Hydroxyurea and Weight Gain: What Users Say

• T40...
• Taken for less than 1 month
• June 14, 2019

For Thrombocythemia "Female, age 40, essential thrombocythemia (ET) diagnosis for over 11 years. Was on hydroxyurea about 8 years ago and wasn’t feeling anywhere near as poorly as now, on one tablet a day for the last two weeks. Platelets before I started were about 1100. Platelets went down a bit after the first check and due back next week. Generally, I feel extremely tired, brain fog, difficulty concerning and verbalizing, not eating much but gaining weight. I would be asking to go back on interferon next time I see my consultant. I need to be on treatment as high levels are giving me extreme headaches. I’m from Ireland, so only pay up to €120 p/m for all my prescriptions, the rest is covered by my taxes."

• dal...
• November 23, 2015

For Thrombocythemia "I take this for myelodysplastic/myeloproliferative neoplasm. I got a lot of nausea. Some weight gain. Overall achy feeling. It has been working like it should. Only had to do one up change on dosage. I take 1 capsule twice a day."

• Mye...
• Taken for 1 to 6 months
• August 3, 2024

"I have been on hydroxyurea for 2 months, 500 mg once daily. I have not felt well since starting it. One week ago, due to side effects, it was changed to every other day. It has reduced my platelets, but I feel very weak and can barely do my daily activities. Yesterday, my nurse practitioner told me to stop the drug and to come in 4 days later for labs and consultation. While on hydroxy, I also had frequent nightmares, bloating, weight gain, and tingling of fingers and toes. I plan on asking if I could go to one pill per week on a trial basis to see if it could help at all with the platelets but have more tolerable side effects. I am beginning to feel anxious about the constant changes that create a slow decline in my well-being."

• gab...
• December 14, 2009

Hydroxyurea for Sickle Cell Anemia "Haven't been hospitalized since I started taking it. But I did gain a little weight."