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How much does Epclusa cost?

Medically reviewed by Last updated on May 4, 2020.

Official Answer


The cost of Epclusa is roughly $78,078 for a 12-week course of treatment. Your cost might vary based on insurance or manufacturer-provided discounts.

For more information, see Epclusa Prices, Coupons and Patient Assistance Programs

Epclusa (sofosbuvir and velpatasvir) was the first direct-acting oral antiviral agent approved to treat all six major forms of hepatitis C virus (HCV).

Epclusa is indicated for the treatment of adult and pediatric patients 6 years of age and older or weighing at least 17 kg with chronic HCV genotype 1, 2, 3, 4, 5, or 6 infection:

  • without cirrhosis or with compensated cirrhosis
  • with decompensated cirrhosis for use in combination with ribavirin

Epclusa is taken once daily for 12 weeks.
For patients with decompensated cirrhosis, ribavirin is also included in the treatment regimen.

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