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Hydroxyurea and Weight Gain: What Users Say

Brand names: Hydrea, Droxia, Siklos, Xromi

Weight gain: mentioned by 4 users (8.5%)

Based on user experiences from 47 Hydroxyurea reviews, the following table shows the most commonly mentioned side effects.

All user comments are moderated by Drugs.com. Each review is verified for relevance and screened for inappropriate content. Side effects are user-reported and not clinically verified.

tiredness 10.6%
headaches 8.5%
weight gain 8.5%
hair loss 6.4%
joint pain 6.4%
nausea 6.4%

Reviews for Hydroxyurea

Commonly mentioned side effects
  • T40...
  • Taken for less than 1 month
  • June 14, 2019

For Thrombocythemia "Female, age 40, essential thrombocythemia (ET) diagnosis for over 11 years. Was on hydroxyurea about 8 years ago and wasn’t feeling anywhere near as poorly as now, on one tablet a day for the last two weeks. Platelets before I started were about 1100. Platelets went down a bit after the first check and due back next week. Generally, I feel extremely tired, brain fog, difficulty concerning and verbalizing, not eating much but gaining weight. I would be asking to go back on interferon next time I see my consultant. I need to be on treatment as high levels are giving me extreme headaches. I’m from Ireland, so only pay up to €120 p/m for all my prescriptions, the rest is covered by my taxes."

6 / 10
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27 Report
  • dal...
  • November 23, 2015

For Thrombocythemia "I take this for myelodysplastic/myeloproliferative neoplasm. I got a lot of nausea. Some weight gain. Overall achy feeling. It has been working like it should. Only had to do one up change on dosage. I take 1 capsule twice a day."

9 / 10
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22 Report
  • Mye...
  • Taken for 1 to 6 months
  • August 3, 2024

"I have been on hydroxyurea for 2 months, 500 mg once daily. I have not felt well since starting it. One week ago, due to side effects, it was changed to every other day. It has reduced my platelets, but I feel very weak and can barely do my daily activities. Yesterday, my nurse practitioner told me to stop the drug and to come in 4 days later for labs and consultation. While on hydroxy, I also had frequent nightmares, bloating, weight gain, and tingling of fingers and toes. I plan on asking if I could go to one pill per week on a trial basis to see if it could help at all with the platelets but have more tolerable side effects. I am beginning to feel anxious about the constant changes that create a slow decline in my well-being."

5 / 10
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1 Report
  • gab...
  • December 14, 2009

Hydroxyurea for Sickle Cell Anemia "Haven't been hospitalized since I started taking it. But I did gain a little weight."

9 / 10
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39 Report

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