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Macrobid and Tiredness: What Users Say (Page 3)

Reviews for Macrobid

Commonly mentioned side effects
  • Lau...
  • March 7, 2015

For Urinary Tract Infection "I took my first pill of Macrobid last night, and it caused nausea, and it made me exhausted. I noticed when I was nauseous, I felt better if I ate something. It's like I constantly needed something in my stomach, but I felt miserable. I also had chills, so I'm guessing I had a fever. I'm about to eat a heavy breakfast and take my next pill, hopefully, this second dose goes okay. Otherwise, my doctor is getting a phone call first thing Monday morning."

1 / 10
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  • Clo...
  • October 9, 2016

For Urinary Tract Infection "I had a minor UTI. I just couldn't seem to clear it out of my system, so I got prescribed Macrobid. The first day I took it, I felt a little drowsy, but nothing major. The second day, dose two, I began to feel very drained and had no energy. I thought maybe I just needed sleep, so I tried to nap, but I just lay there in discomfort and exhaustion. I began to have cold/flu symptoms. I became very dizzy and nauseous. I felt like I was spinning. I was bedridden and cried from how bad I was feeling. It did help my UTI symptoms, but I am not sure if it's worth it."

3 / 10
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  • Clo...
  • October 9, 2016

For Urinary Tract Infection "I had a minor UTI. I just couldn't seem to clear it out of my system, so I got prescribed Macrobid. The first day I took it, I felt a little drowsy, but nothing major. The second day, dose two, I began to feel very drained and had no energy. I thought maybe I just needed sleep, so I tried to nap, but I just lay there in discomfort and exhaustion. I began to have cold/flu symptoms. I became very dizzy and nauseous. I felt like I was spinning. I was bedridden and cried from how bad I was feeling. It did help my UTI symptoms, but I am not sure if it's worth it."

3 / 10
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  • Lis...
  • Taken for less than 1 month
  • July 18, 2018

For Bladder Infection "Macrobid was by far my worst experience with a medicine. It was prescribed for my UTI. But after taking 2 pills only, I started feeling worse than before. My UTI symptoms were improving (which was great), but I felt sick. Extremely nauseated (I couldn't even drink water); had diarrhea episodes, it also lowered my blood pressure, so I felt weak and tired. I'll never take this thing again. I felt like I had been poisoned."

4 / 10
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  • Sab...
  • Taken for less than 1 month
  • September 13, 2018

For Urinary Tract Infection "I was prescribed this for a UTI because I have a high sulfa allergy. I took one pill and was fine with no problems, took it with food as prescribed and went to bed about 5 hours later. Woke up in the morning with my body aching so bad I felt like I had the flu. I was really spaced out, depressed, had diarrhea. It cleared up the symptoms for the UTI very fast, but I have to go to get a different prescription. I’ve had body aches all day and feeling so lethargic. I don’t recommend."

3 / 10
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  • Spa...
  • September 9, 2010

For Bladder Infection "I didn't even know I had a bladder infection, showed up in a urine test. So I guess it's working. I do feel tired after working out and exhausted later on in the day. On it for a week, twice a day, 100 mg."

8 / 10
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  • Spa...
  • September 9, 2010

For Bladder Infection "I didn't even know I had a bladder infection, showed up in a urine test. So I guess it's working. I do feel tired after working out and exhausted later on in the day. On it for a week, twice a day, 100 mg."

8 / 10
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  • Cur...
  • October 3, 2016

For Urinary Tract Infection "I'm allergic to sulfa and penicillin, so my doc prescribed Macrobid. The first time I took this medicine, I felt fine besides some nasty nausea. I didn't take the last 3 pills because of it, but my UTI went away almost immediately. This time, I feel horrible. I felt good after the first 2-3 doses, but now after I take it (3rd day), I am weak, I feel like it's hard to breathe, and my stomach burns/hurts so bad I can't stand it. It also makes me very tired and out of it/woozy. The burning during urination has gone away, but I feel worse than what I did with the UTI. I hate to stop it early, but I fear I may end up in the hospital if I don't. It's not a bad med, just hit or miss side effects. I say try it out though. It's worth that much at least."

5 / 10
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  • Mad...
  • Taken for less than 1 month
  • November 13, 2019

For Bladder Infection "If I could give Macrobid a score of a negative 1 million, I would! Because of this antibiotic, I have been sick for 4 days. Had to take a trip to the ER and had 2 bags of IV fluids put in me and a chest x-ray. All for a simple bladder infection. As soon as I took the first pill, I was instantly sick. I ended up taking 3 of my doses and stopped. I have chest pain, nausea, headaches, and very tired. Bladder infection gone in 24 hours, but I’m sick as a dog. I’m so angry this pill was prescribed to me. By the looks of it, I don't think it should be on the market!!! Do not take! Drink some cranberry juice."

1 / 10
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  • den...
  • Taken for less than 1 month
  • July 3, 2021

For Urinary Tract Infection "I just had a course of Macrobid, and I can honestly say I have never felt as poorly. I had a raging fever, temp 39.03, palpitations, and chills. Loss of appetite and exhausted. I didn't finish the course and feel better 48 hours later. I wouldn't recommend these tablets to anyone."

1 / 10
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  • Ale...
  • June 5, 2021

For Urinary Tract Infection "Terrible experience with this med. I had side effects of exhaustion to the point of being unable to move and major stomach upset. Had to switch to Bactrim. It might be fine for some people, but I had an awful experience. Didn’t even help my UTI either."

1 / 10
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  • Ano...
  • October 29, 2018

For Urinary Tract Infection "Prescribed 7 days for severe bladder infection. Made me very tired, bothered my stomach and quit it after 3 days. Had a scratchy throat on the 3rd night, restless sleep. Was in bed all day on the 4th day. Then started getting a cold, head cold on the 5th day and at bedtime, could hear crackling in my lung/chest area. Never had that before. Will never take this again. Hoping no damage done to my lungs."

2 / 10
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  • Anonymous
  • Taken for less than 1 month
  • January 31, 2018

For Bladder Infection "About 30 minutes after taking the pill, I felt like I had the flu. (Feverish, chills, achy joints, terrible stomach pains, headache, heartburn, and pure exhaustion.) Within the hour, I had to go to bed. I do have to say that I woke up the next day feeling great! I waited until I got to work because I didn't want to take the pill and drive. I spent the rest of the day at my desk feeling the same as the night before. When it was time to drive home, I felt okay, and the symptoms from my infection were clearly getting better. I'm now on day 4, and I've gotten into a routine that helps. I take the pill at 10 pm after I've put my kids to bed and do what I have to do for the night so that I can go right to bed and skip feeling like crap all night. Then I take it again at 10 am, about an hour or so after I get to work in the morning. I eat Greek yogurt right before taking the pill and a few crackers or a Nutrigrain bar right after, and that has definitely helped with the stomach cramps and heartburn!"

8 / 10
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  • Mac...
  • Taken for less than 1 month
  • July 15, 2018

For Urinary Tract Infection "On Macrobid, I had nausea, was so tired, and had a headache. I made it 6 days. Don’t ask how. I hardly have the energy to walk, no appetite, and everything hurts. I’m not finishing it and hoping for the best."

4 / 10
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  • Jan...
  • Taken for less than 1 month
  • March 18, 2018

For Urinary Tract Infection "I have foolishly taken Macrobid twice for the same infection. It seems to clear it up, but actually, it reappeared within two weeks. Both times had a severe reaction. High fever alternating with chills. No energy whatsoever. Sleeping all the time. Terrible headaches. Nausea. Unable to eat, no appetite whatsoever. Dry mouth, no saliva to the extent my mouth stuck together overnight and my lips cracked, and it felt like I had a trout pout my mouth was so swollen, tongue fuzzed up and feeling like sandpaper. These drugs are cruel. I will tell my GP I cannot take them ever again. I went downhill from getting the drugs, at first, I imagined it was the infection coming out or maybe worse, I have cancer, but I really should have read these reviews-the negatives are spot on. I too was referred to the ER, who probably weren’t aware of the side effects or that they could be so bad."

1 / 10
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  • Mom...
  • Taken for less than 1 month
  • June 30, 2021

For Urinary Tract Infection "Upon my 1st and 2nd dose, I was lethargic. I could barely keep my eyes open. I had nausea and just all around didn't feel right. But it helped with my UTI after the first dose. On my 3rd dose now and not feeling the past symptoms... though my tummy has been very bloated throughout taking this med. I don't know if I'd take it again, considering these side effects."

5 / 10
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  • Sue...
  • June 14, 2021

For Urinary Tract Infection "BEWARE: I’m glad that some of you had a good experience with Macrobid. It does seem to be really good for a stubborn UTI. My UTI is better after 3 doses; HOWEVER, after dose 2 (with food), my hands and feet swelled and began to have significant joint pain. Then came leg pain, bad back pain (kidneys?) and a headache in the back of my head. Became SOOO tired and weak. After dose 3, crazy, out-of-control chills, increased weakness, and hours of inability to take a good breath. All night long I had terrible trouble breathing, could barely walk to the bathroom. Was in bed for 18 hours. Got up for 5 hours feeling only slightly better and went back to bed for 12 hours. Now day 3 since first dose, and I can’t do anything. Breathing is better, but now diarrhea has set in. Just beware of the beginning of symptoms so you can be prepared to stop taking it."

3 / 10
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  • lem...
  • Taken for less than 1 month
  • November 11, 2022

For Urinary Tract Infection "Not going to lie, the first 24 hours of taking this sucked. I felt absolutely exhausted and like I had the flu. But then I felt so much better. Like others, I was terrified to take this. But it really did work for me. The first day of suckiness was worth getting the UTI to go away."

8 / 10
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  • Boa...
  • Taken for less than 1 month
  • September 22, 2018

For Urinary Tract Infection "On day 4 of this medication. First couple of days I was tired and had a headache. Could be from the meds or the UTI. Now that has gone, but now I have some aching down the backs of my legs. Could be the meds or the heels I wore yesterday."

8 / 10
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  • Nau...
  • Taken for less than 1 month
  • July 4, 2018

For Urinary Tract Infection "I had an extremely painful UTI and was prescribed Macrobid. Took it with food on the first day and was fine, then woke up at 5 a.m. on day 2 (today) vomiting bile. Repeated at least 5 times in a couple of hours. I am making sure to keep my stomach full at all times today as when I am not constantly eating something, the nausea comes back. I am also very tired. I can at least say that my UTI symptoms are clearing up, but I am not looking forward to taking this drug for a whole week."

2 / 10
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  • Mac...
  • Taken for less than 1 month
  • March 1, 2022

For Urinary Tract Infection "I must be allergic to this. Aches, shivering, headache, exhaustion. VERY rough night. Last time had pain and burning on the soles of feet. Dr. thought I was nuts and told me to take a Covid test, which was negative. I have never been allergic to anything before. Weird. It is now marked on my chart to steer clear of this drug for me. Giving a 2 because it DID help my UTI. Now on Cipro, we'll see....."

2 / 10
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  • Lau...
  • Taken for less than 1 month
  • October 22, 2021

For Urinary Tract Infection "This pill sucks, but it sucks less than a UTI! My side effects: nausea and total fatigue, stuck in bed, no energy, a bit depressed. It is definitely the Macrobid because I wake up feeling fine and then take the pill with yogurt/breakfast and then I feel horrible. But when I have a UTI, I am stuck on the toilet, which is much worse than being stuck in bed. The only thing annoying to me is that after the UTI goes away, I'm still slightly sick from the Macrobid for days."

5 / 10
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  • Sal...
  • Taken for less than 1 month
  • August 1, 2021

For Urinary Tract Infection "The side effects I have experienced are as follows: - Stomach pain - Nausea - Vomiting - Tiredness - Overall ill feeling - Some diarrhea. In conclusion, this is the worst antibiotic I have ever experienced, and I am still recovering after 48 hours of not taking it. 1 in 100 people will suffer horrible side effects."

1 / 10
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  • Ban...
  • Taken for less than 1 month
  • May 21, 2018

For Urinary Tract Infection "Macrobid is absolutely dreadful. It got rid of my infection fast, but it actually came back, and the side effects were horrible. It made me wobbly, shaky, and made me so sick I kept almost throwing up. It made me very, very tired, but I could barely sleep. I will not be taking this medicine again."

1 / 10
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  • scr...
  • Taken for less than 1 month
  • November 11, 2018

For Urinary Tract Infection "First day of taking Macrobid made me super tired at work, I felt like a zombie. The second pill gave me a huge headache, and at night I got a huge cough and my throat itching, kinda like when I get a cold. I was coughing so much and waking everyone up. I just hope my UTI clears up after this. I am on my 3rd day out of 5. I won't take Macrobid again if I get another infection."

3 / 10
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Reviews may be edited to correct grammar/spelling or remove inappropriate content. Reviews appearing to come from parties with a vested interest are not published. This information is not intended to endorse any medication and should not replace the expertise and judgment of healthcare professionals.