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Saxenda and Vomiting: What Users Say

Vomiting: mentioned by 112 users (7.7%)

Based on user experiences from 1,451 Saxenda reviews, the following table shows the most commonly mentioned side effects.

All user comments are moderated by Drugs.com. Each review is verified for relevance and screened for inappropriate content. Side effects are user-reported and not clinically verified.

nausea 38.2%
constipation 12.8%
headaches 10.8%
tiredness 8.1%
vomiting 7.7%
diarrhea 7.5%
fatigue 6.7%
heartburn 4.3%
loss of appetite 4.1%
sick 4.1%

Reviews for Saxenda

Commonly mentioned side effects
  • Cou...
  • Taken for 1 to 6 months
  • May 29, 2023

For Weight Loss (Obesity/Overweight) "An absolute miracle drug, lost 6 kg in the first month without even trying vs. most diets which were doing nothing. Get occasional slight nausea, but it's nothing to worry about. I've stopped increasing my dose as 1.8 mg seems to be working for now. A small word of warning that if you're planning a big night out, best skip the dose for the day, otherwise you WILL vomit (either on the night or the morning after, which, although it will save you calories, is not ideal). Gets a 10/10 for sheer effectiveness though."

10 / 10
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7 Report
  • Lyn...
  • Taken for 1 to 6 months
  • April 20, 2023

For Weight Loss (Obesity/Overweight) "Discontinued after taking for 4 weeks, the side effects are unbearable. Nauseated almost daily, multiple episodes of vomiting, and horrible diarrhea. I have lost approximately 10 pounds, however, the side effects are definitely not worth taking."

2 / 10
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4 Report
  • Gen...
  • Taken for 1 to 6 months
  • October 15, 2022

For Weight Loss (Obesity/Overweight) "My experience with Saxenda was mixed. There were some good things and some not so good things. My first attempt with Saxenda lasted about three weeks. My water intake increased and my sweet tooth disappeared, most food was unappealing. My appetite disappeared completely. I experienced lots of heartburn and nausea. Three weeks in, that became hyperemesis, I vomited multiple times after every meal. I woke up in the night and vomited. I passed out while at my local dog park. The good things: I lost 22 pounds. I became more physically active, and my impulse eating has decreased. I'd recommend Saxenda to others. I would recommend that prescribers offer more support and contact to people taking Saxenda."

5 / 10
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Frequently asked questions

  • Cur...
  • Taken for less than 1 month
  • September 7, 2022

For Weight Loss (Obesity/Overweight) "It is the worst drug I have ever taken! I was prescribed Saxenda by a GP to help with weight loss. By Day 5, I had violent vomiting for 8 hours, followed by diarrhoea. I ended up with broken capillaries on my face from the vomiting. I continued on but opted to stay on the lower dose. 2 days later, I had diarrhoea again. Bright yellow and pouring out of me. 4+ times an hour for 48 hours. I would not recommend this to anyone."

1 / 10
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11 Report
  • Ole...
  • Taken for less than 1 month
  • May 10, 2022

For Weight Loss (Obesity/Overweight) "I am just shy of a month and just upped today to 2.4 dosage. In the beginning, 6 days or so, I had bad nausea, some vomiting, and constipation. I almost stopped but just stayed in the .6 for an extra week, and I have been a bit more tired, but the other side effects have gone away. It has drastically curbed my appetite, and I just weighed myself and I am down 12.4 pounds and feeling very good. I am making better food choices as I get full after eating about 1/3 of what I used to, which was big portions and seconds. I have also bumped up my activity and averaging 13,000 plus steps and 100 plus active zone minutes on my Fitbit. I am happy so far and glad I didn’t pull the plug in the first week."

9 / 10
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9 Report

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  • MLR...
  • Taken for 6 months to 1 year
  • November 29, 2021

For Weight Loss (Obesity/Overweight) "I started taking Saxenda in January 2020 for weight loss. I gained 30 pounds when I went through menopause. I have a BMI of 34; had all the side effects: nausea, vomiting, severe acid reflux. Started slowly, and every time I advanced my dose, the symptoms worsened and then subsided. I was on Saxenda and never lost any weight. I had no appetite, as I could not eat without getting sick. I tried taking it in the morning and then at night before bed, thinking a different time of day would help. I achieved no weight loss and lost sleep from the acid reflux."

1 / 10
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  • Gil...
  • Taken for less than 1 month
  • October 1, 2021

For Weight Loss (Obesity/Overweight) "Started Saxenda a few weeks ago, and I have literally felt like nothing to eat since I started the pen. All my favorite things just don't interest me at all, and I couldn't even face the smallest bite. Really weird. Horrible vomiting the other night and constantly nauseated with heartburn too. Popping pills like Smarties. Hope this passes in a day or two. Can't continue like this much longer."

8 / 10
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2 Report

More FAQ

  • Pet...
  • Taken for 1 to 6 months
  • September 20, 2021

For Weight Loss (Obesity/Overweight) "I've read through the other reviews and feel sorry for the people experiencing severe side effects. Makes me wonder if it's a result of using the maximum 3 mg dose from the start? I will say that my experience wasn't free of side effects. Started off on 0.6 mg per day. Just sipping water or thinking about food caused me to vomit violently. I mean, I wouldn't be surprised if my boots flew out of my mouth. The first two days were a struggle just to stay hydrated. Day three, I started to feel okay. I had to struggle to eat a bowl of soup. By day seven, I could eat a bowl of soup and some toast. Due to the side effects, I stayed on 0.6 for a fortnight before moving up to 1.2 mg. Now I'm on the full 3.0 mg dose with no side effects at all. I am satisfied with a bowl of cereal for breakfast, one sandwich for lunch, and 170 g of steak and a small amount of veggies for dinner would be a feast. Losing 2 kg/5 lbs per week. At week 10, lost 25 kg/55 lbs."

10 / 10
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41 Report
  • Mmm...
  • Taken for less than 1 month
  • September 2, 2021

For Weight Loss (Obesity/Overweight) "I am now in my third week of Saxenda and have not lost a single pound. I have constant nausea, and if I drink coffee, I vomit almost immediately. Have some stomach and back pain, but unfortunately no weight loss, very disappointed."

2 / 10
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2 Report
  • Rox...
  • Taken for 1 to 6 months
  • August 14, 2021

For Weight Loss (Obesity/Overweight) "I started Saxenda on the 4th of June. I had a BMI of 32 (obese) and my starting weight was 87.5 kgs. Now, 10 weeks later, I am now weighing 76.6 kgs, so lost 10.9 kgs so far, which I am very happy with! And a BMI of 28. The first few weeks took some getting used to, with a lot of burping, and I was sick on the 2nd day (vomited). I do my injection before bedtime, and sometimes still wake up feeling a little nauseous, which a small breakfast helps. My cravings have been massively reduced, and I can never finish my plate, and yet feel full. Overall, very satisfied so far, and will carry on treatment for the next few months. I wasn’t looking to lose too much weight, and I’m not far off my target."

10 / 10
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  • Sun...
  • Taken for less than 1 month
  • August 13, 2021

For Weight Loss (Obesity/Overweight) "Please, if you suffer from migraines, do not take this medication. I only used one dose of an injection, and I’ve been violently ill for the last 24 hours with a severe migraine and throwing up constantly. I know the side effects are different for everyone, but I wish I had listened to the people on here with migraines who said don’t do it. It’s taught me a very big lesson that if you need to put a pill in your mouth or inject yourself to lose weight, don’t bother. I’m going to go back to doing it the hard way, but without feeling absolutely wretched."

1 / 10
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6 Report
  • ECa...
  • Taken for less than 1 month
  • July 19, 2021

For Weight Loss (Obesity/Overweight) "I have used Saxenda for 3 days - I started with 0.6 mg as directed. I am experiencing abdominal discomfort, nausea, and vomiting and will not be continuing this medication. Weight loss is very important to me, but not worth being miserable."

1 / 10
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6 Report
  • Lin...
  • Taken for less than 1 month
  • July 16, 2021

For Weight Loss (Obesity/Overweight) "I lasted 24 hours on this stuff. The following morning after my 1st injection, I had vomiting, diarrhea, abdominal pain and bloating, headache. I haven't been this sick in years... awful experience."

1 / 10
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6 Report
  • Ban...
  • July 12, 2021

For Weight Loss (Obesity/Overweight) "Have been taking Saxenda for about a month but haven’t been able to up my dose to 3.0 since I’ve been having horrible severe headaches and nausea, watery diarrhea, and vomiting nonstop for weeks. I have no energy. I’m miserable. I wonder, will this be worth it? :( I’ve lost about 4 kg, that’s all, and I can barely eat or do anything from how sick and weak I am. Was very excited to try the medication, but I’m so upset. Any recommendations? :("

4 / 10
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18 Report
  • Pat...
  • June 5, 2021

For Weight Loss (Obesity/Overweight) "I have been on Saxenda for 1 week now and just increased my dose to 1.2 today. From the first day I experienced a suppressed appetite, which was great. When I started last week, I was 120 kg, and today I weighed in at 118 kg. I am happy that it is heading in the right direction. At day 5 of injections, I became very ill with reflux, vomiting, headache, burping, no energy, bloating, and abdominal pain... a horrible feeling. Because of this, I have not exercised at all. Today on day 8, I feel a little better, but the bloating still remains and is uncomfortable. I will stick with it because I do have high hopes for this medication. In Australia, I’m paying around $380 plus needles (100 for $19). It is suppressing my hunger and cravings, my body wants fruit and veg, anything else feels wrong and does not satisfy. Stay hydrated. I'm off to the chemist to hopefully find some relief for my bloated tummy... it’s like I’m 7 months pregnant!! Hope to follow up with some good news next week!!"

8 / 10
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79 Report
  • Ema...
  • Taken for less than 1 month
  • May 28, 2021

For Weight Loss (Obesity/Overweight) "This was a really bad experience. Took Saxenda for 3 days, only a dose of 0.6, and ended up with side effects of severe nausea, vomiting, watery diarrhea, stomach ache, headache. Could not even drink water due to severe nausea, got dehydrated. Stopped the drug, and the side effects lasted for 5 more days! Would never recommend this drug to anyone."

1 / 10
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7 Report
  • Smi...
  • Taken for 1 to 6 months
  • May 10, 2021

For Weight Loss (Obesity/Overweight) "I’ve been on Saxenda for a month now and lost 12 pounds. I’ve increased my movement and lowered my calorie intake. I’m at 1.8 mg and have started feeling most of the common symptoms: nauseous, diarrhea, and vomiting. I’m hoping my body will adjust soon."

7 / 10
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18 Report
  • Stu...
  • Taken for less than 1 month
  • May 8, 2021

For Weight Loss (Obesity/Overweight) "Tried Saxenda after years of trying other things and failing. COVID lockdown in March 2020 led to 45 lbs weight gain by March 2021. In April 2021, I started on Saxenda at 0.6 mg for 10 days. Lost 3 lbs; like the others above, constant craving and binge eating went away like magic! Including coffee aversion. Upped the dose to 1.2 mg; by day 5, I had severe GI issues - woke up in the middle of the night to vomit, constant diarrhea, burps that smell and taste like rotten eggs. Sat in bed sick and did not eat for 4 days. Because I have kids and a full-time job, these side effects are a deal breaker for me. Either they had to go, or Saxenda had to go. Talked to my doc and dropped the dose back to 0.6 mg, which I will stay on for 2 more weeks before trying the 1.2 mg dose again. I never got to the peak dose of 1.8 mg and am not sure my body can tolerate. After 25 days, I lost 10 lbs, but it may be because I ate almost nothing for 10 days of feeling sick. I am not sure if the lower dose will work, but I will try."

7 / 10
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  • Vom...
  • April 4, 2021

For Weight Loss (Obesity/Overweight) "This drug Saxenda makes you sick to your stomach and vomit everything you eat. If you do eat, you feel nausea constantly! No appetite, no energy. I would advise anyone who is thinking of taking this to help lose weight, don't take this drug."

2 / 10
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9 Report
  • Exo...
  • March 11, 2021

For Weight Loss (Obesity/Overweight) "Works great, I lost 8.4 lbs in the 1st week, but at a cost. Never so sick in my life! Threw up everything but my spleen! Started out with the belching. Sounded like an old drunk. Then the bloat began. My stomach looked and felt like I swallowed a hot air balloon. Next, the diarrhea, nothing but pure liquid. At this point, I was a little concerned about becoming dehydrated. Finally, the vomiting, the violent, whatever you ate was coming out of your nose kind of vomiting. I was like, 'There is no way a medicine could make a person feel this bad!' But it can, and did! However, I still feel this could be a good weight loss solution, especially since I have high BP, and this doesn't have stimulants and is 'safer.' Reading over other reviews, some people are having great luck with it. My doctor called me in Zofran, and I'm only going to do 0.3 every other day to see if my body adjusts. If I don't see an improvement in 2 weeks, I will just accept this is not a medication for me and go another route."

6 / 10
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46 Report
  • Cyr...
  • March 5, 2021

For Weight Loss (Obesity/Overweight) "I have been on Saxenda a little over 1 month. Thus far, I have lost a total of 11 lbs (which is amazing as on my own, I was gaining 1-2 lbs every week prior to starting this medication). My main side effects for the 1st few weeks were consistent nausea, increased reflux, and severe constipation. I got all the way up to the 1.8 mg dose and realized quickly that I could not handle this dose and went back down to the 1.2 mg dose. On the 1.8 mg dose, I had extreme upper back pain related to increased reflux, nausea, projectile vomiting, and abdominal cramping. After 2 weeks of being on the 1.2 mg dose, most of these side effects have gone away. My bowel movements have returned to normal, albeit on a slower schedule due to delayed gastric emptying. On this current dose, I don't notice much of an appetite change, but I do not eat much as it is. If you are considering this medication and have the resources to obtain it, 100% go for it."

8 / 10
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1 Report
  • Chr...
  • Taken for less than 1 month
  • February 18, 2021

For Weight Loss (Obesity/Overweight) "2 days in on 0.6 mg and the nausea, vomiting, stomach pains, diarrhea, sulfuric burps have hit me hard. My stomach was so painful last night that I’ve decided to discontinue. It feels like it is bad for my body. You may be someone who doesn’t suffer from the severe side effects, but I did, and it was horrendous. An expensive mistake."

2 / 10
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7 Report
  • Chu...
  • Taken for 1 to 6 months
  • February 18, 2021

For Weight Loss (Obesity/Overweight) "Started Saxenda 4 weeks ago and now on 3 mg. Have no appetite, 3 weeks of nausea and vomiting. I still get nauseated at times. Started at 335 lb, am now 305 lb. I'm concerned about the stones, cancer, and other serious side effects. Without this, I couldn't lose weight, I was just hungry non-stop. I still crave sugar, but not much. I eat between 200 and 800 calories most days, from a vegetarian diet. I get horrendous sulfur burps that are likely caused by having an empty stomach too long. Shakes are your friend. My goal weight is 170, so I've got a ways to go."

7 / 10
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15 Report
  • Tir...
  • Taken for less than 1 month
  • February 13, 2021

For Weight Loss (Obesity/Overweight) "I started Saxenda 1/17/21. I am up to the 2.4 dose and have lost 18 lbs. The side effects have been rough. Nausea and vomiting occur weekly and get worse after I increase the dose. I am hopeful that my body will get accustomed to the med and the side effects will lessen. I find that I don’t eat a lot because I feel sick most of the time. I was thin half my life and obese the other half, and have gotten to the point I don’t want to go out because of my weight. If the weight loss continues, it will be worth the constant sickness. I just take one day at a time and set my mind to my goal - to feel better about myself."

9 / 10
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364 Report
  • Fea...
  • Taken for less than 1 month
  • January 14, 2021

For Weight Loss (Obesity/Overweight) "After day 1, I had the worst vomiting and nausea of my life. Had to stop taking this poison."

1 / 10
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20 Report

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