Pramipexole Alternatives Compared

For Restless Legs Syndrome: Completely knocks out my RLS like a charm. My RLS had been getting worse due to my SSRI treatment so my doctor prescribed Pramipexole in a relatively small 0.125 mg dose when needed before bedtime. “When needed” is a tough decision because, from what I’ve read, the drug could take up to 3 hours to kick in. But, for me, I have normally found relief in less than an hour. The problem is that I feel like a zombie the next day. Drowsy, cloudy head, sluggish for most of the day after taking it. I’ve started breaking the tablets in half to take down the dosage even more. It still works but the side effects are still there. I’m currently searching for another path towards RLS relief with a different medication.

For Restless Legs Syndrome: Pramipexole works well but the only negative I would mention is in my experience it takes 90-120 minutes to take effect. This can become VERY frustrating if I feel the RLS becoming active and I haven't taken my medication yet. It can be a long time before I feel any relief!

For Restless Legs Syndrome: After 18 with RLS, I visited a doctor and got a formal diagnosis and medication. 0.25Mg Ropinirole (worked like a miracle cure initially) and building up to 2Mg after 2 months. started 2Mg and twice within 5 days I had collapsed/passed out/fainted. Therefore I am now on 0.5Mg twice a day - dinner and bedtime. It is hit and miss - two reasonable sleeps per week - 5 awful evenings and nights. Can't sleep during the afternoon any longer as RLS dominates my legs almost immediately when lying down. Progressive syndrome (RLS) and for life possibly and building a tolerance to Ropinirole - you wonder where this will go next / end up! All my sympathies for those out there with RLS - it is so unknown/misunderstood.

For Restless Legs Syndrome: I’ve had restless leg syndrome for about 30 years guessing!! Tried a lot of products but ropinrole seems to be the top of the list §!! My legs starts moving around 8pm most of the time if I’m watching tv or sitting down I have to get up and move I started with 0.25 twice a day now I’m on 1 mg!! Since last year not a year yet!! They were working wonderful but now and then they seem to be moving again. It gets so discouraging sometimes !! Soon I will check with my doctor. I may have to up it again a little !! The worst sometime I get weird dreams not pleasant at all but not all the time. I also get nausea but when I lie down it seems to pass off!! I take ginger chews seems to help !! Hope this helps someone !! Hope there is a cure for this sometime in the future !! I am 64 yrears old I would not be able to do without ropinrole or I would be up all night long !! Thank you!! For allowing me to share!!!

For Restless Legs Syndrome: I have had restless legs for over 50 years. It started when I was expecting my 1st daughter. I was told it was common in pregnant women but mine has NEVER let up - in fact has gotten worst over the years. I tried drinking quinine water until that was banned, it helped some but not much. I also 'held up the wall' with stretching exercises. I started taking ropinirole about 10 yrs on the advice of another person who called herself 'the queen of restless legs', I was given 1mg and told I should start taking 1/2 pill per day, increasing it weekly until I got 'results' - that one could take as many as 8 pills per day! Well, the 1/2 pill worked just fine for several years - I now take 1 to 2 per day depending.

For Restless Legs Syndrome: I have had restless legs syndrome for 30 years that I can remember. I have been on Requip for 15 years. Before it was approved for RLS. I was in a clinical trial for it then was able to get a script for it as it was approved for Parkinson's. RLS treatment varies on intensity of it. It only gets worse. I am up do 4 mg a day. The combination of what works is a moving target. I have tried it all. Requip is no longer helping me as it was. Once RLS starts I am screwed in to a night of living hell. I take Ambien to help but that is no longer helping.