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Sofosbuvir / velpatasvir User Reviews & Ratings (Page 2)

Brand names: Epclusa

Sofosbuvir / velpatasvir has an average rating of 7.8 out of 10 from a total of 402 reviews on Drugs.com. 66% of reviewers reported a positive experience, while 12% reported a negative experience.

Reviews for Sofosbuvir / velpatasvir

  • Anonymous
  • Taken for 1 to 6 months
  • April 14, 2019

Epclusa (sofosbuvir / velpatasvir) for Hepatitis C "65yr old Geno 3. It is 6mths since finished Epclusa and I have loss of hearing in my right ear, nausea, numb fingers and can't sleep. I got rid of virus but I really did feel better BEFORE I did treatment. Liver clinic and Dr no help whatsoever, no one seems to know anything except that these horrible feelings won't be going away and I feel like a guinea pig. I can't get any help ,no one cares, Gilead makes money. I had this treatment here in Australia"

1 / 10
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  • Havoc
  • Taken for less than 1 month
  • July 19, 2019

Epclusa (sofosbuvir / velpatasvir) for Hepatitis C "This is my 2nd week on Epclusa. I caught the disease early with no liver scarring. I was terrified to begin treatment regardless of the positive reviews. The 1st week was rough but nothing compared to the free life I am headed towards. Day 1, nothing. Days 2 + 3 I had such unbearable fatigue and weakness I could hardly walk and required help from my family to get through the day. I was concerned that would be my life for the rest of the treatment and was afraid. Day 4 I spontaneously recovered but I was still weak, not alert. Day 4+ I RAPIDLY improved. Yesterday I felt better than even before I had started the medication, 0 side effects OR symptoms. I have night sweats but those are disappearing. I haven’t had nausea or headache, have had slight diarrhea. Those two days of despair were a small price to pay for the freedom I will get. Don’t fret about starting this medication. The first pill is your ticket to your new beginning."

8 / 10
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  • Emmyy
  • July 29, 2022

Epclusa (sofosbuvir / velpatasvir) for Hepatitis C "Hey I started taking this drug Epclusa in June 2022 diagnosed & started this drug. 2 weeks in blood test show negative, great, but noticed straight away I had a weird heart beat on taking it, a high blood pressure feeling. Also feeling sick gradually went off food lost my appetite, so lost weight. By the way I’m half way thru and I still have no appetite I’m still loosing weight. I get severe headaches and sickness so feel like I’m loosing my mind. Also aches, pains, joint pain, head pain ,back pain, sore throat. I feel like absolute rubbish. I can not understand the weight loss I’ve been reading thru these and not once seen weight loss am I the only one ? Anyway point is I feel like I’m dying"

5 / 10
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Frequently asked questions

  • Hep...
  • Taken for 1 to 6 months
  • October 2, 2021

Epclusa (sofosbuvir / velpatasvir) for Hepatitis C "Finished taking Epclusa 1/3/2019. Almost two years later I continue to have severe side effects. I had always been an extremely high energy person working and on the go for 16 plus hours a day. Since taking Epclusa I continue to experience severe fatigue, memory loss (brain fog) and tinnitus. I have not been able to return to work since Epclusa. At this point it appears that I traded a shorter but quality life with hepc for quantity of life that's only watching it pass by. I'm continuing to search for answers for something to help restore my health. If I had known what the results would be I would probably not have taken the Epclusa."

1 / 10
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  • Mandy
  • Taken for 1 to 6 months
  • February 9, 2020

Epclusa (sofosbuvir / velpatasvir) for Hepatitis C "I’m almost 12 weeks on Epclusa and to say it’s been hard would be an understatement. I’ve been beyond tired- I’ve tried taking the medication both in the morning and at night. I’ve found that at night works best for me. I’ve become extremely irritable and depressed. I’ve also recently had this weird hormonal issue where my boobs hurt and I have acne (not even close to having my period nor pregnant). I never got any headaches or ear ringing so that’s a plus. I know it’s all going to be worth it in the end and I would not have done things any differently. For those of you reading through hundreds of reviews like myself- know that it will get better. I also have to take it for 3 months due to having type 3. Cheers to being hep c free. I received the medication for free through Support Path also Gilead. Look into it if you don’t have insurance!"

6 / 10
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Are you taking this medicine?

  • Valerie
  • Taken for 1 to 6 months
  • December 29, 2021

Epclusa (sofosbuvir / velpatasvir) for Hepatitis C "I am 62 years old and haven't used I.V. drugs since I was 22. Recently found out I have been infected with Hep C for 40 years. I had no symptoms but after 3 tests I chose Epclusa. Did not have any side effects at all. No headaches no nausea no bowel changes no fatigue. I had strain 1a and 1b with a viral load of 18 million. The doctor called me on the phone and said I am cured that no virus is detected in my blood. Unfortunately, my stomach is noticeably bloated and hard up high. I can't eat much at all or it will bloat to the point of pain. I am also making clay colored bowel motions occasionally which is both a symptom of liver disease and hep c. I felt fine before I took this medicine now I feel like I've done damage to my liver. I really don't believe I'm cured.I feel like there was no point in taking this medicine. I felt better and looked better before I took it."

5 / 10
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  • jjjj
  • Taken for 1 to 6 months
  • March 19, 2019

Epclusa (sofosbuvir / velpatasvir) for Hepatitis C "Completed the 3 months of Epclusa treatment in December 2018 for my Hep C, it is now March 2019 and the side effects are worse now. I have constant buzzing in my head/ears (tinnitus), numbness & tingling, internal shakiness, insomnia, brain fog, very weak, depression, and back pain. I regret taking Epclusa. I felt better before the treatment. I have gone to a Naturopathic Practitioner, Chiropractor, and Acupuncturist to try to help but it is not any better. I don't know what to do at this point and it is scary."

1 / 10
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More FAQ

  • Jonny
  • Taken for 1 to 6 months
  • August 1, 2019

Epclusa (sofosbuvir / velpatasvir) for Hepatitis C "I took my last pill today after completing 3 months. I had HCV genotype 3, for about 27 years. During treatment I felt tired in the afternoon and after doing any exercise. I'd take a nap for a few hours then I'd feel pretty good. No tinnitus but sometimes when relaxing I'd feel numbness in my hands or fingers. It didn't last long. Overall I am very happy with Epclusa. Prior to treatment I'd read all these horrible stories about side effects. Thankfully whatever side effects I had were not too bad. My blood work at 4 weeks came back as virus undetected, so after 2 more months on the med I am hoping that all the little hiders have been destroyed."

10 / 10
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  • Moni
  • Taken for 1 to 6 months
  • April 11, 2021

Epclusa (sofosbuvir / velpatasvir) for Hepatitis C "Just started my third month of Epclusa. So far not much of side effects. A little anxiety or irritation at times. No nausea, diarrhea, or anything like that so far. My doctor won’t test until a few weeks after final dose is taken. I did notice after the first four weeks I have much more energy and not feeling so depressed anymore. I will update again once I’ve finished taking the medication and after I’ve been tested again for viral detection."

9 / 10
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  • Wacka...
  • April 22, 2017

Epclusa (sofosbuvir / velpatasvir) for Hepatitis C "I finished epclusa two weeks ago. I've had gum pain, and pain in my legs since. I'm glad to be completed. I'm not sure why everyone keeps leaving reviews only a few weeks into treatment. My sides effects varied weekly...so I couldn't really give a review while taking the drug. I also have a ringing sound in my head all day everyday, and no hearing loss. I hope that goes away with time. Undetected since week 4. I'd like to hear from others who are months into recovery after this. Do you feel better? Did your sides go away?"

5 / 10
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  • rudone
  • Taken for 1 to 6 months
  • February 11, 2019

Epclusa (sofosbuvir / velpatasvir) for Hepatitis C "I am 71 - have had Hep C for who knows how long. Did the interferon / procrit six years ago - don't do it - doesn't work and the side affects are psychologically and physically destructive - can lead to suicidal depression - had two friends die on it. 90 days since treatment with epclusa - no virus detected."

10 / 10
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  • Lizzy...
  • Taken for 1 to 6 months
  • August 21, 2019

Epclusa (sofosbuvir / velpatasvir) for Hepatitis C "I'm 2 weeks off of finishing the Epclusa drug I'm so exhausted all the time, I hurt all over even doing nothing leaves me in physical pain and physically exhausted. I was not sick before I started but have been sick since the first tablet. I have headaches, weird dreams, pain on my feet pain in my legs pain in my back sleeping only helps for a couple of hours can barely leave the house. If this dosn't work I'm never going to take anything else"

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  • Smitty
  • July 26, 2019

Epclusa (sofosbuvir / velpatasvir) for Hepatitis C "Took Epclusa for 90 day course of treatment, fatigue, brain fog, lethargy, moody, lots of anxiety. 30 day blood work showed no Hep C. 2 weeks till I get final blood work done. Hopefully I’m cured. Still tired and lethargic but not as bad. I’m 64 years old and am glad I did it. Don’t let the side effects hold you back or scare you. Just suck it up and do it. Price is frikkin outrageous but I got help from a grant from PAN organization. There’s financial help out there. If you wanna be cured, do it!"

10 / 10
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  • Kat
  • Taken for 1 to 6 months
  • September 14, 2018

Epclusa (sofosbuvir / velpatasvir) for Hepatitis C "Today, 31 days after starting this WONDERFUL drug, my lab test came back "Not Detectable" I have had Hep C for 53 years, without knowing it for 52 years. Blood transfusion in 1965. I have had no side effects. My advice to everyone that is starting it: Drink at least 100 ounces of water every day, limit caffeine, fake sugars and spicy stuff. Coffee, hot sauce and Splenda were aggravating my tinnitus, and cutting back fixed it. Best of luck to everybody, and thank you Gilead for developing this drug! You saved my life!"

10 / 10
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  • Madei...
  • Taken for less than 1 month
  • April 21, 2017

Epclusa (sofosbuvir / velpatasvir) for Hepatitis C "So, I began taking this medication for Hep C contracted from IV drug use. 24 years old. Doctor explained that since I had PPO insurance they would most likely cover the cost of the medication which I believe goes for around 75k for a 3 month supply. The medication was delivered straight to my house. Genotype 2b. Viral load was 1.7mil initially. I started taking the Medication March 30th, 2017. I had labs done this week to check on progress. After just 21 days of taking Epclusa viral load is completely undetectable. Initial fatigue first week, no symptoms after that. Great medication! Grateful that this option was available to me. Was absolutely worth it!!"

10 / 10
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  • Gerald
  • Taken for 1 to 6 months
  • April 12, 2023

Epclusa (sofosbuvir / velpatasvir) for Hepatitis C "I started taking Epclusa in mid-April 2019 for three months. Within a week of starting the medication, I noticed a major drop in my energy level which continued throughout the duration of the drug course. Prior to starting Epclusa, I had been training for the BMO Marathon since December 2018 and was in incredible shape, as confirmed by my peers. However, I barely managed to complete the marathon and lost almost all my energy. This lack of energy has persisted to this day. Additionally, I was diagnosed with Polymyalgia Rheumatica. My lifestyle has drastically changed since being diagnosed in March 2020. I have been taking Prednisone and using Diclofenac 20 ml for all my aches and pains, just so I can at least walk. I now have high blood pressure, atrial fibrillation, osteoarthritis all over my body, and experience swelling every day, resulting in a low quality of life since taking Epclusa. I have also experienced depression, and aching, and gained 25-30 pounds. At the time of and prior to taking Epclusa, doctors, sports therapists, etc. all told me I was in better shape than most."

1 / 10
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  • Mr Re...
  • May 11, 2021

Epclusa (sofosbuvir / velpatasvir) for Hepatitis C "Took epclusa mid 2018 had no Hep c symptoms went to doctor for stomach ache. Test showed Hep c,no liver damage. Felt sick everyday taking Epclusa, my side effects are nausea headache fatigue body aches. Doctor said keep taking it. Hep c was cleared but now 3 years later I am so ill. I am in so much pain all over it hurts to move, I also have nausea, weight loss sleep the list goes on. I was not sick like this before Epclusa but it's ben like this since I took this medication. Been told I have fibromyalgia. All I know is this medication has ruined my life and I live with extreme pain everyday. If I could go back I would never have taken it."

1 / 10
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  • Say
  • Taken for 1 to 6 months
  • September 17, 2019

Epclusa (sofosbuvir / velpatasvir) for Hepatitis C "I was taking in the morning and that isn’t a good idea I felt sick all day long til about 4pm then I got a my energy back so I take it at night now. I do have insomnia but It’s getting better I started it on Aug 19 2019. The brain fog is getting worse as I take the medication. Drink lots of water or I get sick feeling and nauseous. My joint pain and fatigue is better. My eyes turn blue about 20 minutes after taking the medication and I get this odd feeling all threw my body after I take it I only say it’s like you feel the medication working on fighting the virus. I have the depression just start 9-10-2019. I can say I feel more there except when the Brain fog kicks in and I have serious worry it won’t ago away. My lymph node are swollen but they are going down. I’m glad I finally got to fight this virus I honestly Can’t wait for this 12weeks to be over."

6 / 10
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  • Jesst...
  • Taken for 1 to 6 months
  • September 26, 2017

Epclusa (sofosbuvir / velpatasvir) for Hepatitis C "Hi...So I took 12 weeks of Epclusa for genotype 3a (viral load-3million). The epclusa did do the trick to get rid of the hep c, however I did experience and still do experience side effects. While I was on treatment I experienced tingling, nerve pain, irritability, insomnia, ear ringing, etc. The ear ringing and ear issues remain a problem after 7 months off of the meds. I urge everyone to report side effects to the FDA. When I reported them to my doctor, I was told NO ONE else had those side effects...and I felt like I was crazy. The only way they will have a list of the accurate side effects is if they are reported to the FDA and GILEAD. This helps other patients not feel so alone. All in all it solved the main issue I suppose--"

8 / 10
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  • Geezer
  • Taken for 1 to 6 months
  • February 27, 2019

Epclusa (sofosbuvir / velpatasvir) for Hepatitis C "I started on epclusa 5 weeks ago. I was really nervous about side effects..as it turned out I didn't have any. Nothing. I have a viral load of 6 million. My fibroscan was a 4.6 so my liver is in better shape than even most people that don't have hep c. The beginning of fatty infiltration. Genotype 1a. My ALTs were 400 when I started, my 4 week ALT was 19. So far so good. Hoping for the best. Don't be afraid of this miracle. Genotype 1a."

10 / 10
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  • Fresh...
  • Taken for 1 to 6 months
  • October 8, 2019

Epclusa (sofosbuvir / velpatasvir) for Hepatitis C "I have been taking Epclusa now for 4 weeks and the main side effects are as they say, nausea (but haven’t actually thrown up just strong feeling) and extreme tiredness (you’ll sleep for a couple of days if you're not on a schedule). Your fluid intake needs to double with his medication!! I’ve been having diarrhea and it is very easy to get dehydrated which can cause other problems. Other side effects have been tolerable. I have Genotype 1a Chronic hepatitis C. And before taking this medicine I was very weak and the brain fog was so extreme it had me depressed. Now the cloud is starting to clear and my strength is coming back too. I too was nervous about taking it as we all are but it is worth it to me so I can have a fresh start. Good luck!!!"

6 / 10
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  • Skpp
  • Taken for 1 to 6 months
  • March 26, 2018

Epclusa (sofosbuvir / velpatasvir) for Hepatitis C "Ruined my life, feel like I'm dying everyday. Don't believe all these miracle stories you read. It's been over a year for me now and I'm getting worse everyday. Even the people that had no side effects when taking it are now showing up down the road."

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  • amandam
  • February 26, 2023

Epclusa (sofosbuvir / velpatasvir) for Hepatitis C "I'm on my last 27 days of this medicine. I was told no side effects except for maybe headaches. The longer I've been on it the worse it's gotten. I cry every day I have to take it, have migraines daily, can't sleep and when I do I get awful nightmares. I also am having bad abdominal pains, feeling freezing cold, muscle aches, weakness, shortness of breath, dry mouth, and feeling tired all the time and irritable, feel depressed, and emotionally unstable. I wasn't expecting this. I got blood work done today since the side effects have doubled just this last month. Had no issues feeling sick with my Hepatitis C prior but my levels were elevated so I decided to treat it. I think I made a grave mistake."

1 / 10
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  • Marc...
  • December 11, 2017

Epclusa (sofosbuvir / velpatasvir) for Hepatitis C "I'm a 62 year old man with Hep C type 2 b, I have had Hep C for over 40 years from IV drug use in the early 1970's I got sober in AA in 1977 and was diagnosed with Hep C shortly afterwards. I annually would get my blood work tested and in 2010 had stage 3 cirrhosis. In 2014 my insurance covered 90 day hep c treatment Sovaldi and Robaviran I had a difficult time, after 60 days hep c was undetected however 90 days after conclusion the Hep c returned! Fast forward to today I have 25 days left on the Epclusa 90 day treatment plan. I am still hep c detected from 1.5 million to 85 however Still Detected my doctor is not optimistic and I am frustrated but still trying. I am not giving up hope please pray for me! Thank you"

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  • Anonymous
  • July 2, 2020

Epclusa (sofosbuvir / velpatasvir) for Hepatitis C "I have now completed Epclusa!! I am 2 months post treatment!! I am still NEGATIVE!! So it does work!! I wanted to share my experience because some of you who are concerned about the side effects should be!! Yes I am treated but now the COVID is going around. I have been left with near to no immune system to fight anything else off!! I don't know for sure the epclusa did this. But I got a yeast infection during treatment. Probably from the epclusa and fought for 2 months to get rid of it. I ended up at my doctor. After test results from the past 3 months of blood work from 3 diff docs. I have found out my WBC is down to a 4 and has remained there sense I completed treatment. I am now susceptible to catching basically anything and having no immune system left to fight it off. During treatment I did not sleep for 3 months!! I lost 20 pounds was left with migraines every night. Night sweats and the list goes on. I am still weak everyday in my arms and legs!"

5 / 10
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Reviews may be edited to correct grammar/spelling or to remove inappropriate language and content. Reviews that appear to be created by parties with a vested interest are not published. This information is not intended to endorse any particular medication. While these reviews may be helpful, they are not a substitute for the expertise, knowledge, and judgement of healthcare professionals.