Pramipexole and Vomiting: What Users Say

• kas...
• March 17, 2009

Pramipexole for Restless Legs Syndrome "I took Mirapex for moderate RLS for about a year, and it worked like a charm. Then I began to develop side effects bad enough to force me to quit. Eventually, within 30 minutes of taking Mirapex at night, I would experience severe nausea and vomiting that would last for hours."

• Jos...
• Taken for less than 1 month
• September 11, 2019

For Restless Legs Syndrome "The first and only night I took pramipexole for RLS was so bad. I went to bed immediately after taking it. I get nervous taking new meds, so I thought I could just sleep through any mild side effects. I woke up 2 hours later with nausea, vomiting, slurred speech, and weakness. My boyfriend found me on the floor having extreme muscle spasms. He thought I was seizing. I spent the rest of the night sweating and weak. I’m not saying it doesn’t work for others, just be very cautious, make sure someone is home with you when you take it for the first time."

• Anonymous
• October 31, 2015

For Restless Legs Syndrome "I took this drug for the first time last night for my RLS. It was the worst night I have had in a long time. I was hot and sweaty all night, I threw up twice and only got a couple hours of sleep. The headache I have is terrible. I will not be using this again."

• Anonymous
• August 17, 2010

Pramipexole for Restless Legs Syndrome "I took Mirapex for a couple of months with my severe restless leg syndrome. It seemed to help, but I would wake up in the middle of the night and in the morning before work and have severe nausea and vomiting. I am now taking Requip, and it has been doing the same thing."

• Afj...
• Taken for less than 1 month
• May 6, 2020

Pramipexole for Restless Legs Syndrome "Unfortunately, this medication caused extreme nausea, dry heaves, and bloating. It did help my RLS, but I could not tolerate the severe nausea and dry heaves."

• Anonymous
• Taken for less than 1 month
• May 4, 2023

For Restless Legs Syndrome "Awful. It gave me vomiting and dizziness, and it didn’t reduce any symptoms of RLS."