Xolair User Reviews & Ratings (Page 4)
Xolair has an average rating of 7.5 out of 10 from a total of 229 reviews on Drugs.com. 67% of reviewers reported a positive experience, while 18% reported a negative experience.
Reviews for Xolair
- Jan...
- December 10, 2018
For Urticaria "I have had chronic urticaria for about 10 years. Tried acupuncture, which helped me reduce my allergy meds by half but not all the way. Then started Xolair 3 months ago. It helped with hives, and I was able to reduce my allergy pills to just 2 Zyrtec a day. However, I have a host of negative side effects: rash on my face that won’t go away, severe irritation of the lining inside my mouth, inflamed lips, and significant weight gain. I’ve decided it’s just not worth all these negative side effects, so I’m stopping Xolair."
- Sha...
- Taken for 1 to 2 years
- March 17, 2025
For Urticaria "It worked great in the beginning, a year ago. The longer I use it, it seems to be less effective. I've now had hives 24/7 for 3 weeks. No relief from itching, skin is bruised from scratching. I've experienced hair loss, a cough, and at times my tongue swells. I'm currently taking 150 two times. Dermatology doctor has increased it to 2 injections two times a month. March will be my first time to use this much. Further testing is being done now, March 2025, and it seems I may need to change medications. Testing is ongoing at this point. Along with Xolair, I've been taking antihistamines daily. It all helped in the beginning, but the doctor thinks I have something else going on."
Frequently asked questions
- What are the most common skin conditions? (with photos)
- What are monoclonal antibodies?
- Is Xolair an immunosuppressant?
- How long before Xolair starts working?
- WeN...
- May 14, 2011
For Asthma, Maintenance "I have been on Xolair since June 2009, and I can somewhat tell a difference. I don't use my rescue inhaler as much as I used to, and I don't get bronchitis as much. My maintenance medicines have not changed at all over the last few years. Still on the same doses and medicines. I have been using a lot more of Prednisone though."
- Jac...
- Taken for 6 months to 1 year
- May 8, 2023
For Urticaria "I have had chronic hives since they randomly appeared one day when I was about 8. I have been taking Allegra and Zyrtec for years, and that has helped a bunch, but I still got flare-ups now and then. Finally, my doctor recommended Xolair. At first, it seemed to work, at least for the first two weeks. Then my hives started to flare up, covering my whole body and becoming unresponsive to any medicines. My doctor increased my dosage, but that has only made them worse. I have them every day. They are more painful and itchy than before I started taking Xolair. Side effects: for me, I have noticed that I am constantly tired. I used to be a night owl, and now I can barely make it past 9 p.m. I sleep 12 hours and wake up feeling exhausted. I have noticed some bone and muscle pains too. I feel a lot weaker overall. And I’m only 20. In conclusion, this drug might work for some, but for me, it only made things worse."
Are you taking this medicine?
Your review helps others make informed decisions.- Anonymous
- Taken for 6 months to 1 year
- July 9, 2012
For Asthma, Maintenance "This medication given bi-weekly, 3 injections each visit (150 mg), has been life-changing. Having been in an induced coma to save my life, followed by a tracheotomy, and in and out of the hospital many times last year, I needed this. I went from a lung rating of 8/10 (serious) to 0.8 in 4 visits. My lungs have vastly improved, and my Prednisolone (steroid) is stabilized. Fortunately, I qualify for funding as a government patient. I only had one reaction - with the very first dose - a rash. Now I take an antihistamine before I leave home for the injections."
- Dav...
- Taken for 5 to 10 years
- January 6, 2017
For Asthma, Maintenance "I developed allergies in my 30s and then asthma. Within 5 years, the asthma and allergies became severe, having anaphylaxis and systemic reactions to medicines and foods, while inhalants caused severe asthma reactions. I saw 6 allergy specialists, and I was told there wasn't anything else they could do. I had an anaphylactic reaction to both allergy skin testing and an allergy immunolytics therapy injection. Finally, in 2008, an allergist recommended Xolair. After 4 months, I noticed the seasonal allergies and number of asthma issues decreased. I haven't had an anaphylactic reaction since 2010. I now just take Allegra daily and live a regular life."
More FAQ
- Does Xolair cause hair loss?
- Does Xolair cause cancer?
- How does Xolair work?
- How long can Xolair stay out of the fridge?
- nan...
- Taken for less than 1 month
- June 28, 2017
For Urticaria "I've had hives off and on since 2002. I am 52 years old, and I've been diagnosed with Hashimoto's and lupus. I was tired of hive breakouts and constantly taking Benadryl, so I decided to start taking Xolair. Within a half hour after the shot, my hands got red and itchy. I told the nurse, she seemed unconcerned. I got very tired, went home, and slept half a day! That night, I got three hives on my leg and arm. The next morning, I was achy all over and got dizzy with a headache. I report I also got some chest heaviness. I called the doctor, and he said it was not from Xolair. I can stop Benadryl, but he wants me to continue shots. So far, I can't stop Benadryl because I'm still itchy! I don't know if I should get the next dose because I don't want worse side effects. Want to eat again."
- Tre...
- October 31, 2016
For Urticaria "I developed hives and unknown swelling since I was 18. My life was miserable. I was always in the hospital. I hated it so much. I was so depressed all the time. I felt like I wasn't living. Xolair really gave me my life back. I have been on it for 5 months. So far, so good :) I wish I could hug whoever made this drug!!!"
- JFa...
- May 7, 2018
For Asthma, Maintenance "I have had a very positive response from these injections. I've just started my 7th month. From constantly taking Ventolin, being breathless, coughing, and unable to exercise, I am now back to normal, no Ventolin used in the last 7 months, where I used to use 5 to 7 Ventolin scripts a month. Feeling great."
- AJa...
- August 28, 2019
For Urticaria "In my case, the pre-filled syringes do not work at all! Have had 3 sets of shots so far (was not taking anything else during that time frame): - 1st set of shots (the vials), after 2 weeks, I noticed a 95-100% improvement in chronic dermatographism, a 100% improvement in the chronic itchy skin (no rash) symptom, and some improvement in other symptoms... but no improvement in chronic GI symptoms and chronic body swelling. - 2nd set of shots, they switched to the pre-filled syringes. Shots hurt a lot more than the vials/my Allergist's syringes. Then, after a few hours, had throat discomfort/pain/pressure which didn't go away till the next morning... and the pre-filled syringes did absolutely nothing and lost some of the improvement I had gained. - 3rd set of shots, strongly asked Allergist to switch back to the Xolair vials, which they did. Shots hurt a lot less, no throat discomfort/pain/pressure, and after a couple weeks, regained some of the improvement I had lost."
- Mad...
- November 16, 2017
For Urticaria "I was very hesitant to start this medication because of all the warnings I came across online. After 4 months on this medication, I can honestly say it has 100% improved my life. I had hives and angioedema covering most of my body. The pain and hives would come and go and change from day to day, but I was for the most part homebound because of it. I was taking Benadryl (like Tic Tacs), Zyrtec, Singulair, Fatidomide, and Prednisone for the really bad breakouts. Within the 1st week after the 1st shot, I saw significant improvement. Now I only have some breakouts right around the 28th or 29th day of the next shot that is due. I would highly recommend this medication for chronic urticaria."
- Enr...
- November 14, 2015
For Asthma, Maintenance "I've had asthma since childhood, and at 57 years old, my asthma attacks were so bad I tried everything. My allergist suggested Xolair. My asthma is under control. I feel great with regular injections twice a week. I thank my doctor and Xolair. If your asthma is bad, give it a try. God bless."
- Anonymous
- July 9, 2010
For Asthma, Maintenance "I've been taking the shots for 6 months now and have only had 2 episodes of mild asthma. Before the shots, I had severe asthma for 27 years and was on steroids for 27 years. Needless to say, my bones have suffered the consequences of steroids. I wish this drug wasn't so expensive. It saves lives. It changes lives, but most people can't afford it! Including myself. I was completely disabled from asthma, but Medicaid approved this drug for me for 6 months. It has made an amazing difference."
- Tul...
- Taken for less than 1 month
- September 15, 2019
For Asthma, Maintenance "Xolair was prescribed to treat my severe asthma and chronic urticarias, but after my first shot, I had an anaphylactic reaction. They brought me to the emergency room and I was able to go back home 5 hours later, but unfortunately, I had another delayed anaphylactic reaction and had to stay in the hospital for 3 days, and during this time, I had 4 more episodes. I was excited about Xolair because I read so many positive reviews, and my doctors also told me that it was going to help me a lot. But it didn't work for me."
- PKa...
- March 19, 2018
For Urticaria "I have urticaria hives for almost 7 years. I have tried Zyrtec, Claritin, and all other medicines. No luck. Finally, I found Xolair. It really worked well for a while. I was amazed to have that injection every time. No hives, itching, redness. Yeah, I got what I needed. But after a year, I realized my elbow and palm were getting muscle pain and joint pain in fingers. And also, if I got a cold, it would take time to recover even if I had the cold and cough syrups. I used to have the cold for more than 10 days. Sneezing, coughing, runny nose. You can say, 'It might be allergies.' Yes, I tried Zyrtec for allergies also, nothing worked. Xolair destroys our immune system totally, whatever we built from our childhood. Sometimes, when you get a cold, people will have a fever tablet also for precaution. But after having the tablet only, they will feel fever. Same here, slowly you will be like an asthma patient after getting Xolair even if you don't have asthma. No Xolair. Avoid sugar whenever possible (sugar will lead to being itchy). Good luck."
- ROK...
- March 5, 2018
For Urticaria "I had experienced severe, frequent episodic urticaria for approximately two years. I'd been tested for allergies and spent a year working with my dermatologist attempting to isolate an allergen without success. He ultimately suggested we try Xolair. All symptoms were gone within 24 hours of the first Xolair injection (300 mg - 150 mg in each thigh subcutaneously). There were four treatments at four-week intervals followed by two 150 mg treatments at four-week intervals. There is no research to guide the decision of when to discontinue the drug and no incentive for the manufacturer to conduct the trials. I've not had an injection for 8 weeks and remain symptom-free."
- Gra...
- Taken for 1 to 6 months
- January 7, 2016
For Urticaria "I am 72 years old and have suffered from chronic urticaria for 18 months now, 24/7, and my antihistamines and prednisone are no longer helping. My doctor suggested that I try Xolair. I have had my second injections today and have had no decrease in my hives. I have read that it may take 2 or 3 months before it kicks in, but I was sure hoping that I would have some relief in the first month, especially because of the cost of this drug. I will continue for a couple more months to give it a fair chance."
- Gra...
- Taken for 1 to 2 years
- June 12, 2018
For Urticaria "This injection has done an amazing job eliminating CIU/DPU (chronic idiopathic urticaria/delayed pressure urticaria)! I have been getting 300 mg every 8 weeks for about a year and a half now with no side effects. I have been dealing with hives for about 8 years prior to Xolair, and prednisone was the only drug that would get rid of the hives."
- Dad...
- Taken for 6 months to 1 year
- September 17, 2018
For Urticaria "My daughter has chronic idiopathic urticaria and began taking Xolair about 9 months ago to treat the frequent and widespread hives that she was suffering with. Prior to taking Xolair, she would get widespread hives about once per week, and they would last anywhere from 1 to 3 days. Subsequent to taking Xolair, she has not had a single case of hives. So we are extremely pleased with our results."
- SCa...
- Taken for 1 to 6 months
- March 2, 2018
For Urticaria "I suffered from chronic hives for months with multiple attempts at different combinations of antihistamines. The condition only worsened. I went from being hive-free for short breaks to having hives covering 50% or more of my body constantly, day after day for months. Xolair has changed it all. I have been and remain completely hive-free. I got my first shot and had immediate relief. I had a couple of small hives that wanted to break through, but literally lasted a couple of hours and went away. They were hardly noticeable. Xolair has brought me back to the quality of life I expect."
- Anonymous
- Taken for 1 to 6 months
- June 21, 2016
For Urticaria "In early November 2015, I started breaking out in unexplained hives. It started with huge welts larger than my palm, and I'd get them all over my body, some small, some big. From my scalp to the bottom of my feet, welts have shown up, and my lips and fingers have swollen so badly. Xolair has made a marked difference for me. It hasn't completely cleared me up, but the amount of hives has dramatically decreased. I still get angioedema though, but I don't panic like when it first started happening. I'm hoping as time goes on 1 - the hives will just go away completely (haha we all wish for that, right?) and 2 - if the hives don't go away, the shot will continue to lessen the severity of the breakouts."
- ban...
- Taken for 2 to 5 years
- December 13, 2018
For Urticaria "I have been on Xolair since November of 2016. Overall, this has been a very effective treatment for me. Besides a few 1-2 month flare-ups, I have seen a significant improvement. Untreated (and during flare-ups), I break out in hives 2-3 times a day every day, frequently with swelling in my face, lips, hands, and feet. Xolair has decreased this to almost no hives."
- CKa...
- Taken for 2 to 5 years
- November 22, 2020
For Urticaria "Xolair has changed my life for the better, and I have been asymptomatic since starting monthly injections. I had chronic idiopathic urticaria (CIU) and angioedema for the past 20 years. I had been trying high doses of antihistamines, NSAIDs, acupuncture, basically anything to stop the itching and swelling. At one point, I was put on prednisone, only to have the CIU come back after tapering off. Then I worked with the doctor to test Xolair. It has worked amazingly well. I get injections once a month, and for the most part, am asymptomatic. I have no side effects. Sometimes before an injection, I will have itching, but the next injection quickly alleviates symptoms. Xolair has been transformative at changing my quality of life. I am so much happier and healthier now."
- Yo ...
- Taken for 1 to 2 years
- June 6, 2019
For Urticaria "I have had CIU (chronic idiopathic urticaria) on and off for about 20 years. I had a long span of many years where the hives disappeared, but then one day, they returned. I have been on Xolair for about a year, and it worked... until 2 weeks ago. Now I am having aggressive hives after having virtually none this past year. Xolair clearly worked when I started the medication, so I am sticking with it for now. I have zero side effects from Xolair. I am concerned it seems to have stopped working, however. I will have to do some research on vitamin D and CIU."
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For Urticaria "I've been experiencing breakouts for months. Have gone through everything everyone else has, so no need to rehash. I'll get to the point for those who are suffering. On January 23, 2017, I received my first injection of Xolair. In less than 24 hours, I was already experiencing some mild relief. It's been a full week, not one breakout of hives. It feels like I have my life back."