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Sofosbuvir / velpatasvir User Reviews & Ratings (Page 5)

Brand names: Epclusa

Sofosbuvir / velpatasvir has an average rating of 7.8 out of 10 from a total of 402 reviews on Drugs.com. 66% of reviewers reported a positive experience, while 12% reported a negative experience.

Reviews for Sofosbuvir / velpatasvir

  • Hano
  • July 31, 2019

Epclusa (sofosbuvir / velpatasvir) for Hepatitis C "I just finished my first month. Although I haven’t gotten my blood work yet I’ll share side effects. I wasn’t really coached on a lot and was told time of day you take it, day or night doesn’t matter. Well it does. Dr said a lot of people have more problems if taking it at night. Did for me at least. I ended up in the ER on night three from uncontrollable vomiting, ear ringing and migraines that woke me in the dead of night (all 3 nights). I switched to morning and had to be put on zofran for nausea and ibuprofen is an every day thing. My liver aches randomly and never did before. The only symptoms I have now are migraines and tiredness. I must also note I am *tapering off methadone so I’m more moody, anxious already and everything is heightened. Didn’t really consider the effect it’d have on me doing both but my GI doctor wouldn’t stop pushing treatment on me. But also, I’m happy I did it and hopeful. Beginning was just a little tough"

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  • Mareb...
  • Taken for less than 1 month
  • October 24, 2019

Epclusa (sofosbuvir / velpatasvir) for Hepatitis C "I’m on my fifth day on Epclusa. I’m having a sharp shooting pain up the side of my neck. This happens randomly. Feel like my heads inside a fishbowl and general weakness. Not intolerable but not good. Now I’m reading reviews talking about how the symptoms can go on long after the medications have stopped. How worried should I be?"

6 / 10
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  • Candie
  • Taken for 1 to 6 months
  • January 17, 2019

Epclusa (sofosbuvir / velpatasvir) for Hepatitis C "I've had hep c since 1994 and in 2010 I did the interferon and it damn near killed me and then two years ago I did the vicaire pack and it made my body swell up so bad that I had to be admitted into the hospital five different times for for five days at a time. So I just started the epclusa I am two months into it and I am undetected. At first the only side effect I had was nausea but now I'm extremely tired and I'm having a lot of pain around where my liver sets at front side to back but other than that the medication is working great. I think I got about a month and a week left something like that I'll be done with my treatment March 1st. I've been on it since the end of November. I would highly recommend this medication for Hep C patients this is the third one that I've tried and the only one that I've had success with so far"

10 / 10
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Frequently asked questions

  • Brigid...
  • Taken for 1 to 6 months
  • July 8, 2018

Epclusa (sofosbuvir / velpatasvir) for Hepatitis C "Let me say when I was first put on Mavyret. Within 3 days I had the first psychotic episode of my life.....side effects they don't mention. Epclusa was fantastic though. Day 1, I could feel the medicine hit and I could also feel when it was metabolized a few hours later. I felt high day 1 but after that not really. Honestly maybe some mild relaxing effect. My first bloodwork came back viral load undetected and subsequent tests the same. I am done with the medicine now. Overall I had such mild side effects it is hard to say that they even were side effects. I felt really tired for about 3 days after completing the medicine. Maybe a few slight headaches. I made sure to drink 90 oz of water a day and took the meds with food in the evening. These definitely helped curb side effects. If you feel sick at all drink more pure water and take the meds with food."

10 / 10
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  • Will
  • Taken for 1 to 6 months
  • February 26, 2020

Epclusa (sofosbuvir / velpatasvir) for Hepatitis C "Started taking drug a month ago. Mild headache, a bit hard to sleep for a couple weeks. Felt very emotional for about a week, but that went away . All in all very little side effects compared to interferon, which I had to stop prematurely due to anger from the drug. Really gotta drink a bunch of water on this one. Dry mouth is helped with OTC biotene mouthwash . When I wake up I swish with that and it helps. Cheers!"

9 / 10
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Are you taking this medicine?

  • Greg
  • Taken for 1 to 6 months
  • June 15, 2018

Epclusa (sofosbuvir / velpatasvir) for Hepatitis C "Wanted to update my first post the Epclusa for me has been awesome some fatigue and I have ringing in my ears (tinnitus?) but this has been mild. I have 18 days left to go, my numbers are good with no sign of hepatitis C :) I knew I had it for long time but was not insured and the price was prohibitive so I just lived with it. I had no idea how much of a mental burden that was until it was lifted. I am feeling healthy and free. If this available to you and you're on the fence just do it! To the people who are struggling god bless and Do Not Give Up! Greg"

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  • Jewel...
  • Taken for less than 1 month
  • February 17, 2017

Epclusa (sofosbuvir / velpatasvir) for Hepatitis C "I was diagnosed in May of last year, only because my Dr wanted to "rule out" HepC but instead, I was one of the many "un-lucky" baby boomers that tested positive. I have Type 4 and I have/had no symptoms or indication of the virus except the positive blood test. I was also diagnosed with MALT Lymphoma at the same time. I completed radiation therapy for the cancer in Dec 2016 and waited for the HepC treatment until the effects of radiation had passed. I started Epclusa 2 weeks ago and I've had 0, none, nada side effects. In fact I'm feeling pretty darn good! I've been worried that it's not working since I'm feeling nothing but seeing that several people on this forum have had no side effects and complete cure makes me very happy!"

9 / 10
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More FAQ

  • Central...
  • Taken for 1 to 6 months
  • June 19, 2017

Epclusa (sofosbuvir / velpatasvir) for Hepatitis C "I am 1/2 way thru my 12 weeks. The side effects I've had are , headaches almost daily mainly in the evening. Most of my joints have discomfort/pain in my upper body. These issues are tolerable by all means. I do get exhausted easily. I did my first blood test last week and it appears that the virus is gone. I am getting anemia according to the test as well. So far none of these side effects are horrible just annoying. Keeping the prayers going for us. Will update more later."

9 / 10
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  • Eller...
  • Taken for 1 to 6 months
  • May 6, 2017

Epclusa (sofosbuvir / velpatasvir) for Hepatitis C "Hi I'm 51 F hepC type2 I just started taking the epclusa I'm 8 days in. I was expecting to be sick from it but, NO!! First day I felt less fatigue. Less pain. Not having any bad side affects, a little more gas and I feel a little irritated & not to be gross but noticed my stool looked dark green. I'm very pleased with the lack of side effects and hope it continues to be the same through treatment and of course that it's working and rids my body of this horrible virus. I pray for all of us every night that we get cured. I'll update when I do my blood work on week 4 . God bless everyone"

10 / 10
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  • Xjunk...
  • Taken for less than 1 month
  • July 11, 2018

Epclusa (sofosbuvir / velpatasvir) for Hepatitis C "I have hep c genotype 2b viral load over 10 million I started epclusa 4 days ago. I was really excited as for the first two days I had absolutely no side effects . Now relentless over production of stomach acid. My stomach is on fire and I feel like I wanna throw up all the time. I pray this goes away. I was an iv drug user for over 20 years and an alcoholic. I walked away from both of those deadly habits. Now I just wanna get rid of this horrible virus."

10 / 10
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  • Marlena...
  • February 22, 2017

Epclusa (sofosbuvir / velpatasvir) for Hepatitis C "I have hep c genotype 1 and I've had it for many years I assume. Found out 13 years ago but suspect to have had over 20. I have wanted treatment for many years but raising a family and homeschooling my children I just couldn't imagine feeling like I have the flu for a year. I'm so thankful for this medicine. I've had headaches and tiredness some nausea but I also have many great days with lots of energy. I have 29 more days to go and I'm so thankful and excited about having this wonderful opportunity to get rid of this and only having to pay 5$ copayment. I am 53. Today is 2/22/17"

9 / 10
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  • Truther
  • Taken for 1 to 6 months
  • November 17, 2022

Epclusa (sofosbuvir / velpatasvir) for Hepatitis C "Lipase levels raised 11 months after completion of Epclusa, creatinine levels high, triglycerides high, and LDL high. Thrombocytopenia developed.Severe abdominal issues after completion of this medication so I don’t think at this point the benefits of using Epclusa were worth the long lasting side effects.I never had any issues during 25 years of HCV until I took the Epclusa. ."

1 / 10
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  • Stormy
  • Taken for 1 to 6 months
  • April 19, 2019

Epclusa (sofosbuvir / velpatasvir) for Hepatitis C "After 3 weeks on Epclusa and no Hep C virus detected. First 4 days had brain fog, mild headaches and muscle cramping. I'm in the 9th week I feel pretty good. Ringing in the ears has started. I go to the gym to help with cramping. Eat every few hours and drink plenty of water."

8 / 10
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  • 88_lbs
  • Taken for 1 to 6 months
  • March 26, 2023

Epclusa (sofosbuvir / velpatasvir) for Hepatitis C "I originally went to see a doctor that was recommended to me by two friends. My problem was with my breathing, but the doctor worked in an infectious disease clinic. I just wanted to get a prescription for an inhaler that I had found helped. The doctor put me on an antibiotic called moxifloxacin, which I don't recommend to anyone. Very weird nightmares. When the doctor asked about past medical history, I said I had seen a doctor 14 years earlier who diagnosed me with Hep-C but told me I was in the 10% who had it but it wasn't active. This new doctor told me that there was no such thing and began pushing me constantly to go on a program to cure Hep C. Not trusting these newer prescription drugs, I was reluctant, but because of his constant pushing, I finally agreed. I took Epclusa along with the moxifloxacin, and everything started to change. I went from 120 lbs in the first month and 2 years later I'm now 88 lbs. and can barely function. Big Pharma is paying docs to push poisons. Stay away!"

1 / 10
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  • H j g...
  • Taken for 1 to 6 months
  • August 12, 2017

Epclusa (sofosbuvir / velpatasvir) for Hepatitis C "I did the 12 week treatment of epclusa. I am geno type 2. I started with 12,000,000 million I am now hep c free. I have one more blood test left at the 3 month blood test. anyway, hear lately I have been feeling bad headaches, a rash, nauseated and I'm just not sure what could be going on. Has anyone else had side effects even after taking the meds. During the treatment it wasn't terribly bad and I had some really good days as well."

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  • Star
  • Taken for less than 1 month
  • November 11, 2019

Epclusa (sofosbuvir / velpatasvir) for Hepatitis C "Week 2 of epculsa. Severe headches that do not go away no matter how much water I drink. Tired a lot. Have to work so I'm doing my best. Avioding caffeine helps but I'm still dizzy and weak. Having strange dreams and mood swings. But I want to be cured so I'm keeping in close contact with my doctor and praying it gets better."

8 / 10
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  • Never...
  • Taken for 1 to 6 months
  • July 25, 2019

Epclusa (sofosbuvir / velpatasvir) for Hepatitis C "June 8th 2019 began Gilead Epclusa HEP C undeterminable genotype (a first) Probably acquired 30--50 years ago, never had any sickness, and never tested. April--May 2019 test show Cirrhosis , had been drinking for 6 years up to Jul 4th, 2019. QUIT DRINKING I HAVE ESOPHOGEAL Varices quit smoking I have had NO noticeable side effects, But now not hungry as of end of July. My recent blood tests show normal levels of AST ALT Bilirubin , PT inr, PT, FE binding. all good. I already had Tinnitus from working as a roadie for 3 piece power bands in the 60-70's. All in all me going to die of liver disease may have been circumvented. I prefer old age Kaiser Health helped me and so far Epclusa too"

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  • blessed
  • Taken for 1 to 6 months
  • January 2, 2020

Epclusa (sofosbuvir / velpatasvir) for Hepatitis C "I have geno type 3a, I just started my second month of epclusa. The first week I was really tired but it was manageable, no headache, no nausea, now in my second month, I have no side effects and feeling great just had my four week blood draw and looking forward to the results i will update soon.."

10 / 10
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  • Queen...
  • Taken for 1 to 6 months
  • March 31, 2022

Epclusa (sofosbuvir / velpatasvir) for Hepatitis C "Before I started taking Epclusa I fainted and gotten a concussion when I went to the hospital I was diagnosed with Hep C. I am currently still taking Epclusa I'm on my 3 rd month of taking the medication. I've been experiencing lack of appetite and lack of sleep. One day I went about 72 hours with only 4 hours of sleep between the days. Went 3 days without eating and I'm on day 4 still no appetite. So have to force feed myself in order to keep myself from feeling more side effects, like headache and weakness. I find myself crying randomly time to time for the smallest of things. Haven't worked since I physically feel like I cannot keep myself together in order to work a shift so I can't wait until I complete my treatment and hopefully can go back to my normal self."

4 / 10
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  • Joe...
  • March 1, 2017

Epclusa (sofosbuvir / velpatasvir) for Hepatitis C "I finished taking epclusa in November 2016 after it was found that I still had hepatitis C genotype 3 even after I was treated in 2005 on an interferon ribavirin regimen for 26 weeks. Just two days ago I received the news from my infectious disease doctor that Epclusa did not work that I still have been found positive with the hepatitis C virus. For my wife and I this is very sad news and we are at a loss now as to what to do. My doctor is at a loss and he has no clue on what to do next and I am reaching out to anyone that is reading this if they have known anybody that has taken this new drug and it has failed them what were the next steps that they took. "

1 / 10
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  • cory...
  • Taken for 1 to 6 months
  • February 21, 2024

Epclusa (sofosbuvir / velpatasvir) for Hepatitis C "Hi, I'm on my last month of Epclusa and I thought I was the only one to experience these severe side effects! Since I started taking the medication, I itch like crazy and now have a rash on my leg. The stomach issues, forget about it, and the headaches, I've never had such bad headaches in my whole life. The fatigue and tiredness are unreal; my boss has had to take me home because my body would just not do anything! So, as for having hep C is uncanny, let alone having to deal with it. I would not recommend this drug by any means, especially if you have other issues with your liver and or other organs already."

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  • Skipp
  • December 7, 2016

Epclusa (sofosbuvir / velpatasvir) for Hepatitis C "Its been ABSOLUTELY TERRIBLE!!! The first week, whole body shaking. Had to start anxiety medicines. Headaches. Urinary tract pain, bladder pain since day 3, it is going on week 7 with this pain. Will be glad when it is over!!!"

10 / 10
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  • janessa
  • August 14, 2017

Epclusa (sofosbuvir / velpatasvir) for Hepatitis C "I have been fighting hep c for six years first when I was 51 I almost died from interforon and riboviron. OMG don't do it I know now we have so many better medications that will cure it. I was on epclusa for a month showed no virus and I panicked went off back at the end of Feb. Recently I went for blood work to find no virus this is four months after I went through treatment please pray it's over and I am cured Doctor said if it stays that way for three more month my chances are really good! I will keep in touch and pray for all of you."

8 / 10
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  • Sail
  • June 15, 2018

Epclusa (sofosbuvir / velpatasvir) for Hepatitis C "Had hep c 2b viral load 6 million. From the first day through the 12 week regimen I had no side effects. Actually felt great the whole time before starting was tired all the time lost weight and just felt bad all the time. Took my last dose May 2nd will take another blood test in August am praying it will be negative!"

10 / 10
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  • Free
  • September 8, 2017

Epclusa (sofosbuvir / velpatasvir) for Hepatitis C "I was diagnosed with Hep C and chronic Cirrhosis stage 3 a day after my 62 Birthday. I have been in recovery from Alcohol and Drugs for over 32 years but was IV user in 1974. Total surprise and shocked. I felt fatigue this last year, had some discomfort in my stomach area and some nosebleeds as well as headaches. I have always been healthy and this was out of the ordinary for me. I have been on Epclusa for 6 weeks and feel so much better. Very minimal side effects of headache and joint pain as well as sweating specially when in direct sunlight. I am so pleased with this treatment and thankful every day when I take the medication. Co-pay of $5.00 is amazing."

8 / 10
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Reviews may be edited to correct grammar/spelling or to remove inappropriate language and content. Reviews that appear to be created by parties with a vested interest are not published. This information is not intended to endorse any particular medication. While these reviews may be helpful, they are not a substitute for the expertise, knowledge, and judgement of healthcare professionals.