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Lamotrigine and Tiredness: What Users Say (Page 3)

Brand names: Lamictal, Lamictal XR, Subvenite, Lamictal ODT, Lamictal CD

Reviews for Lamotrigine

Commonly mentioned side effects
  • Lau...
  • Taken for less than 1 month
  • February 3, 2021

For Bipolar Disorder "It is making me feel like a zombie and completely exhausted. I slept 16 hours last night and am still tired, like I didn't get any sleep. I am on week 3 of the orange starter pack and am also crying a lot more than I used to as well. This medication is not for everyone. I called my psychiatrist and can't wait until she tells me how to wean off this medication and stop it for good."

1 / 10
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  • NYY...
  • April 7, 2017

For Epilepsy "Lamotrigine has been excellent for treating my seizures. Using this medication in conjunction with Fycompa, levetiracetam, and Vimpat I am seizure-free. If your medications do not get you seizure-free, please consider video EEG monitoring. Only after this was I able to be treated with the right medications. An absolute life changer. Vitamin B12 has been great to address all issues of lethargy or tiredness as a result of my meds."

10 / 10
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5 Report
  • NYY...
  • April 7, 2017

For Epilepsy "Lamotrigine has been excellent for treating my seizures. Using this medication in conjunction with Fycompa, levetiracetam, and Vimpat I am seizure-free. If your medications do not get you seizure-free, please consider video EEG monitoring. Only after this was I able to be treated with the right medications. An absolute life changer. Vitamin B12 has been great to address all issues of lethargy or tiredness as a result of my meds."

10 / 10
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5 Report

Frequently asked questions

  • Eri...
  • Taken for 1 to 6 months
  • September 6, 2021

Lamotrigine for Bipolar Disorder "Started off on Lamictal about 3 months ago. I was having severe mood swings and was diagnosed with Bipolar II. Lamictal has been by far the best medicine I’ve tried. No weight gain, not severely tired. I would take it around 5 pm after work and be totally fine. What I did notice was that it is associated with Stevens-Johnson syndrome. My doctor at the time bumped me up to 200 mg within 2 weeks (big mistake), and my body started reacting to it. I now have cystic acne on my face. The withdrawal from coming off the medication (because my side effects got bad... night terrors, cystic acne) was extremely irritably, lethargic, headaches. I’m talking to my doctor about lowering the dosage because we all know that finding medication to fit is hard. I also wanted this medication in case I became pregnant."

9 / 10
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2 Report
  • pyn...
  • Taken for 1 to 6 months
  • June 20, 2015

For Bipolar Disorder "I have just been diagnosed with bipolar II. I have been on antidepressants for 23 years and as I got older, the drugs didn't work as well. I suffer from depression, panic attacks, severe anxiety, phobias, and erratic mood swings changing daily, even hourly. So now I am on 300 mg Effexor, Valium, and have just started in increments of 25 mg of lamotrigine. Before this, I took Epilim, which was great, but within 2 weeks, I had a rash everywhere. Now I am up to 75 mg of lamotrigine and I have headaches, tiredness, sleeping up to 15 hours plus diarrhea, sick, depression, aggression, anxiety, the list goes on. It's been 6 weeks and I am losing it... my mental health team is useless. Will this get better???"

1 / 10
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10 Report

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  • Kod...
  • Taken for 5 to 10 years
  • June 25, 2025

For Bipolar Disorder "I am bipolar 2 and have an anxiety disorder. I’ve been on 200 mg for 6 years, and I notice a huge difference when I don’t take it. I get very, very, very moody. I’m still moody while taking it, but I’m worse when I don’t take it. It does make me a little bit sluggish/tired, but not enough for me not to be able to tolerate it. I don’t think I experience any other side effects. If you have a mood disorder, I definitely recommend giving it a try."

8 / 10
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  • J_J...
  • July 5, 2016

For Depression "I titrated up to 100 mg. After a couple of weeks on 100 mg, I started getting tired in the afternoon, cried most mornings, and had no motivation. It definitely made my depression worse."

1 / 10
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39 Report
  • Pop...
  • Taken for less than 1 month
  • March 4, 2020

For Depression "I've just started to take lamotrigine today, and it's making me feel calm but also feel sick. I'm going to continue with it to see how it is. Plus, I'm on venlafaxine 225mg, roll on more tiredness."

5 / 10
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15 Report

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Reviews may be edited to correct grammar/spelling or remove inappropriate content. Reviews appearing to come from parties with a vested interest are not published. This information is not intended to endorse any medication and should not replace the expertise and judgment of healthcare professionals.