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Hydroxyurea and Joint Pain: What Users Say

Brand names: Hydrea, Droxia, Siklos, Xromi

Joint pain: mentioned by 3 users (6.4%)

Based on user experiences from 47 Hydroxyurea reviews, the following table shows the most commonly mentioned side effects.

All user comments are moderated by Drugs.com. Each review is verified for relevance and screened for inappropriate content. Side effects are user-reported and not clinically verified.

tiredness 10.6%
headaches 8.5%
weight gain 8.5%
hair loss 6.4%
joint pain 6.4%
nausea 6.4%

Reviews for Hydroxyurea

Commonly mentioned side effects
  • Hod...
  • Taken for 1 to 6 months
  • May 25, 2021

For Polycythemia Vera "After a few months of taking this medicine, I had severe joint pain, making it very difficult to walk. At one point, all of my joints hurt. I went to the ER once I could make it to the car. They could not find the problem. Next, to the primary care doctor, more blood work. I then saw a rheumatologist who did more blood work - nothing. Then I looked up side effects of the medicine and found that joint pain is a rare side effect. Went back to my oncologist and let her know what I found. She took me off the medicine, and within days, my joint pain was better. Very upsetting since I had asked already could it be the drug. Three doctors failed to check side effects! Back to phlebotomy."

1 / 10
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21 Report
  • 070...
  • Taken for 1 to 6 months
  • December 24, 2022

For Polycythemia Vera "Hydroxyurea has been very good for me. I have been diagnosed with Polycythemia Vera about 7 months ago. After a few months of phlebotomies with no success, I started on hydroxyurea, and the results have been great. All my numbers are in acceptable ranges, and the only side effect has been joint pain in my feet. I had to get off the medication when I contracted COVID, and all of the disease symptoms roared back. After being back on it for a couple of months, my numbers are back to normal, and I feel great."

9 / 10
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10 Report
  • gre...
  • Taken for 6 months to 1 year
  • May 15, 2023

For Thrombocythemia "Worked well to control platelet count. Caused muscle soreness, hair loss, joint pain, increased depression, exhaustion, and possibly 'chemo brain.'"

5 / 10
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1 Report

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