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Pramipexole User Reviews & Ratings (Page 4)

Brand names: Mirapex ER

Pramipexole has an average rating of 6.7 out of 10 from a total of 243 reviews on Drugs.com. 56% of reviewers reported a positive experience, while 27% reported a negative experience.

Reviews for Pramipexole

Commonly mentioned side effects
  • gbe...
  • August 10, 2015

Pramipexole for Restless Legs Syndrome "I have had RLS for 25 years, and within the past two years has gotten much more uncontrollable. Ten years ago, I took Requip for a while, but the drowsiness during the day was a bother, and the RLS wasn't much improved. Last month, I started on Mirapex, and the relief from RLS was almost immediate. I'm currently taking .250 mg, two hours before bedtime. The only bothersome side effect has been some increased urination urges during the night. I haven't noticed any problems with dizziness, but I do have occasional Benign Positional Vertigo anyway, so it certainly isn't any worse. Overall, I would say Mirapex has done the trick."

8 / 10
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27 Report
  • H6H...
  • September 3, 2017

For Restless Legs Syndrome "I was prescribed this drug in April 2008 by a consultant neuro for RLS. I was not told of the side effects as my meds came in blister packs! I spent £130,000 due to compulsive shopping (yes, it is a side effect)! I was forced to set up an Individual Voluntary Arrangement (IVA), it ruined my life. I was a different person, it destroyed me. In the end, my marriage fell apart, I lost my home, £300,000.00, and my self-respect. Please, please be very careful on taking this drug, as I know I'm not the only person to suffer."

1 / 10
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21 Report
  • MJC...
  • March 18, 2010

Pramipexole for Restless Legs Syndrome "I have been taking Mirapex for a number of years for RLS. I originally took 0.125 mg once a day. After a few years, it was increased to 0.125 mg twice a day as my symptoms were rather severe. I have remained at the same dosage since then and have developed no side effects to the medication. I would seldom be able to sleep except for this medication."

10 / 10
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34 Report

Frequently asked questions

  • Ano...
  • August 2, 2011

Pramipexole for Restless Legs Syndrome "I have suffered from RLS and PLMD for years. The last few years, I've been taking Sinemet, which worked great in the beginning but gradually lost its effectiveness. I was up to 3 pills a day, and the RLS was worse than ever. My neurologist just started me on Mirapex, and it is incredible. One pill at night, and I get a good night's sleep. I'm also not getting the RLS during the daytime anymore. I haven't felt this good in a long time! No side effects either."

10 / 10
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29 Report
  • jds...
  • Taken for 6 months to 1 year
  • May 16, 2013

For Restless Legs Syndrome "I had suffered from restless legs syndrome periodically for many years. Then, suddenly, I was getting RLS every night. The weird thing, to me, is that I also had the feelings in my arms, but certainly not as frequently as the legs. After weeks of trying to reposition my legs, ignoring it (impossible!), I finally went to my doctor. I took my first dose that night, and haven't had symptoms ever since. I read up on the long-term usage and am a little concerned about it. I'll cross that bridge if and when I cross it."

10 / 10
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26 Report

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  • Ghm...
  • Taken for 2 to 5 years
  • March 14, 2018

Pramipexole for Parkinson's Disease "The Mirapex ER saved my sanity! I had restless legs so bad, mainly at night, and my legs would jump so hard I would come close to falling off the bed. It was terrible. Mirapex ER came to my rescue. I have been on it for several years and am thankful for how it works."

10 / 10
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17 Report
  • DCM...
  • February 13, 2017

For Restless Legs Syndrome "I wanted to cut my legs off. I was willing to sit in a wheelchair for the rest of my life versus living with the agony from RLS, which at the time felt like I was telling my doctor a fib. When Mirapex came to Canada, I went straight to him and said, put me on this NOW. I would go weeks without any half-decent sleep, if any at all. Now, if I don't take my 3.50 mg a day, I know it. BUT I also just (today) got out of the hospital from the psych ward, third time. Each time has gotten worse. Suicide, uncontrollable actions, grandiose ideas, lack of sleep, and not from RLS, heart palpitations, eyesight blurry, confusion, short memory, forgetfulness... and of course, compulsive gambling/shopping! SOMETHING ELSE HAS TO WORK! now..."

10 / 10
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19 Report
  • Mem...
  • Taken for 1 to 6 months
  • July 23, 2016

For Restless Legs Syndrome "This medicine is a miracle! OMG! It nearly has made my RLS disappear, only had it 2 times in 4 weeks since I have been on it! Before, I was getting RLS around 2-3 times a day! I couldn't go to a movie or sit to watch TV, car rides were miserable. Since being on this medication, I have been to a movie and 3 concerts without RLS! I have tried Requip and Gabapentin, and neither of those worked. I am so happy with this med! I take 0.50 once a day at night. I think the reason I have had RLS the 2 times in these 4 weeks is that I didn't take it at the same time those 2 nights, I took it later than usual! All in all, I am very happy with this, I am taking the generic."

10 / 10
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21 Report
  • jal...
  • February 20, 2010

Pramipexole for Restless Legs Syndrome "Since taking it for RLS, I have not had a single problem with my legs or arms trying to run a marathon while I try to sleep. The only problem I have is it makes me dream like crazy. I sometimes wake up and almost think the dreams were real. It is very strange, and it happens almost every night. I have gotten used to it though. For the relief it has provided me, the dreaming is worth it."

9 / 10
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32 Report
  • waz...
  • Taken for 2 to 5 years
  • July 4, 2015

Pramipexole for Restless Legs Syndrome "I have had RLS since I went through my last growing spurt at the age of 14. I am now 35 and have tried every over-the-counter drug, herb, and supplement known to man. Nothing helped. I tried Mirapex, and though it did not always fully work, it worked sometimes, and if you have RLS, you know that sometimes is pretty awesome. I started taking tramadol for back pain, and for the last year, my RLS is completely gone. The only problem is that tramadol was like taking cold medicine and downright horrible most days, and the withdrawal can be life-threatening, in my opinion. As we all know, any opiate taken right before bed completely cures RLS. But if you stop taking it, your RLS will be 100 times worse, of course, the time spent sleeping is worth it!"

6 / 10
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27 Report
  • Ric...
  • Taken for less than 1 month
  • March 4, 2019

For Restless Legs Syndrome "Suffered undiagnosed sleep disorder for 20+ years. Light, poor-quality sleep. I sleep so soundly now that I need to put my alarm on for the mornings. Spouse says that she has never seen such a dramatic change in my sleep quality."

10 / 10
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16 Report
  • Anonymous
  • September 16, 2010

Pramipexole for Restless Legs Syndrome "After suffering from RLS for over 30 years and trying numerous medications, to include Quinine Sulfate, this WORKS. Loss of sleep has diminished, as well as the attitude to go along with it. I can't believe that after all the doctors I saw, this one diagnosed it without me telling him. I was sitting in the office, and my legs were jumping. That afternoon, I tried the Mirapex, and presto, problem solved. No side effects I know of, dose is 0.5 mg 2x per day, some days not needed. What a relief."

10 / 10
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30 Report
  • ste...
  • September 17, 2010

Pramipexole for Restless Legs Syndrome "Military doctors originally put me on Klonopin for my restless leg syndrome. The medication was a total godsend! My only noticeable side effect was dizziness if I stood up too fast. Once we retired from the Army, however, new doctor, new medicines. I got stuck with a neurologist with a 'complex,' who told me I could take Mirapex and have nerve damage testing, or I could just have the nerve testing and go without. Great. So I took the Mirapex. Over about six weeks, I've gained weight (not normal for me), forgotten LARGE amounts of things. I sleep LOUSY and still have the 'twitches.' The doctor finally listened and put me back on Klonopin but didn't warn me about switching from one to the other. I've now been awake for over 24 hours, only catnapping in 15-minute increments."

2 / 10
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29 Report
  • Anonymous
  • January 5, 2010

Pramipexole for Restless Legs Syndrome "I have had disruptive RLS for all of my life. A couple of years ago, it got intolerable. I tried Requip first, but it made me exceptionally tired the next day. Mirapex works quite well, allows me to not move and get agitated, and I feel fine the next day."

9 / 10
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28 Report
  • Pea...
  • Taken for 5 to 10 years
  • January 16, 2015

For Restless Legs Syndrome "Pramipexole has changed my life! I have suffered with restless legs syndrome since I was about 25 years old, and I am now 78. After starting this medication, I have been able to get a good, full night's sleep. As a result of sleeping well, I have a lot more daytime energy. I occasionally have bouts of RLS, but with the consent of my doctor, just increasing the dosage for a few days will get me through these episodes. Sometimes I don't increase the dosage during one of these episodes but take a hot bath, which helps. When I have been without the meds for a couple of days, not even a hot bath will help. This has been a WONDERFUL medicine for me. It literally has made my life full again."

10 / 10
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24 Report
  • Reo...
  • September 8, 2015

For Restless Legs Syndrome "I have taken Mirapex an average of 4 nights per week for about 11 months. I have no restless leg when I take it at least an hour or so before the usual onset (for me, bedtime). I am so very happy to have found such a simple cure to something that has plagued me and caused me problems for thirty years. Now I can even travel in an airplane or car in the evening and at night with no restless legs...a huge change for me. I am thrilled. I love it. I have not noticed any side effects."

10 / 10
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  • blo...
  • December 13, 2010

Pramipexole for Restless Legs Syndrome "I agree with it working. I had Rest Legs Syndrome and didn't sleep well for a month. After being put on other medicines that didn't work, the doctor decided to give me Mirapex. Oh my. I sleep every night and wake very clear and not groggy. I truly do not know where I would be if it weren't for this medication."

10 / 10
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26 Report
  • KAT...
  • October 25, 2008

Pramipexole for Restless Legs Syndrome "I have been using Mirapex for almost a year now. Before that, I used Requip. I take a half dose twice a day. A single dose a day does not make 24 hours. This makes 12-hour shift work tolerable as far as the RLS."

10 / 10
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31 Report
  • Nik...
  • Taken for 1 to 6 months
  • October 1, 2022

"I was suffering from depression with panic attacks and anhedonia, and all SSRIs I tried helped only partially, having no impact on the anhedonia. After trying bupropion and aripiprazole (augmentation) and not tolerating them, I had pramipexole added to my SSRI, and to my surprise, it helped a lot. It increased my motivation and my libido, without making me anxious or very restless."

9 / 10
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7 Report
  • Che...
  • November 22, 2019

For Restless Legs Syndrome "I have been on pramipexole, generic for Mirapex, for about 15 years. The only side effect is a bit of drowsiness now and again. I am very pleased with how this medication works. Previous doctors have had me on drugs that would push my RLS even harder as the drug wore off. Now my new general practitioner wants me to try extra iron, magnesium, and zinc to see if that can replace taking this drug. Trying that, but I am happy to stay on Mirapex because it works for me!"

10 / 10
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  • Bil...
  • Taken for 1 to 2 years
  • February 22, 2022

Pramipexole for Parkinson's Disease "Terrible side effects included a gambling compulsion. Felt compelled to buy stacks and stacks of lottery tickets despite never being into gambling. Lost impulse control, leading to some terrible decision-making that I couldn't stop even as I saw how it was negatively affecting my family. Building a life for decades seemed to be lost almost overnight... out of my control. And the only change was the use of Mirapex."

1 / 10
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  • mjb...
  • Taken for 5 to 10 years
  • June 17, 2017

Pramipexole for Parkinson's Disease "Diagnosed in 2010 at 46 years old - I have been using Mirapex ER 0.75 mg once a day for several years with minimal issues/problems - It can have a lot of side effects, so it is not for everybody. Okay, so I've seen a few ghosts along the way... (at the time, I was at a higher dose of 1.25 mg per day) - I haven't seen any since lowering the dose to the current 0.75 level. Although you can get the fast-acting non-ER version, you really need the ER version to keep it in your system longer to receive the benefit of it. For me, it helps to minimize the cramping I get in my right foot. My insurance will not cover this drug. I ran across this Mirapex assistance site (Eagle Pharmacy / Lakeland, FL) where I can get Mirapex ER for $30 a month without insurance."

8 / 10
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21 Report
  • Var...
  • June 28, 2009

Pramipexole for Restless Legs Syndrome "I have a 90-year-old home care patient who was started on Mirapex 4 days ago. She suffered with restless leg syndrome and leg cramping nightly. She informed me that since starting this medicine, she has felt great and slept soundly for the first time in years."

9 / 10
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27 Report
  • Kat...
  • Taken for 2 to 5 years
  • December 1, 2020

For Restless Legs Syndrome "I have been on pramipexole for about 3 years, starting out at one half of .25 mg tablet. Soon that did not work, and I had to increase it to .25 mg and then .50 mg. This drug definitely helps my RLS, but I cannot take it. I have gained almost 30 lbs, and I have not changed my diet. My restless legs are generated from my antidepressants and low iron ferritin. I have now decided to get off the antidepressant, even though it helps me a lot, but I cannot tolerate the RLS anymore. I know my road to feeling better will be difficult, but I've got to do it."

1 / 10
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10 Report
  • aks...
  • September 28, 2017

For Restless Legs Syndrome "Pramipexole can cause fainting. I had been quite pleased with the effects of pramipexole during the 3 months I had been on it. However, for about 3-4 weeks prior to my hospitalization, I just felt out of sorts. I began to notice a feeling of being lightheaded. One morning I bounced out of bed - standing up too quickly - and woke up a few moments later having fallen against a wall. I didn't enjoy the resultant scrapes. (Neither did the wall.) After a visit to the ER followed by two days of very impressive detective work, the very fine doctors informed me that pramipexole - also known as Mirapex - was the culprit. Take this drug seriously. It works quite well but at a potential cost. Hope this benefits you all."

1 / 10
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16 Report

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