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Macrobid and Tiredness: What Users Say (Page 2)

Reviews for Macrobid

Commonly mentioned side effects
  • Anonymous
  • January 18, 2012

For Urinary Tract Infection "I have been on Macrobid for 3 days now. I feel so nauseated. I'm so tired, and I can't eat or drink anything, except for a little water, without getting sick. It gives me a horrible headache, and I feel so weak. I am also allergic to sulfa medications (Bactrim), so the doctor gave me this."

3 / 10
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  • Cha...
  • Taken for less than 1 month
  • June 7, 2019

For Urinary Tract Infection "Awful drug. Took Macrobid for 3 days for UTI, where I couldn’t eat as I felt so sick, slept nearly all day, every day, as it made me so tired. I’m on the progesterone contraceptive pill, it has interacted with that, and I’ve had a period for 3 weeks nonstop since taking these antibiotics (after 5 years of no periods). Three weeks on from taking these, I have been depressed the whole time, not wanting to get out of bed and felt teary, and everything was making me cry. I thought I was going insane as you don’t expect medication to still be affecting you 3 weeks after you have finished taking it!! Gave me twitches in my hands too! Need this medication out of my body ASAP!! Trying to take charcoal, probiotics, and milk thistle to recover my body from this awful drug!! Do not take it, ask for a general antibiotic instead, as it’s so not worth the side effects. I’d rather suffer from the UTI than ever take them again!!"

2 / 10
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  • Bum...
  • Taken for less than 1 month
  • December 23, 2012

For Urinary Tract Infection "I suffered severe headaches and nausea for hours from the very first dose and every dose thereafter. I would feel faint, overheated, extremely tired; I slept with the windows open and the heat off (it's winter). Four days of taking Macrobid, I began to have loose stools and severe muscle aches and neck stiffness. I began to have a sore throat and a dry cough on day two. After stopping, within 24 hours, I began to itch severely. I've been off of it for 48 hours and I still have a headache and I use Benadryl for the itching. I was given Levaquin in one dose, then Macrobid 100 mg two times a day for 10 days by the ER doctor. But my primary doctor thought it was overkill and should have just used the Levaquin."

3 / 10
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Frequently asked questions

  • Anonymous
  • August 14, 2010

For Bladder Infection "Took for a bladder infection. Felt better after a day or so, but got extremely nauseated, even taking it with a snack. It also makes me so tired, all I want to do is sleep. I have stopped taking it, and it feels like I am getting the same symptoms back. I am allergic to sulfa drugs, and this is what the doctor gave me."

4 / 10
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  • Anonymous
  • Taken for less than 1 month
  • January 5, 2020

For Urinary Tract Infection "This drug was fine at first. By the second pill, it seemed as if my UTI was gone. If you don’t take this drug with TONS of food, it will mess you up. This drug also gave me severe stomach gas and diarrhea every morning. It also increased my appetite so much when I woke up that I had to eat something immediately or I felt sick. I really did not like being on this medicine. It messed up how I felt and just made me super tired and uncomfortable. I hope I never have to take it again."

2 / 10
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  • Jco...
  • November 17, 2019

For Urinary Tract Infection "Cleared up the UTI pretty quickly. But on the second day, I started to have some side effects: nausea, upper abdominal and back pain, feeling very weak and tired. Eating a larger meal with the pill seems to help a little. Not the worst medication, but not great either."

5 / 10
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  • 816...
  • August 14, 2016

For Bladder Infection "Was prescribed this antibiotic for a bladder infection at emergency care. Doctor said there were few side effects when I asked - was hesitant to take it because I'm very sensitive to antibiotics, but was assured this was the best medicine for me with the least side effects. Wrong! By day 2 I was totally lethargic, feeling very irritable and running a low-grade fever on and off. Thought temp was from bladder infection. Finished 6-day course, went to my doctor for a urine recheck, and since my culture appeared clean, was told I could stop a day earlier. Two days off the medicine and I'm still feeling like crap, extremely tired and lethargic with a low-grade fever of 100.5. Feel like I have a minor case of the flu, but since reading other articles I believe it's from the antibiotic. Never again will I take this."

2 / 10
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  • Kri...
  • Taken for less than 1 month
  • August 4, 2019

For Urinary Tract Infection "I started this 11 hrs ago... Let me tell you, it has made me feel horrible. Dizzy, trouble concentrating, exhausted, my face feels odd, hot/cold, and I'm nauseous. I am terrified to take another dose. Unfortunately, my culture showed this antibiotic to be most effective. But there is no way I can take 5 days of this. I just looked up reviews and saw that I'm not the only one feeling this way. I have only had a bad reaction to Erythromycin (vomiting) many years ago. I don't recall an antibiotic ever making me feel this way before."

2 / 10
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  • Ash...
  • Taken for less than 1 month
  • August 31, 2022

For Bladder Infection "Started taking Macrobid last week, and after the first dose, I felt off. I ended up leaving work early that day because I had intense nausea, chills, and general lethargy. Later that evening, it had progressed to a fever, balance issues, and it's like I had no legs under me. Took one more dose, and it was the same issues. Decided to discontinue the meds, and the side effects went away almost immediately. But that didn't help the bladder infection. I started to think maybe it was the infection that had caused all of the side effects, despite not having any now. So I took another dose this morning. You guessed it, ALL of the side effects from before. So I contacted my NP who prescribed Cipro instead. My pharmacist says that the adverse reactions are pretty rare, but I can't imagine taking the full course of Macrobid. The nausea was the worst! I honestly felt terrible!"

1 / 10
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  • Anonymous
  • Taken for less than 1 month
  • July 21, 2018

For Urinary Tract Infection "I was prescribed this medicine for a possible UTI. Didn't work because I believe I have cystitis, but this was precautionary. Almost didn't take it because of the reviews! The only bad side effect I had was stinky gas and maybe a little tired. I don't understand how this drug has so many bad reviews. (Maybe people who have bad experiences are more likely to review something and the ones who have good experiences just move on with their lives.) Drink it with a glass of water and food. I was fine."

8 / 10
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  • Est...
  • May 9, 2019

For Urinary Tract Infection "I got a UTI and was prescribed this medicine. At first, when I would take it, it was fine. However, after the first day, I started to get extremely tired and would sleep SO MUCH. Then I started getting a bit of heart palpitations, but I disregarded it. After about 3 days in, I took it at night (with food, of course), and a little after, I started to feel TERRIBLE. I got heart palpitations, a fast heart beat, shortness of breath, and major anxiety. I knew it was this antibiotic since I was feeling just fine before taking it. I barely slept that night, and when I woke up, I still had the terrible symptoms, so I finally went to my doctor, and she took me off it, and we're getting my urine tested again to see if it went away. In just 3-4 days of taking it, I had such bad side effects, and it’s been a day since taking my last dose, and I’m still feeling sick."

1 / 10
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  • Kbr...
  • August 29, 2018

For Urinary Tract Infection "I'm in my 5th day of Macrobid. Really just wanted to review to ease some minds because I ran to the internet too when I was prescribed this medication (like I always do with new medicine). The only side effects I've had are some nausea/stomach upset, anxiety (I have health anxiety and was pretty shook up from the reviews, so could be that), tiredness, and my urine turned a dark yellow/fluorescent yellow. I'm 19, get UTIs a lot as I'm prone to them, and am on a 7-day course. I'm also usually pretty sensitive to medicine because I'm so in tune with my body. Basically, this drug is fine (for me). If you drink/eat before/after taking it, the nausea is dramatically reduced. I even talked to my nurse, and the majority of people do well on the medicine with little side effects (mainly upset stomach). This medicine has taken care of my UTI, no problem. By day 3, I felt normal."

9 / 10
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  • H R...
  • Taken for less than 1 month
  • June 30, 2017

For Urinary Tract Infection "This is the third antibiotic in 2 weeks used for a UTI. Yes, the drug has been effective in healing the infection. However, it would not be my 1st choice. I've had muscle pain in my legs and feet, exhaustion, insomnia, grotesque nightmares, weakness, unsteadiness walking, nausea, dry mouth with a taste of metal in my mouth."

9 / 10
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  • Joa...
  • Taken for less than 1 month
  • June 7, 2019

For Urinary Tract Infection "The doctor diagnosed me with a mild UTI yesterday and prescribed Macrobid. A few hours after taking it, I felt my brain wasn't fully functioning, very slow. After that, I was beginning to feel more and more nauseous, which ended up in full-blown violent vomiting, which was continuous for hours. Now it's the next day, and I have heart palpitations, a bursting headache, extreme tiredness, still can't hold anything down. I've never been this sick from any other antibiotic, and I only took 1 dose. The doctor prescribed me different antibiotics, I couldn't continue the Macrobid with these abnormal side effects. I never write reviews but thought to share my experience this time because of the severe side effects this medicine can have. It might work great for some people, but not for me."

1 / 10
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  • bnp...
  • Taken for less than 1 month
  • August 20, 2018

For Urinary Tract Infection "This is my first time leaving a comment on a drug on this website. I'm just here to relax anyone who gets prescribed this medication. This medicine did give me the chills, tiredness, joint pain, and nausea, but it did what it was supposed to do. Got rid of that same UTI that I had that just wouldn't go away, which is dangerous. I was given 2 rounds of Bactrim first. I felt very sick from the UTI anyway, so feeling off from the Macrobid made no difference. Be happy it isn't ciprofloxacin or any other fluoroquinolones you were prescribed, which is what these doctors try to push now when patients want a switch from the med that seems would work best after a culture test. Some of them don't know that the FDA put out warnings that it shouldn't be prescribed for conditions like this, for very serious reasons. You have been warned."

9 / 10
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  • Mis...
  • June 21, 2019

For Urinary Tract Infection "I was given the Macrobid medication for a UTI. I took the first dose with food before bed and woke up feeling okay. I took the second dose that morning and headed into work. On my way into work, driving, I began to get dizzy, I thought I wouldn’t make it in. I arrived, then I immediately left work-went home with a headache, nausea, diarrhea, dizziness, and body aches. I took another dose before bed to try and power through, then woke up the following morning unable to move, again with flu-like symptoms. My doctor told me to stop taking the medicine. And I will NEVER take it again. I am currently a day and a half off the antibiotic and still experiencing nausea, diarrhea, aches, and exhaustion. It is getting much better as time goes on, but I feel as if I wasted time on a medicine that made me even more sick when I should be UTI-free by now. My stomach is still so sensitive from this, so I cannot even go back on another antibiotic yet. Still have a UTI, missed three days of work, and feeling awful."

1 / 10
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  • mon...
  • September 19, 2015

For Urinary Tract Infection "Just finished 3 days of this for a UTI, and though it has worked for the condition, I feel terrible! Feel like I have no energy and like I'm going to pass out. Whole body aches! Just phoned my chemist, who told me this was quite common on this tablet, and I should feel normal in a few days. Shame it's my wedding anniversary today, as I just want to go to sleep all day. Won't take this one again, it's not worth it."

4 / 10
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  • Cee...
  • Taken for less than 1 month
  • December 8, 2020

For Urinary Tract Infection "I was prescribed Macrobid for a very painful UTI. I had taken it once before for the same reason but couldn’t remember how it made me feel. I was prescribed it twice a day for 7 days. This time it took a few days to begin working, and I was thankful to have also been given an analgesic to help with the pain since this didn’t resolve that. It made me feel incredibly bloated, tired, dizzy, and gave me awful stomach cramping and diarrhea. Somehow, all of this was still better than the UTI, though, and I am now 2 days after finishing the round of medication and feeling better. Overall, it seems to have its side effects, but if you’re able to tolerate them, it should be beneficial for infections."

6 / 10
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  • Cle...
  • Taken for less than 1 month
  • June 23, 2019

For Urinary Tract Infection "Horrible side effects! Oh my goodness. Just 2 days on this and I had to give it up. I had to hold onto the walls when walking, I was so dizzy. I also felt like I was going to pass out and vomit at the same time, and felt hot like I had a fever. Never again. The doctor then put me on cephalexin (Keflex brand), and no side effects except a little tiredness. P.S. D-mannose is amazing at preventing UTIs. Better than antibiotics. I had just stopped taking it."

1 / 10
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  • Wee...
  • July 27, 2016

For Urinary Tract Infection "By the end of day one (2 doses), I felt very tired. Day two, I woke up weak, fatigued, achy, but was advised to stay on Macrobid as the UTI symptoms had improved. As the day wore on (3 doses), I became increasingly tired, had no energy, a headache, a sensation of heart racing, and nausea. Another call to my provider, and they suggested I switch to Cipro. Before I could do that, an episode of nausea sent me to the bathroom. I passed out, hit my head, and ended up hospitalized. I would be very afraid of this medication, considering the other options."

1 / 10
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  • Wee...
  • July 27, 2016

For Urinary Tract Infection "By the end of day one (2 doses), I felt very tired. Day two, I woke up weak, fatigued, achy, but was advised to stay on Macrobid as the UTI symptoms had improved. As the day wore on (3 doses), I became increasingly tired, had no energy, a headache, a sensation of heart racing, and nausea. Another call to my provider, and they suggested I switch to Cipro. Before I could do that, an episode of nausea sent me to the bathroom. I passed out, hit my head, and ended up hospitalized. I would be very afraid of this medication, considering the other options."

1 / 10
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  • OVE...
  • Taken for less than 1 month
  • October 19, 2018

For Bladder Infection "This is the most awful antibiotic I have ever used. I took it for 3 days and could not handle it anymore, it made me dizzy, lethargic, tired, very spaced out, emotional, and caused bad anxiety. Never again."

1 / 10
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  • OVE...
  • Taken for less than 1 month
  • October 19, 2018

For Bladder Infection "This is the most awful antibiotic I have ever used. I took it for 3 days and could not handle it anymore, it made me dizzy, lethargic, tired, very spaced out, emotional, and caused bad anxiety. Never again."

1 / 10
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  • Goo...
  • Taken for less than 1 month
  • September 14, 2017

For Urinary Tract Infection "I had a UTI not too long ago, and I was prescribed Macrobid. I did not have any crazy side effects. Unfortunately, I get them frequently and just started a new round of Macrobid, and this time has been nothing but bad news. I am on day 5 of 7, and I have been extremely nauseous, dizzy, and tired along with sharp abdominal pain. The UTI isn't as severe anymore, but I feel like it hasn't been as effective and that it's still lingering. I made sure to eat a decent meal before and drink plenty of water, I think that it's just not reacting well with my system. I am definitely stopping after today and going to the doctor to figure out a new solution."

2 / 10
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  • Sic...
  • Taken for less than 1 month
  • May 5, 2019

For Urinary Tract Infection "I was prescribed this Macrobid antibiotic for a UTI. It has horrible side effects, really bad. The first day I took it, I had really bad headaches. The second day, I started to feel like I was dying, no joke. I wasn't sure what was causing it, so I kept taking it. Now, today is the 3rd day, and I feel so sick I can't even get out of bed. I have had to call into work twice now because I have no energy to do anything at all. This is the worst experience I have ever had on an antibiotic."

2 / 10
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