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Synvisc User Reviews & Ratings

Synvisc has an average rating of 6.4 out of 10 from a total of 64 reviews on Drugs.com. 61% of reviewers reported a positive experience, while 34% reported a negative experience.

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Osteoarthritis  
6.4
64 reviews for Osteoarthritis 362 medications
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Reviews for Synvisc

  • Pastry...
  • January 25, 2013

For Osteoarthritis "I had my first 3 injections 5 years ago and helped me for 5 years of pain free knees. Now 5 years later I have had my first injection yesterday and the next 2 in the next 2 weeks. Hope this one will also do the job for the next 5 years. Had no side effects whatsoever. I had a great doctor who did my hip replacement and also did the Synvisc injections. The key is to get a good doctor to do the injections. I highly recommend this injection."

10 / 10
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92 Report
  • Aneczka
  • July 25, 2019

For Osteoarthritis "I received SYNVISC INJECTIONS TO BOTH KNEES & I wish that I could have had the Steroidal injections instead of. The PA was bragging about this Medications ,so I said go ahead” if it’s more effective & the relief lasts longer then the Anti inflammatory steroid- I am ready “ Before the SYNVISC I could take a short walks with my dog, bend down to put his harness. ,but it was painful. Now,1 week since my third injection & I have terrible time trying to walk upstairs to my bedroom. The pain to both legs is unbearable, it feels as if I have fire in both of my thighs, knees & calves . My legs are very heavy, swollen & it feels as if I carry someone else’s legs. The pain & burning is non stop. I try to find somehow decent position with pillows to attempt to fall asleep. That is with taking my opioid pain medication,Gabapentin & Tylenol PM . Once I find a fairly comfortable position & use ice packs to calm the pain,I then am I am afraid to stand up & fall"

1 / 10
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48 Report
  • NeilB...
  • October 17, 2008

For Osteoarthritis "I have used Synvisc for 7 years (getting injections every 6 months) and my doctor said I could be the poster child for the treatment. It held off my knee replacement by at least 5 years. I'd recommend it to anyone."

8 / 10
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106 Report
  • Metac...
  • June 29, 2017

For Osteoarthritis "For anyone considering SYNVISC, I'd like to share that I've had both knees done twice & will continue to have the injections. Some background: I'm 59 yrs old, 5'6", approx 175lbs. The first time I had SYNVISC injects. (in both knees), it took about 5 weeks to experience the full benefits, but once it "kicked in," there was ZERO pain & complete fluid mobility! For almost a year, my knees felt "brand new!" I've recently had a second set of injections (both knees) and although there has been a bit more to pain in the recovery, each day there is definite improvement. I must caution anyone who gets these injections not to panic if there is noticable pain initially after the injections. Take it easy. It gets better!"

10 / 10
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57 Report
  • 64...
  • January 22, 2016

For Osteoarthritis "Before injections, had continuous pain in right knee; even during the night with little relief from aleve or motrin. Had some relief with physical therapy. After third injection, night pain was totally gone injections were two years ago. Now, only take Aspirin (arthritis back & body) when I am doing strenuous exercise or gardening. Can walk 6-8 miles a day with only slight discomfort. I have not needed more injections."

10 / 10
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58 Report

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  • Castp...
  • Taken for 1 to 6 months
  • May 30, 2015

For Osteoarthritis "Received three injections of Synvisc in January 2015. After 1st shot I experienced a relief from severe pain I had been experiencing. After the 2nd shot the stiffness I had been experiencing began to subside. After the third shot my knees stopped hurting and it has been uphill for almost 6 months. I experience an occasional catching of the right knee, but no significant pain."

9 / 10
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56 Report
  • Joseph
  • June 29, 2014

For Osteoarthritis "My wife recently took her second injections of synvisc one, about 6 months after the first. The first seemed to help reduce the knee pain a bit and she was looking forward to a similar experience. However it appears she had a severe allergic reaction to this second dose with many of symptoms described in the adverse reactions section of the clinical trials. By the afternoon of the injections she was experiencing severe back pain and thigh pain along with chills and shivering. By the evening she was not improving and her fever reached 104 with nausea and vomiting. We took her to the ER. They could find no evidence of infection through blood and urine test. Her fever and nausea improved but stomach still upset two days later."

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56 Report
  • Anonymous
  • July 26, 2009

For Osteoarthritis "I had my third injection 30 days ago. I find the improvement to my knee to be ongoing. Kind of a two steps forward one step back situation. I can now go up stairs almost normally. I no longer limp as I walk and the knee is relatively pain free. I have hopes that I will be able to play raquet ball again sometime in the future."

8 / 10
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65 Report
  • Schni...
  • January 28, 2016

For Osteoarthritis "Had my first shot in my left knee almost 3 years ago! Was amazing and still no issues to this day. My second shot was in the right knee which lasted a little over a year and just had the third in that same knee. Almost PAIN free in both. Far better than surgery!!! Highly recommend before opting for surgery!!"

10 / 10
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41 Report
  • Yonatan
  • Taken for 1 to 6 months
  • April 10, 2013

For Osteoarthritis "I had my first set of injections back in October 2012. I got almost immediate relief after a couple of days of swelling. It worked great for about three months then the effects started to wear off. I am hoping the second set of shots will work as well or better than the first."

9 / 10
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50 Report
  • Utah...
  • September 24, 2011

For Osteoarthritis "I first had the 3 in one injection 2 years ago with instant benefits and it lasted almost a year to the date. This is the 3rd time I have had the same injection but this time my knees are so swollen that I can not walk downstairs or get up from sitting. This is the second day and I am still hopeful that after the swelling goes down it will also last another year."

9 / 10
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52 Report
  • Miracle...
  • August 19, 2016

For Osteoarthritis "Initially had Synvisc-One injected into my knee, with only slight benefit (scale of 1-10, improvement to a 4 at best). Several months later had knees treated with the 3 injection Synvisc and it was a Godsend, on a 10 point scale the improvement has been as high as a 9! 3 months have passed and some minor pain has returned, but still maintaining a 7 on a 10 point scale."

10 / 10
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36 Report
  • Anonymous
  • May 24, 2009

For Osteoarthritis "Synvisc gave me significant, almost immediate relief from the bone-on-bone pain in my knees. Since then, as I continue to learn about my knee problems, I now understand that some of the pain is in the tendons around my knees, which are inflamed due to severe bow-legs. Still don't understand why the bowing is increasing with my age, but this forces my tendons to stretch in an incorrect manner, more on the inside of each leg than on the outside. Unfortunately Synvisc cannot address this problem, although it does provide a nice separation between the joint surfaces which also suffer from excess pressure on the inside portion of each knee. I am currently looking into shoe wedges to improve leg straightness by preventing excess supination."

9 / 10
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58 Report
  • Dogwo...
  • July 10, 2016

For Osteoarthritis "I had the triple shot 5 years ago to my left knee. My knee swelled up horribly and I could not do any of my workouts or dancing for 6 weeks. I was miserable and did not ever want to have it again. The upside is that after 6 weeks of pain it worked for 5 years. I just had the shot done to both knees and have not had any swelling and it has been 48 hours. My right knee is catching with any quick movements. Hope to have success after a few weeks. It did hurt really bad during the injection but I don't think that I received any local anesthetic this time. I think that may also contribute to the swelling when extra volume is added to the area. I also did not do any activities for 48 hours which is difficult for me."

9 / 10
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35 Report
  • Tilly
  • Taken for 5 to 10 years
  • November 9, 2016

For Osteoarthritis "I've had multiple Synvisc, cortisone and aerations over the last 5 years. The process is easy and pretty much painless. The results were beneficial, but the pain would always return (usually in 6 month intervals) and get progressively worse in frequnecy and intensity. When the pain got so bad it was difficult to walk, then I would schedule another appointment. A little over 1year and 3 months ago, I decided to start strengthening my leg muscles with weights as apposed to cardio by walking and the elliptical. Do not do the leg extensions as I found out these only make things worse. I do leg presses and reverse leg curls with a compression brace on both knees. Most of the pain is gone (90%) at this time period and is still getting better."

8 / 10
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33 Report
  • Bahiano
  • June 6, 2019

For Osteoarthritis "I had Synvisc on at least two or possibly three occasions, with a series of three injections one week apart-- This was perhaps 8 to 10 years ago (i.e. in2009 or 2011?) Each time I received very good results and relief which lasted two to 3 years. I regards this as an acceptable alternative to a total knee replacement."

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23 Report
  • Samiam
  • Taken for 5 to 10 years
  • October 27, 2020

For Osteoarthritis "Have had synvisc shots every 6 months over the past 7+ years and they provide excellent relief for up to 6 months after each shot. Both knees are bone on bone (no cartiledge left) but Synvisc shots, occasionally knee straps and icing when overdoing, provide great relief. They should be freezing injection site when giving injections. If you experience a great amount of pain when you are given the injection, find a new doc. Only had one PA that needed more schooling. That was painful but rest were just minimally uncomfortable. A great med!"

10 / 10
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17 Report
  • Ivy
  • April 5, 2019

For Osteoarthritis "I have osteoarthritis in both knees equally since 2008 so I got 3 Synvisc injections in the right knee in June 2008. My left knee never bothered me for some reason. Yes the injections are painful. However I don’t recall having any bad reactions. I keep reading in peoples’ comments that they last approximately 6 months. I have been pain free for 10 years! However now my left knee hurts like my right knee did 10 yrs ago, so I will be going back to get the same treatment done on my left knee. Hopefully with the same results!"

10 / 10
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22 Report
  • pgcpaul
  • Taken for 2 to 5 years
  • April 14, 2018

For Osteoarthritis "Had synvisc shots in both knees 5-years ago. Within days the knee aching I had suffered for several years went away. I began moderate exercise again and found knee stability much improved. No sense of the knee twisting or shifting unexpectedly. Went for two years before getting repeat injections. The improvement was again within days. Before the second shots my knees were still better than they had been before the first shots. The shots are momentarily painful, but NOTHING compared to constant low aches that were cured. I would recommend to everyone. Go before the knee deterioration is severe. This is not a alternative to knee replacement, it is what you do to prevent the need for knee replacement."

10 / 10
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23 Report
  • Stace...
  • March 17, 2016

For Osteoarthritis "I have had knee pain and swelling since age 12, it has gradually gotten worse over the years. Especially since I was diagnosed with Lupus, SLE & DLE. In the past year I have had excruciating pain. I went to the ortho and was diagnosed with Avascular Necrosis. I have since had surgery to remove some dead bone. The psin got better, then worse again so I got the shot of SYNVISC. It has really, really helped. I am just scared something will change amd I will be back on the sidelines of my own life. So much to deal with...."

9 / 10
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25 Report
  • Carol
  • Taken for 10 years or more
  • May 24, 2023

For Osteoarthritis "I had the three-injection Synvisc 11 years ago with great results. Before the injections, I could barely walk from the pain of moderately severe OA in my right knee. I did a lot of researching and reading reviews and learned the importance of 1) finding a doctor who has lots of experience with knee injections, 2) asking for a pre-lidocaine type shot, 3) VERY importantly - keeping that knee elevated for a full 24 hours after each of the three injections and for the next few days do not walk any more than necessary as this allows the injected fluid to stay within the knee and not travel down to the calf muscle. I’m going to go through this process again for both knees soon. I hope to have such amazing success again."

10 / 10
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5 Report
  • Anonymous
  • October 4, 2015

For Osteoarthritis "I received one shot and was told I couldn't have another for 6 months. It's been 3 weeks with no relief from the pain. I am still limping significantly. Hoping it is just a matter of waiting longer for it to take effect."

1 / 10
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23 Report
  • Angela
  • July 1, 2019

For Osteoarthritis "Had the first of three synvisc shots last week. Since then I have had terrible pain in the back of my knee, going down to my foot. Last time I had these shots three years ago, had a good reaction. This time around I spend my days crying. Supposed to have second shot tomorrow unless the doctor can prove this is normal, I'm not having 2nd shot."

2 / 10
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15 Report
  • Beegie
  • Taken for 2 to 5 years
  • May 7, 2019

For Osteoarthritis "Synvisc has worked wonderfully for me with osteoarthritis in my left knee. For me it lasts over a year and makes me feel more stable in walking and standing. I have a sister who had it and it did not work for her at all (she also has Rheumatoid in addition Osteo arthritis though). It seems to have a cumulative effect too, I need the injections less often over time. Has been more than 18 months and I only now feel like I could use another injection.,"

10 / 10
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15 Report
  • Anonymous
  • Taken for 2 to 5 years
  • August 25, 2017

For Osteoarthritis "I have been reading the reviews and I'm wondering if I got the same meds as, the folks who wrote these reviews. I got the shots in both, knees, not a numbing shot before the Synvis., Before shots it was very painful to even walk, needed a cane for some stability. The night of the first shots my knees we're tender but when my feet hit the floor the next morning I could not believe it. No pain, felt great. My Dr. Said that was very unusual. Pain subsides, over time not immediately. Received the series of 3 shots 4 years, ago this month. My knees are not as good as they were when I first got the shots but they are still better than before the shots. My doctor is surprised with results .I would advise anyone to go for the synvis injections."

10 / 10
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17 Report

Reviews may be edited to correct grammar/spelling or to remove inappropriate language and content. Reviews that appear to be created by parties with a vested interest are not published. This information is not intended to endorse any particular medication. While these reviews may be helpful, they are not a substitute for the expertise, knowledge, and judgement of healthcare professionals.