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How much does Epclusa cost?

Medically reviewed by Philip Thornton, DipPharm. Last updated on June 15, 2021.

Official answer


The cost of Epclusa (sofosbuvir and velpatasvir) tablets is roughly $US78,078 for a full 12-week course of treatment. Your cost might vary based on insurance or manufacturer-provided discounts. Epclusa is covered by most insurance plans.

For more information, see Epclusa Prices, Coupons and Patient Assistance Programs.

Epclusa was the first direct-acting oral antiviral agent approved to treat all six major forms of hepatitis C virus (HCV).

Epclusa is used to treat adult and pediatric patients 3 years of age and older with chronic HCV genotype 1, 2, 3, 4, 5, or 6 infection:

  • without cirrhosis or with compensated cirrhosis
  • with decompensated cirrhosis for use in combination with ribavirin

Epclusa tablets are used to treat patients weighing at least 17kg. Epclusa oral pellets have also been approved to treat children unable to swallow tablets.

Epclusa is taken once daily for 12 weeks.

Epclusa is a fixed-dose combination containing sofosbuvir and velpatasvir. An authorized generic version of sofosbuvir and velpatasvir tablets was launched in 2019. It is available from Asegua Therapeutics, a subsidiary of the company that also makes Epclusa. At the time of the launch of the generic, the list price for it was $US24,000.


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