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Phenazopyridine and Upset Stomach: What Users Say

Brand names: Pyridium, Azo Urinary Pain Relief, Uristat, Azo-Standard, Uricalm, Uristat Ultra, Prodium, Azo-Septic, Eridium, Baridium Re-Azo Azo-Gesic Preferred Maximum Strength Urinary Pain Relief Preferred Urinary Pain Relief Uro-Pain …show all brand names

Upset stomach: mentioned by 12 users (6.3%)

Based on user experiences from 189 Phenazopyridine reviews, the following table shows the most commonly mentioned side effects.

All user comments are moderated by Drugs.com. Each review is verified for relevance and screened for inappropriate content. Side effects are user-reported and not clinically verified.

nausea 11.6%
upset stomach 6.3%
vomiting 5.3%
itching 4.8%
pain 4.8%
burning 3.7%
dizziness 3.7%
headaches 3.2%
dark urine 2.6%
abdominal pain 2.1%

Reviews for Phenazopyridine

Showing 12 reviews tagged with "upset stomach". Clear filters to view all 189 reviews.
Commonly mentioned side effects
  • Anonymous
  • Taken for 10 years or more
  • November 24, 2014

Phenazopyridine for Interstitial Cystitis "I have used this for years off and on during flare-ups of IC. Besides making my urine a 1970s throwback color of orange, over the past year or two, Azo Standard has upset my stomach. Not enough of a problem to do without it, but enough to avoid food. It does work to rid me of the urgency and burning sensation."

9 / 10
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61 Report
  • Tok...
  • Taken for less than 1 month
  • January 12, 2020

Phenazopyridine for Dysuria "Man, this does nothing for me but turn my urine orange. It made my stomach hurt extremely bad. Like, it made a knot in my stomach where I couldn’t move. I had a heat flash and all. It was horrible. Seriously."

1 / 10
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28 Report
  • Lee...
  • January 8, 2016

For Interstitial Cystitis "I am a 57-year-old female, suffering from interstitial cystitis for the past 5 years. First and foremost, DIET is key: no orange juice, grapefruit, spices, cranberries, and cranberry juice is the worst for I.C. sufferers. Cranberry is great for urinary tract infections, but NOT for I.C., also, Azo is NOT for I.C., it has cranberry in it. Only Uristat works for I.C., unless, of course, you are allergic to it or have an upset stomach. Take 4 saltine crackers before taking, I have a very sensitive stomach, and this works for me."

10 / 10
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33 Report

Frequently asked questions

  • Det...
  • November 29, 2015

Phenazopyridine for Interstitial Cystitis "This did nothing for the cramping and pain. In fact, I had horrible GI gas and stomach issues while taking it. I thought I had a stomach virus, but when I stopped the Pyridium, the stomach distress went away."

2 / 10
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35 Report
  • Det...
  • November 29, 2015

Phenazopyridine for Interstitial Cystitis "This did nothing for the cramping and pain. In fact, I had horrible GI gas and stomach issues while taking it. I thought I had a stomach virus, but when I stopped the Pyridium, the stomach distress went away."

2 / 10
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35 Report

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  • pin...
  • Taken for less than 1 month
  • June 22, 2022

Phenazopyridine for Dysuria "IDK, I came on here to see if anybody else felt nauseated for the whole day after taking these, because that’s how I feel. My stomach hurts sooo bad, and I just know it’s this medication. IDK, it’s not for me. It helped me with my UTI pain, though."

4 / 10
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11 Report
  • Anonymous
  • August 2, 2009

Phenazopyridine for Dysuria "Having high sugar levels, I tend to get urinary tract infections more than others. Not having health insurance, I found myself having to wait until payday to make it to a doctor. I have used Uristat in the past and found it to work wonders, so I used it again. It is not a substitute for an antibiotic, but it will help. Follow package directions to avoid an upset stomach."

9 / 10
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27 Report
  • Mar...
  • Taken for less than 1 month
  • December 7, 2017

Phenazopyridine for Dysuria "I took the drug and followed Dr.'s instructions. First day, I began to have an uneasy stomach, and the following day, I vomited food and a pill. After four days of stopping taking the pill, I'm still having an uneasy stomach. I have also had leg cramps at night. This medicine is not for me."

1 / 10
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14 Report
  • Mot...
  • Taken for 1 to 6 months
  • December 9, 2019

For Interstitial Cystitis "Azo is the only thing that helps IC flares, or I get a UTI. Good news is it really does take the pain away after a little while. But for me, it's not without consequences. Those consequences or side effects include stomach ache and lots of vomiting if I don't stuff myself with food before taking it. And I don't mean a normal meal, I have to actually stuff my stomach with food. Sometimes I'll think I'm full enough, take the Azo, and half an hour later realize I was wrong. So, make sure you eat a lot of food before you take this medication."

7 / 10
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10 Report
  • Ano...
  • September 24, 2016

For Dysuria "Took the medicine last night for the first time. Didn't notice any changes, except that it made me sleepy. This morning I awoke to find that I had a major headache, terrible stomach cramps, all-over body ache, and confusion. I would not recommend this product, as it also gave me really weird dreams."

1 / 10
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10 Report
  • frs...
  • Taken for less than 1 month
  • August 28, 2012

For Dysuria "After 2 doses, I noticed a significant difference in my urinary tract symptoms. It does upset your stomach and make you feel nauseous. Luckily, the doctor will only put you on this medicine for 3 days before the antibiotics start to kick in."

8 / 10
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6 Report
  • Abi...
  • Taken for less than 1 month
  • January 2, 2022

Phenazopyridine for Dysuria "Major migraine and upset stomach from using Uristat."

1 / 10
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Reviews may be edited to correct grammar/spelling or remove inappropriate content. Reviews appearing to come from parties with a vested interest are not published. This information is not intended to endorse any medication and should not replace the expertise and judgment of healthcare professionals.