Pegfilgrastim and Allergic Reaction: What Users Say

• G M...
• March 3, 2017

For Neutropenia Associated with Chemotherapy "I am not sure how effective the shot was, but I'm giving a low rating due to a severe allergic reaction. I had my first chemo on a Monday and received the shot at 3 pm the following Wednesday. By 5 pm, my feet were burning, a rash swept up my whole body. My heart was racing. I spent the evening in the ER. I needed a shot of epinephrine and was hooked up to an IV. I will not be having the shot after my second round of chemo this Monday."

• Lil...
• Taken for 1 to 6 months
• September 14, 2022

For Neutropenia Associated with Chemotherapy "This drug is overused and used unnecessarily! There's no need to raise people's WBC count into the 30's! 2nd dose caused a supposed allergic reaction - it felt like my head, neck, back, and forearms were on fire! Like 3rd-degree sunburn! Temp dropped to 94 degrees - hypothermia?! There's no antidote! Ride it out with Benadryl and Tylenol! If our blood work is good, why do they make us get it? I believe my side effects were from too high neutrophil/WBC count! It didn't have anything to do with the 'drug' itself! By the way, too many WBC causes hair loss too! I refused the 3rd shot, and I feel so much better this time! Hardly any side effects from A/C chemo at all! Last dose on day 2, hair was falling out in globs! No Neulasta this time, and I have zero hair loss! Coincidence? Makes me wonder which drugs cause hair loss?"

• Jol...
• February 21, 2011

"I had a severe allergic reaction to Neulasta! Within two hours of the shot, my tongue and mouth swelled, making speech difficult, I had red, puffy hives from my neck down. I was rushed to the ER, where I was put on an IV of adrenaline and Benadryl and a couple of other medicines to control the allergic reaction. I spent the night in the ER room while the doctor on duty said to my husband, NEVER in all his years of practice has he ever had to pump that much medication to control an allergic reaction! Neulasta also contains the E. coli bacteria, and for over a year, my doctors have been unable to get rid of a bladder infection I keep having recurrently! The bladder infection is the E. coli bacteria, which, after being treated with antibiotics, only returns within weeks."