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User Reviews for Savella to treat Fibromyalgia

The following information is NOT intended to endorse drugs or recommend therapy. While these reviews might be helpful, they are not a substitute for the expertise, skill, knowledge and judgement of healthcare practitioners in patient care.

Savella Rating Summary

User Ratings
6.7/10 Average Rating
314 Ratings with 315 User Reviews

What next? Compare all 31 medications used in the treatment of Fibromyalgia.

Reviews for Savella

Dragonfly · Taken for 1 to 6 months July 8, 2019

"My neurologist took me off Cymbalta which was working and started me on Savella. I worked up to 100 mg. That night my heart rate skyrocket to 160 BPM. I went to emergency room thinking I was having a heart attack. I Googled the side effects of Savella and saw tachycardia on the list. I’m warning myself off. Really scary to think that doctors do not consider crossed side effects of multiple medications. Learned my lesson."

Farris · Taken for less than 1 month June 18, 2019

"Just started Savella about 2 weeks ago for my Fibromyalgia pain. It has relieved my pain some but not liking the side effects at all which have included dizziness, abdominal pain & discomfort & anxiety. Still trying to weigh out whether this script is worth taking or not. Going to finish up dosage & then make a decision from there."

Nettie · Taken for less than 1 month June 16, 2019

"This does help with the nerve pain, but I could not function even with the low dose. Gave me dizziness, felt high, no energy."

Pain · Taken for less than 1 month June 11, 2019

"This help with inflammation ,however I believe it's like chemotherapy the side effects is horrible ,nausea ,vomiting just feel ugh!!!"

Charly April 3, 2019

"Almost killed me- literally. I am still not ok weeks later. This medication should not be on the shelf prescribed in too large of dosages AND not be monitored daily - yup that scary and yup called the doc called the pharmacist- this is a very very serious lethal bad reaction drug"

i · Taken for 1 to 6 months April 2, 2019

"I take Tramadol for my Fibro and it helps with pain but needed something for severe fatigue and listlessness. I started Savella 25 mg twice daily and went up to 50mg twice a day . The sweating is unbelievable. I change PJ's twice a night because I'm soaked. The last two days now I'm experiencing severe shakes , palpations, sweating when ever I want to clean something . I have to get off of it because I'm afraid something will happen to me. I have no difference In the fatigue at all all. I'm making a appointment with a neurologist in the hopes he can help ."

UCTDJill · Taken for less than 1 month February 8, 2019

"Have undifferentiated connective tissue disease, lupus markers, could be fibro. Anyway muscles hurt. Savella the first week gave me the feeling of loosing all hope. The feeling of why am I here? what is my purpose? I stopped taking, didn’t get through the first pack. I called pharmacist and asked how long will it take for this med to leave my system. He said 3 days. For me Tramadol works the best. Teva brand out of all."

Luckyprincess · Taken for 6 months to 1 year January 17, 2019

"I really wanted to love Savella. It seems ok the first 4 to 6 months I was on it until I started getting heart palpitations and short of breath, my heart rate would go up to almost 200 with minor tasks. I didn’t realize how bad it was I until I had to go to the ER to get checked out. Be careful on this med, when it works it works great but I was only on 50mg a day and I’m pretty sure it messed up my heart for good. The reason it hasn’t been approved in a lot go places over in Europe is because the risks outweigh the benefits in most of their studies."

Oohma · Taken for less than 1 month December 12, 2018

"I was only on Savella 1 week when I developed a severe reaction to the medication. It started with migraine and within a day I had swelling of my throat and face. I had to make an emergency trip to the hospital."

mandyt November 17, 2018

"I have recently started taking Savella for Fibromyalgia. I started out with the small dosage for the few days and now I am up to 2 pills twice a day. I am honestly going to have to say, I haven't actually done that yet because I am having major insomina. Which I already suffer from and this is making it worse. I am making sure to take this early in the morning and with food so I don't get sick . I did notice within the first days I was a little irritable. Especially when on the phone, talking with others but I am fine now. I think I have been on this medication a little over a week now, I have felt a little ease in pain overall in body. It is hard to really know because I am also suffering from Ostoarthritis in my hands, bulging disk in low back,hip/groin pain and been having knotting issues within my shoulders. I also suffer from migraines as well and now a 5 yr breast cancer survivor. I have also purchased one of those therapy back canes to see if that helps relieve the knots."

Anonymous November 11, 2018

"It helped with pain, wasn't afraid to get out of bed in the morning because of the severe pain. Helped with tingling in hands and feet. Still have brain fog. I did not have any side effects. Great medicine!!!!"

Cj September 19, 2018

"I was put on Savella 3 yrs ago. I had some side effects titrating up to 100 mg, but once I got up to 100 mg they subsided. I did very well on it! But my insurance at the time was a problem. They tried me on Cymbalta, which caused Migraines - which I hadn't had since having my last child 24 yrs ago - and I was prone to migraines for over a year after going off of it. Now they've given me Lyrica, which is very close to Cymbalta - so I'm very hesitant to take it. I'm going to ask to go back on Savella and hope my insurance has changed enough to allow it. It gave me the most relief with the least side effects!!"

Alaskalady · Taken for 1 to 6 months September 17, 2018

"Lyrica made me drowsy and puffy. Cymbalta made me feel weird and killed my sex drive. Savella has been a blessing for me! I have more energy, less pain and feel like a lot of me brain fog has cleared up. I have Ehlers Danlos and possibly fibromyalgia which I use this for. I can feel pain when I hyperextend but the reticular nerve pain is almost gone. Maybe 2-3 days out of the month I have an odd day but not nearly as many as I used to, plus the SNRI seems to keep me cheerful. Have to take with food or I get nausea. Had BP spike, high pulse and sweats first month but they went away after. I pray this med continues to work! Get prescription drug card from website! Much cheaper, even with insurance."

Sim · Taken for less than 1 month August 31, 2018

"Need lots of water to drink, take with food, nausea will happen if I do not. My vision is a little more blurry, but my time to get new glasses is coming in a few months. Overall this medication is the first out of all the meds I have tried to help the most. I gave my doctor a hug because my pain went from tears to tolerable and able to go to work and do my job. I had to fight my insurance for this medication as it was not listed to cover but was approved after 2 weeks of going back and forth"

Claudia · Taken for 5 to 10 years June 30, 2018

"Savella was the first drug that really made a difference in my fibromyalgia. It has significantly reduced my overall pain without the sedating side effects of drugs like nortriptyline. Also, no weight gain. I had been taking so much OTC pain relievers I was worried about GI and liver damage. Also, I had been taking so many hot baths and showers that my skin was suffering. After going on Savella, I was able to cut back dramatically on my pain meds and the dermatologist is much happier with how my skin looks."

Rose · Taken for less than 1 month June 21, 2018

"I’m just starting on savella! I’m praying it will help with the fatigue and alertness. Pain also of course. I’ll let y’all know!..:)"

Anonymous · Taken for 6 months to 1 year April 24, 2018

"I have taken Savella for 6 months. I have some brain fog but it has decreased from what I originally had. I was suffering from severe muscle pain and it completely stopped. Another side effect I (did not suffer but loved) was the 20 lbs I have lost over the period. The cost is so much that I cut the dosage from 50 mg. 2 X a day to 25 mg. once a day but still get the pain relief just as much. My thanks to the mfg co!"

Crystal · Taken for 1 to 6 months March 19, 2018

"My Dr. put me on savella after my lyrica and cymbalta stopped working for my fibromyalgia pain. I wish I had read these reviews before I wasted $200 on these terrible pills! My pain has been worse since starting it. I’m nauseous all the time, get cold chills, go to the bathroom 2 times every hour, I can’t get to or stay asleep even with sleep meds and I itch all over. I have had a horrible experience with this drug and wouldn’t recommend it at all!"

SunKimmy · Taken for less than 1 month February 23, 2018

"I started Savella for fibromyalgia. I only took it for four days before ending up in emergency room. It increased blood pressure which is normally around 101/62 and now shot up to 138/98 in 4 days!!!! I ended up in the hospital with palpitations and heart squeezing with chest pain so bad I thought I was having a heart attack. This drug feels like poison to me. I just got released from the hospital and waiting for the Savella to leave my body. It's a shame because I did feel pain relief. I have one kidney and was hoping this would be my saving grace. I don't know where to go from here. I am already on Gabapentin."

Ddebru01 · Taken for 5 to 10 years December 6, 2017

"My pain management physician had tried multiple medications to treat my severe Fibromyalgia prior to Savella. They decided to try Savella to replace the Cymbalta. While neither medication worked very well on It's own, the combination of the two worked well for me. The Savella alone helped with the pain, it made my mind foggy. When both were combined, I had some pain relief and better mental function. I still suffer with fibro fog and cognitive difficulties but it's better than without both medications."

Cherub528 November 21, 2017

"I took this medicine only once had a violent reaction dizziness, vomitting, I felt like I was poisoned. Will never try again if I could give less than one I would."

Made me sick · Taken for less than 1 month October 17, 2017

"First let me rate it a 1. I was supposed to take 25mg at bedtime. Woke up a little before 2 am, heart racing, hot flashes, extreme nausea. Spent next hour trying to sleep but heart palpitations, hot flashes then chills, vomiting and needing the bathroom.... 4 times! I have NEVER had this type of drug reaction like that!!! Unreal! Charging my insurance nearly $1,000 for a rubbish drug that makes people sick. Even people who don't have a severe reactions all have nausea! It shouldn't be legal to charge people so much for a drug. It is price gauging and insane! I still feel sick next day. Never again. Now I am stuck with pills worth more money than I can make and hate them."

Cherylann654 October 7, 2017

"I've had fibromyalgia now since I was in my 30's, I am now 63. Back then, I was told It was depression, all in my head, you name it. I tried several Medications, nothing helped, until I tried Savella. It's a miracle medication for me, although I take the highest dose allowed, 100mg 2x a day. The only problem, it's very expensive. My prescription plan pays some, but I'm stuck with a bill of about $1200 a year. Unfortunately, I can not get help because I inherited my Moms IRA that has $35,000 in it...Sad they can't make this a generic drug ☹️. I feel trapped because I feel like I need thus medication to survive."

Steph Anne · Taken for 2 to 5 years September 20, 2017

"I have had fibromyalgia for about 10 years now. My Dr tried Cymbalta and then Gabapentin which both seemed to help at first, but only for a short time. Then maybe 4 years ago, a new Dr. put me on savella. At first I felt nauseous, dizzy, and had headaches every day. All those symptoms continued, but not as severe, but I started feeling like I could get around better, & my muscles weren't as stiff or sore as before. But then being diagnosed with BPD and anxiety, those meds weren't where they should be, and I started feeling really down and depressed. I told my Dr 's about it. Then trying to get the savella refilled, I found out they weren't going to refill it because insurance said I had suicidal ideations. BUT after 4 weeks w/o it, I feel so much better! No sweats, dizziness,etc"

Jillyn31 · Taken for less than 1 month September 8, 2017

"I wasn't even able to get through the titration pack & I began experiencing suicidal thought. I've experienced it a lot, but this time it was way worse, with the thoughts getting more frequent & graphic. I will admit I have BP & BPD & this may be the reason why I had this reaction. I called my rheumatologist, since she's the one who prescribed it, to let her know how I was feeling. Long story short, she sent the police to my house & I was taken to the psych hospital, where I sat for a couple of hrs. It also made my already high blood pressure worse. Also, no pain ease/relief. Never again for me!"


Learn more about Fibromyalgia

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Symptoms and treatments

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