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Tofranil for Depression User Reviews

Tofranil has an average rating of 6.4 out of 10 from a total of 7 reviews for the treatment of Depression. 57% of reviewers reported a positive experience, while 29% reported a negative experience.

Tofranil rating summary

6.4/10 average rating

7 ratings from 7 user reviews.

Compare all 183 medications used in the treatment of Depression.

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  • conrad
  • January 24, 2010

"I suffered from depression on and off till I was 33. My doctor prescribed a couple of medicines without success. Tried Tofranil because my mother took it in the late 1950s. Noticed a gradual improvement over 1 to 4 months with the full effect over a period of about 12 months. Medicine did not work at 100 mg, so went up to 250 mg, then 200 mg. Some small price side effects include dry mouth (gum, Tic Tac remedy). The medicine makes you sleepy about 2 hours after ingestion. Get ready for a good night's sleep, increased appetite, and feeling more relaxed than ever before. I remember the first sign of the Tofranil working was when I went outside one day and the sun seemed so bright, and I was happier to be alive. That was 25 years ago."

8 / 10
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249 Report
  • Crobo...
  • Taken for 1 to 6 months
  • May 8, 2024

"Started with 25mg of Tofranil and worked our way up to 75mg. It has been very effective for my depression/anxiety. At first, it made me a little drowsy, but that is no longer the case. I take it midday now. Blood pressure and pulse are within the normal range. No side effects besides a slight increase in appetite."

10 / 10
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1 Report
  • Anonymous
  • August 2, 2009

"At first this medicine seemed great. Was taking it for depression and generalized anxiety disorder. After a week on the lowest dose I started having bad side effects. I was shaving one morning and noticed my face, lips and arm felt numb. Doctor reduced my dosage to 10mg that worked okay for a week then same side effects."

4 / 10
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47 Report
  • Amy
  • Taken for 1 to 6 months
  • June 2, 2020

"Tofranil made me painfully constipated, very nervous, irritable, between doses, I'd get extremely weepy and emotionally distraught... it was the only time in my life that I felt live was too hard. When I started experiencing heart palpitations, I stopped taking it. I have CPTSD and Borderline"

2 / 10
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9 Report
  • Kam...
  • Taken for less than 1 month
  • February 17, 2016

"Waste of 75 bucks. My mood only increased slightly, and in exchange I got terrible bouts of dizziness and vertigo. Most of the time I felt like I'd been shot with a tranquilizer dart. Horrible experience. After only a week or so, I started to get nausea as well, so I had to stop. I regret spending money on this med."

2 / 10
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13 Report

Are you taking this medicine?

  • Anonymous
  • April 26, 2010

"Best and least expensive. Came off Celexa because of side effect. Be patient, it works in about 3 weeks."

10 / 10
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110 Report
  • Patty
  • Taken for 1 to 6 months
  • February 28, 2022

"I have been on it a few months and feel great. Was put on this for IBS and depression. Been great so far!"

9 / 10
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5 Report

Reviews may be edited to correct grammar/spelling or to remove inappropriate language and content. Reviews that appear to be created by parties with a vested interest are not published. This information is not intended to endorse any particular medication. While these reviews may be helpful, they are not a substitute for the expertise, knowledge, and judgement of healthcare professionals.