Maprotiline User Reviews & Ratings

• elk...
• January 7, 2011

Maprotiline for Panic Disorder "I have been on maprotiline for over 20 years to treat my panic disorder. It was the only medication that worked and I tried just about all of them (tricyclic antidepressants, MAO inhibitors, Prozac, Wellbutrin). Hands down, this medication had the least side effects and the best coverage. I have been living a full life, panic free."

• Dot...
• February 3, 2014

Maprotiline for Depression "I had been on Ludiomil for over 30 years, and they discontinued it. I went on the generic maprotiline, and now they're going to stop it too. I'm beside myself. I have about another month, and I will be out. This medicine saved my life. I can't believe they could just stop making it for those of us on it. They say it is not addictive, but let me tell you I have tried several times to get off of it, and I get all the same symptoms I had over 30 years ago on top of the withdrawal symptoms I'm going to get. Life is about to go bad again. The doctor and I talked, he says he won't mix maprotiline with any other medicine, and I'll have to be off it for 2 weeks before starting another medicine. This will put me into a severe depression. Nothing else works."

• Ran...
• Taken for 10 years or more
• November 11, 2019

For Major Depressive Disorder "I’m 45 years old and have been on this Rx - Ludiomil, then its generic maprotiline since age 9. It just recently became unavailable in the U.S., and the fears I’m having about no longer being able to be stable were debilitating until learning I can get Ludiomil from an online pharmacy in Canada. This Rx is a lifeline for me. Anyone concerned about going off it needs to contact them. I’m going to stockpile as much as I can in case it becomes no longer available via Canada, so I’ll have enough to safely transition to another drug."

• Wai...
• Taken for 10 years or more
• October 21, 2020

For Major Depressive Disorder "Maprotiline is the only antidepressant that is rated a 10 for major depression, yet it has been taken off the market. Has anyone found anything comparable to it? I haven't. Are you able to get it in Canada now?"

• Fru...
• Taken for 10 years or more
• June 15, 2020

For Depression "Still calling the manufacturer to see when maprotiline will become available again! Was told May, then June, and now August. Not sure why it is so difficult to make. Trying my fifth antidepressant, and nothing works as well with the least side effects as maprotiline."

• Sou...
• Taken for 10 years or more
• May 19, 2015

For Depression "I have been taking maprotiline for over 35 years, and I am still taking it (there seemed to be a shortage for a while about 2 years ago, but Walgreens still carries it). I started having panic attacks with the onset of my allergy to dust mites when I was a teenager. In my 20s, I went into a deep depression and couldn't sleep for 3 months. I started taking maprotiline, and 3 improvements occurred: 1) My depression subsided and then went away. 2) My panic attacks stopped. 3) The almost daily sneezing episodes associated with my allergy subsided, and now they occur maybe twice a month. My runny sinuses also dried up considerably. I twice tried taking myself off of the medication--it didn't work. All problems returned after about 10 days."

• Anonymous
• Taken for 10 years or more
• July 23, 2019

For Depression "Maprotiline has been extremely effective for me for over 35 years. I have had difficulty getting it for the last 12 months and now just learned the name brand Ludiomil is still available through Canadian pharmacies."

• sue...
• August 31, 2020

For Depression "I've been taking maprotiline for 26 years. Everything was going great until Mylan stopped making it. My body was so used to it, I cannot stop taking it. I keep calling Mylan and have been getting the runaround. I've started getting it overseas, Turkey is where it's made. It hasn't worked as well. This has really been hard on me. I hope Mylan gets a heart and starts making it again."

• bal...
• Taken for 1 to 6 months
• February 10, 2017

Maprotiline for Depression "I tried Ludiomil over thirty years ago when I was severely depressed. Of all the different antidepressants that had been prescribed for me (amitriptyline, doxepin, nortriptyline, desipramine, trazodone, etc.), Ludiomil was definitely the most effective of the ones I tried. Unfortunately, it, like Remeron (which I tried years later), raised my liver enzymes, and I was told by my physician (I was seeing a psychiatrist at the time) to discontinue using it. But I was lucky: just before I was scheduled to undergo electroshock therapy to cure my intractable depression, I learned that I was allergic to the milk protein, and after removing it from my diet, I never again had the deep melancholy I had experienced before."

• Bob...
• Taken for 10 years or more
• January 24, 2020

For Depression "I have been using maprotiline for many years. I’ve tried every antidepressant, and it is the only one that works. I too am having trouble getting it, and I’m very concerned. I’ve seen that some people are getting this from Canadian pharmacies. Can anyone share the names of any such pharmacies? Help!"

• Poo...
• December 6, 2019

For Depression "I have been taking this drug, maprotiline, for depression for 30 years, and I feel very safe taking it and have no real side effects. The problem is it is backordered, and I had a hard time finding any of it except from Canada. The manufacturer says it will come back in February or May. I am not sure that will happen. My question: Did anyone transfer to a different drug, and what was its name, and how are they feeling? I am very upset that they will not continue to make maprotiline."

• has...
• Taken for 1 to 6 months
• January 21, 2015

For Panic Disorder "Effective medication for panic disorder and for highly somatization patients, also very helpful for insomnia. I suggested maprotiline for a patient with no response to SSRIs or tricyclic antidepressants."

• Roc...
• Taken for 10 years or more
• December 20, 2022

For Depression "I started using Ludiomil in 1984 for depression and anxiety. It took a while to start working, but it did its job well. I used it until the manufacturer discontinued it. I have tried three other antidepressants, and the side effects were so bad that I completely discontinued them. I only use diazepam for anxiety. I feel like crap ever since I stopped Ludiomil three years ago."

• myl...
• November 11, 2024

"I too took Ludiomil for 30 some years and was also concerned when Mylan said they were working on something. It seems that the company never informed the customer support team what was going on, nor would Mylan make any effort to explain. At one point, the word 'ingredient' came up, and that is what I believe was the problem. The pharmacy in Canada that I used was CanadianPharmacyKing. They were very easy to work with, but I found the product was not as good, which reinforced my belief that it was an ingredient issue. I see that Japan is also selling the product now. Be aware that this med vs. the original one might affect your memory. I was taking it for about 6 months and decided the memory problem may not be worth it, thinking I might find an alternative, BUT haven't yet."

• Poo...
• Taken for 10 years or more
• May 12, 2020

For Depression "Just wondering if anyone has found a place that has maprotiline. I was getting it from Canada, but it came from Turkey, and now it cannot be mailed from there because of the virus."

• Map...
• February 27, 2009

For Depression "I've been using maprotiline for ten years. I think it's the best antidepressant out there, but since it's not new, it's not being prescribed."

• Nac...
• Taken for 6 months to 1 year
• July 13, 2015

Maprotiline for Major Depressive Disorder "I was pleased with the results of this medication. Eventually, I was able to discontinue taking this medicine after 8 months."

• bec...
• January 31, 2020

For Major Depressive Disorder "Filed complaint with Mylan Laboratories for discontinuation of Ludiomil (maprotiline). I was on it for 30 years, and now am in severe withdrawals. Can't find it anywhere. Looking in Canada."

• Has...
• Taken for 1 to 6 months
• January 13, 2016

For Panic Disorder "Helps me to sleep better, but no good for panic attacks, and only side effect: hypotension."