this “miracle medication” for a few months, and I’m disappointed. Nuvigil was great, but it stopped working."

1 / 10
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27 Report

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