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Desoxyn for ADHD User Reviews (Page 2)

Reviews for Desoxyn

Commonly mentioned side effects
  • lum...
  • Taken for 1 to 6 months
  • June 18, 2012

"MUCH BETTER than Adderall, Vyvanse, or Dexedrine, or Ritalin. IT is more effective for performing my scores on tests and learning. It is better for the social anxiety component of ADHD. It is neurotoxic, so you may not want to stay on it for the entire year, however, IT DOES have medical value at low doses if used by RESPONSIBLE users for several months out of the year. IT IS very effective for controlling treatment-resistant depression and appetite problems as well. However, appetite would return to baseline when stopping Desoxyn. I think this medicine should be strictly controlled, but should be available to patients who could truly benefit from it. It has helped me get through a very difficult year, but my doctor took me off it."

10 / 10
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  • als...
  • Taken for 6 months to 1 year
  • November 21, 2022

"I've spent six years trying every other ADHD med I reasonably could, some of them multiple times, and can't tolerate any of their side effects. Vyvanse stops my will to do anything and gives me constant dread, Metadate made me super irritable, and Adderall kicked in so fast I got horrible jitters and wore off so fast I felt brain dead. It all made me feel broken and hopeless. All I've ever wanted is something I can take like an antidepressant, that I don't feel, that doesn't remind me how dysfunctional my brain is without it. Desoxyn is that med. I don't feel it kick in, and it lasts almost all day and wears off naturally as I wind down. It just does what it's supposed to do, and I haven't had to increase my dose (5 mg) in the year I've been taking it. It actually makes me pay attention, not just hyperfocus. I'm more present in conversations and my day-to-day life, more confident and outgoing. So glad my psych was willing to prescribe it."

10 / 10
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  • Mur...
  • Taken for 2 to 5 years
  • January 8, 2025

"This medication has saved my life. I think of how my mental health was before I was prescribed this medication for my ADHD/Autism/BPD/Anxiety diagnoses, and it's like comparing apples to potatoes. I began traditional psych/therapy at a young age, so experienced the psychiatry guinea pig game for years. Thus, I have been prescribed almost every 'acceptable' medication regimen under the sun (other stimulants, anti-psychotics, mood stabilizers, anti-depressants, etc.) and experienced hospital/treatment stays due to my diagnoses, as well. Life always felt like a shade of grey. Fortunately, my current doctor is a believer in alternative therapies/medicines, so recommended trying Desoxyn as a last resort. Unlike traditional psychs, my doctor never set expectations of being 'cured', was honest, and never attempted to instill fear. I find it to be truly shameful how they treat and speak of this medicine and those who take it. It has been a wonderful treatment for my mood, function, and overall well-being."

10 / 10
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Frequently asked questions

  • Anonymous
  • June 22, 2008

"I would give it a 10 but will err towards conservative and give a 9; only because it has a high abuse potential and humans are inherently prone to some type of addiction. It has pretty much NO side effects if taken as directed for adult ADHD, and after 5 years on it, I feel it has stabilized me more than any others. Adderall is second place for me, but it is more likely to make me irritable after therapeutic effects wane for the day. I have taken Desoxyn before and fell asleep!"

9 / 10
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  • Fat...
  • November 17, 2009

"Desoxyn has opened doors to my life, heart, and mind that I thought would never be able to be opened and be shared with the world. The side effects were little to none and other medicines' side effects greatly outweighed the Desoxyn effects."

10 / 10
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  • Bos...
  • November 5, 2016

"I've used all the first-line ADHD meds beginning in 2003, and only one was effective, but of course my tolerance is depleted; it's not so effective now: Adderall generic 30XRAM, 0 regular PM. Yet, without it, I'm like a hyperactive confused kid again. I don't want a higher dosage. I want a change; I asked my older psychiatrist (been with him since the late 1980s) about Desoxyn, which he said, 'I've never heard of it.' He's 100% psychopharmacology. He treats kids through seniors; MA-trained MD, Harvard + BU Med School. Is it possible that MA laws never permitted this medication to be used for ADHD? Should I ask again, or won't I find it in MA pharmacies? I don't want to sound like a druggie either, but it's frustrating to be stymied. At my age, 62.5, I'd like some relief again."

5 / 10
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  • Ale...
  • Taken for 10 years or more
  • June 21, 2023

"Like all the other reviewers, I have tried all the other 'modern' ADD stimulants. The common theme of all other reviewers is that these medications all leave the user feeling 'jittery' or 'tweaked.' This is my experience as well. I can only describe the stimulative effect as so very much 'cleaner.' It is an entirely superior experience in every manner. There are only two disadvantages. 1. Its base chemical name is methamphetamine; as soon as you bring this up to your prescriber, they will immediately suspect you are a meth head trying to get high legally and will be highly suspicious of you and resistant to prescribe it for you. Due to the drug schedule levels, it must be specially ordered for you. Additionally, it is unavailable in higher strength tablets, only in very small 5 mg. Effective therapeutic levels call for a dosage of 30 - 60 mg twice daily. I guarantee your doctor is going to be very resistant to prescribing you 6-12 pills 2x daily."

10 / 10
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  • Che...
  • Taken for 2 to 5 years
  • February 4, 2022

"Desoxyn was the greatest treatment for my ADHD I have ever received. Alas, I lost access to my prescribing doc and thus his scripts several years back over a national shakeup in health insurance. Naturally, some should never be prescribed this drug (it's methamphetamine after all). Abusers aside, however, if one struggles significantly with ADHD, Desoxyn may be the key when all else falls short. It certainly was for me. At the time of my Rx, I was completing graduate courses, all of which I aced. I also received flawless scores on two different research papers. I was dosed at the advised max of 25mg/day; and while I could sense the stimulant working, I wasn't beset by dependence, and it never triggered euphoria or enticed me to abuse it in any way. Given the stigma that surrounds Desoxyn, and with insurance getting ever more selective over drug coverage, I regret not expecting to reap Desoxyn's benefits again. But I'm thankful for the remarkable blessing it was while it lasted."

10 / 10
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  • Bob...
  • Taken for 2 to 5 years
  • November 9, 2023

"I've got several gene variants that make the usual stimulants (regular amphetamines like Adderall or Vyvanse, methylphenidate like Ritalin or Concerta) not work very well. With the usual stimulants, I need to take large doses (combination of extended and instant release throughout the day), they wear off quickly, and work fairly poorly and inconsistently. Regular amphetamines completely stop working after a week, even at large doses. Desoxyn (methamphetamine) works extremely well, works all day (7.5mg instant release dose 2x daily), works consistently without having to take breaks, and helps where the usual stimulants fail. Most notably, it helps very well increasing my working memory to normal levels (or at least what I imagine that would be). Despite the stigma surrounding methamphetamine, it feels way less stimulating than even methylphenidate does. Unfortunately, it has been unavailable for the past year, with no return apparently on the horizon... :("

10 / 10
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  • Hop...
  • Taken for 1 to 6 months
  • December 10, 2021

"24-year-old male here. Wish I could explain my full 6-year story and share advice and words of support, but there’s a char limit. My experience: 1. Adderall didn’t work, caused anxiety at higher doses (IR & XR). 2. Concerta 36 mg helped a little. 54 mg genuinely worked… for the first 2 days. 3. Focalin lived up to its claims. More tolerable & effective. I still couldn’t work like a normal person. 4. “Final showdown” time. Requested a month of Desoxyn, then a month of Dexedrine. 5. Lots of experimenting (within FDA guidelines). I found them to be the 2 most effective, with Desoxyn winning. (Um… no idea why 3:1 AMP salts combo did nothing.) It’s neither magical nor scary. I’d say #1 for efficacy, #2 for tolerability (2nd to Focalin). Feels similar overall to other ADHD meds. Only anomaly was mild euphoria the first 2 days. Less addictive than coffee. Only “big W” could order it. Even on this, I still struggle. But it’s the best I’ve got."

8 / 10
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  • Pub...
  • Taken for 1 to 6 months
  • April 7, 2023

"Prescribed Desoxyn for ADHD, initially 5 mg/day up to 20 mg/day. It helped a bit with focus and motivation, but it caused profound discomfort, e.g., increased anxiety, a rapid heart rate that was distressing, dry mouth. I don't know why people rave about Desoxyn. I think it's because it's methamphetamine, so they think it has to be good. Since it's the most potent stimulant, it has to be the most effective. That logic is flawed. Desoxyn has a very narrow therapeutic index. It can cause neurotoxicity at slightly higher than usual doses, and the long-term effects on the brain are unknown. I would stick to the amphetamine salts, such as Adderall. It never made me feel edgy and uneasy, in fact, it was 'gentle' and just worked. It didn't cost an arm and a leg. Desoxyn only comes in 5 mg tablets. The usual dose is 20 mg-25 mg a day. It ended up costing me about $670/month. Insurance rarely pays for it. Maybe there's a tiny group for which Desoxyn is appropriate. But I have a lasting aversion to it."

3 / 10
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  • Rx2...
  • October 27, 2009

"I took the tablets after being on all forms of Dexedrine, Ritalin, Adderall, etc. It had no side effects, but was not as big a deal as it is made out to be. Dextroamphetamine spansules (brand SKF) are far more effective and long-lasting for ADHD, which I've dealt with."

7 / 10
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  • Yuk...
  • Taken for 1 to 6 months
  • January 2, 2022

"I don't get all the hype for this drug. I took Desoxyn for a few weeks but never really noticed much of an effect, other than maybe a little help for focusing on personal projects. I am diagnosed with inattentive ADHD, but maybe this drug works better for people with the combined or hyperactive types. It made my stomach feel weird, but didn't have any other major side effects. Definitely not worth the ridiculous price tag. Hard pass."

2 / 10
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  • mar...
  • November 17, 2015

"10/10 miracle for my ADD, fog/fatigue, OCD. Can now take things one at a time. No more racing thoughts! Minimal side effects. Thank you for helping!"

10 / 10
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  • Tri...
  • March 10, 2008

"The Cadillac of ADD medications! Little to no side effects. Only one that truly helped me."

10 / 10
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  • Anonymous
  • December 6, 2011

"Works very good as a stimulant in the treatment. It also helps in calming the brain. Storm of thoughts without the hyper focus that other stimulants seem to bring on."

7 / 10
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  • Nob...
  • July 26, 2022

"This is the only stimulant that works. No increased heart rate, no increased blood pressure, no anxiety. It just works. It actually helps me sleep."

9 / 10
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20 Report
  • Des...
  • March 3, 2024

"Desoxyn could be a lifesaver. I like this medicine very much. It is very good to use it carefully and under a doctor's supervision. I am glad I know this medicine."

10 / 10
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Reviews may be edited to correct grammar/spelling or remove inappropriate content. Reviews appearing to come from parties with a vested interest are not published. This information is not intended to endorse any medication and should not replace the expertise and judgment of healthcare professionals.