Roflumilast topical for Plaque Psoriasis User Reviews (Page 2)

• Ano...
• Taken for 1 to 6 months
• June 26, 2025

"Palmoplantar psoriasis - I only apply this cream on hands, heels, and elbows. My insurance covers it (first it was denied, but my doctor insisted, and it was approved). I pay $0. It started working within weeks and greatly improved the miserable condition of cracked heels and fingers. Unfortunately, if I stop and skip days, it returns. The middle of my palms do not heal completely. And it's been months at this point, so I'm not sure Zoryve treats this condition, maybe it just makes it tolerable. Side effects: itchy skin, and I noticed urinary tract related changes like pinkish color of urine sometimes. I don't know what happens if I stop using it - will psoriasis return with a vengeance?"

• gan...
• Taken for 6 months to 1 year
• May 6, 2025

"Have been dealing with psoriasis for years. Over that time, I've been prescribed several different medications. Zoryve is the first medicine that has actually worked for me. Within 3-4 days of beginning treatment, my plaques were fading and were completely resolved within 2 weeks. Amazing. Other creams I've used were petroleum jelly-based, and I had to wear sacrificial clothing and stay off the good furniture. This is not a problem with the Zoryve. To date, I have not had any noticeable side effects."

• Sle...
• Taken for less than 1 month
• March 5, 2024

"The medication started working immediately but I had insomnia from the first day! Can’t take anymore"

• Loi...
• Taken for 1 to 6 months
• May 30, 2024

"Redness and itchiness gone in 2 days. The best medication I have used. I would highly recommend."

• Anonymous
• Taken for less than 1 month
• June 1, 2024

"Stopped itching greatly. Redness disappeared. The only thing that has worked in over three years of treatment. It’s been like a miracle"

• drz...
• Taken for less than 1 month
• July 17, 2023

"Used only for five days. Initial results are dramatic; much better than with calcipotriene/betamethasone and without steroids. See improvement in these five days. Can't speak yet to longer usage."

• Sam...
• Taken for less than 1 month
• December 20, 2023

"It's a miracle! It changed my life. I am so thankful to whoever invented this."

• Anonymous
• Taken for 1 to 6 months
• September 25, 2024

"I have been using Zoryve as a solution to extreme genital itching. It works extremely well for 24 hours. As advised, it does cause mild diarrhea."

• Joa...
• Taken for 1 to 6 months
• October 19, 2023

"So far very good although not 100%, it does relieve the level of itchiness associated with this disease."

• Kat...
• Taken for less than 1 month
• November 10, 2024

"Immediate results. Cleared completely. Has not returned. I’m grateful."

• Mom...
• Taken for 1 to 6 months
• July 20, 2023

"It took a while but it is clearing my plaques. I'm very happy with it. I haven't had any negative side effects."