Solriamfetol and Nausea: What Users Say

• Sle...
• Taken for 1 to 6 months
• July 30, 2020

For Obstructive Sleep Apnea/Hypopnea Syndrome "I've been taking Sunosi for around two months for OSA. I started at 75 mg daily, and I've been taking 150 mg for about two weeks. It is probably important to note that I also take 250 mg of Nuvigil and 20-60 mg of Adderall daily as well. I started the Sunosi with the goal of stopping the Adderall. My diagnosis is severe OSA with excessive daytime sleepiness. Narcolepsy was ruled out, although I experience restless legs and occasional sleep paralysis. I hold my breath in my sleep and wake up feeling like I am suffocating because I cannot force myself to breathe. I have used a CPAP regularly for more than 10 years, and the data shows that my sleep apnea is well controlled. But even so, I sleep between 15 to 18 hours per day. Sunosi was ineffective at 75 mg. At 150 mg, I am awake but too fatigued to do anything. It has caused anxiety, headaches, excessive sweating, nausea, and diarrhea."

• Con...
• Taken for less than 1 month
• March 8, 2023

"So, about 3 weeks ago, my neurologist gave me a trial for Sunosi since Ritalin wasn't doing anything to improve my EDS. I have idiopathic hypersomnia, and it is honestly a struggle even with the medication I currently have, modafinil. I've been on modafinil for about 2 years now, 200 mg twice daily. It helps, but it doesn't do enough. When the doctor gave me Sunosi, I thought maybe this one would be the one that helps. I was wrong. I barely notice a difference in my wakefulness, and on top of that, the side effects are awful. I feel like I can't catch a full breath, I'm getting dizzy all the time, my eyes feel like they can't focus properly, and the tremors are fairly severe. I can't hold anything steady, and my legs are extremely shaky as if I've just done a marathon. The headache is awful, and it makes me feel like I'm slightly detached from my own body. My chest feels tight, and I'm always nauseous. I have felt off for about a week now, with the symptoms worsening. Not the drug for me."

• Rob...
• Taken for less than 1 month
• July 10, 2022

For Obstructive Sleep Apnea/Hypopnea Syndrome "Excessive daytime fatigue. I tried armodafinil 150 mg first, and it worked well by the second week, then energy uptake stopped, and I suffered through pounding heart, restlessness, anxiety, and nausea. Next was Sunosi 75 mg. It skipped the ‘energy’ part and went straight to all the awful side effects. I held on to it for about 10 days before it was intolerable. Now taking Adderall, 10-15 mg, once a day. I experience a window of energy for about 2 hours (nothing excessive, just alert like after a good night's sleep, which I haven’t had for 2 years). Sometimes with the med, I experience a ‘crash’ of agitation and exasperated cervical dystonia, but that was pre-existing and is usually non-existent because of treatment therapy. The side effects of the non-amphetamine drugs were too much to tolerate, with little relief. I will stick to the occasional Adderall, which I take every 2-3 days, when my responsibilities become backlogged due to my inertia."

• Joa...
• Taken for 6 months to 1 year
• October 11, 2020

For Narcolepsy "I get nauseous and feel like my sinuses are full an hour after taking Sunosi. It only lasts me 4 hours, and I crash. I have been taking it for six months, and it has not improved my quality of life."