Hyaluronidase and Burning: What Users Say

• Ano...
• Taken for less than 1 month
• June 11, 2021

For Dissolution of Dermal Filler "I had Hyaluronidase injections used on my face to dissolve filler, and it has caused nerve damage, pain, and burning sensation. I experienced dry eyes, blurred vision, and it damaged my skin permanently. I have experienced volume loss, skin laxity, sunken eyes, changes in skin texture, and pain in the left side of my jaw. I am unable to open my mouth properly because my jaw clicks and locks. I had the injection over a year ago, never had any of these problems before, and it is still ongoing. It was an awful experience."

• Ali...
• Taken for 1 to 6 months
• December 24, 2020

For Dissolution of Dermal Filler "I had filler under eye dissolved with hyaluronidase, about 20 units in total in one week. It gave extremely serious systematic issues that is not known by any doctor, but there are plenty of people that have exactly the same after hyaluronidase. It began with softening, volume loss in my cheeks and chin. Then it started to affect all my connective tissues around the body, my eyebrows, forehead, my eyes went deeper inside, and my scalp became bony. Every day I have burning sensations under my skin. All my body changed. I am only 23 and it affected all my body connective tissues. It's only been 5 months after and it's still progressing! I was a very beautiful girl before, I was active. Now my life changed so much. And no one knows that connection, so lots of doctors will think that you are lying and crazy. It can trigger this systematic issue, which is a very life-threatening disease that you will get and no one will help with that!"

• LAS...
• Taken for 1 to 2 years
• February 7, 2021

For Dissolution of Dermal Filler "I am permanently disfigured because of hyaluronidase aka Hylenex. It was unnecessarily injected into my lip damaging my nerve and destroying the area of my lips and chin, exposing my lower teeth. The enzyme spreads! It has been over a year and I still feel the stinging and burning everywhere the enzyme has spread to. Doctors lie and say this product will not damage you! No help for people damaged by this enzyme! How can the manufacturers of hyaluronidase create a product this dangerous without creating something to counteract its effects, should something go wrong? I have indentations in my face, and when I try to smile, my lower teeth are exposed, and my 'smile' is lopsided! I will never be able to smile again for the rest of my life!"

• Eas...
• January 26, 2022

For Dissolution of Dermal Filler "I only had filler dissolved in my lips, and the Hylenex spread over months into my entire face and body. It was the most traumatic experience of my life. I went to multiple doctors for help, but received only denial and confusion about what happened. My eyes were the scariest part. I got corneal inflammation and extreme dry eye. I had so much eye pressure. I went to multiple eye doctors for help. I now have an aqueous deficiency in my eyes. My cheeks dropped, and my face burned for 8 months. I would wake up in the middle of the night in pain from the burning, I would be running to the sink for cold compresses. I was extremely thirsty in the first few months and couldn't drink enough water. My eyes have sunken into my head, I believe because the supporting tissue around them has changed. The skin on my entire body has thinned. I can see veins that were not present before-all from the dissolver in my lips. Why is the FDA allowing all of us women to suffer and not putting a warning label? No studies of it being used in people's faces."

• Evi...
• November 13, 2021

For Dissolution of Dermal Filler "This was used to remove filler. I am three months out since it was used. Affected my whole face. Eyes destroyed with non-functional tear ducts. Some days I'm not able to open them due to pain. Upper lids dried out causing more severe pain. Lower eyelids are kind of no longer attached to eyes. The whole body burning and the pain makes me vomit on a daily basis. Wounds won't heal anymore and bruises don't go away. Oculists and doctors don't take you seriously - don't you ever believe you will get any help wherever in the world you live. This substance easily steals your life away and from then you are alone. Don't you ever use this substance. Don't do it. Please, wait for the filler to dissolve on its own. Now I have told you."

• Too...
• Taken for 6 months to 1 year
• July 9, 2022

For Dissolution of Dermal Filler "Beyond devastated and hoping this was in my head like the doctors like to make you believe. I am destroyed. Sunken face, nerve damage, blurriness, burning… My relationships and job are downhill. Neck has aged over a decade-my cheeks dropped, and I had the best smile and best face and am honestly suicidal at this point. This is not a lie, people, we need to make something happen to get people to listen!"

• Mar...
• Taken for less than 1 month
• May 7, 2023

For Dissolution of Dermal Filler "Awful drug, do NOT use, please. I had dermal filler under my eye and jawline dissolved with hyaluronidase 2 weeks ago! It melted the muscles in my legs within 7 days (I used to go to the gym twice a day). I’m getting chills, a burning sensation, blurred vision, extreme fatigue, and I can’t focus. I went to the Dr to get an explanation for the loss in muscle, she said I’m having nerve degeneration! It’s happening all over my body: my forearm, my shoulders, my legs, my feet. My sex drive is completely gone. It’s melting my connective tissues and causing pain in the jaws. My face is aging by the minute (falling off basically). I lost all purpose in life, I was a very successful man (37 years old). Please don’t use! Don’t, please! This drug will steal your soul from you! My family is devastated, no words can explain the damage this drug has done to my life. DO NOT use! Don’t get fillers! And if you already got filler, never ever agree to dissolve."

• Lif...
• Taken for 1 to 6 months
• January 30, 2022

For Dissolution of Dermal Filler "This substance is very intelligent and extremely evil. I'm 5 months in and no signs of withdrawal. It attacks in sessions - you never know where the next attack will be. My whole body is affected - now my joints and tendons. Eyes totally destroyed. I went from 100% working to being disabled overnight. Ugly big brown spots on my skin are emerging from nowhere. Facial skin always edematous and jelly-like. The palms of my hands have dried out and the skin on the tops of my hands is wrinkly and loose. Skin collapses on top of blood vessels, making them bulge on my hands and feet. The burning pain and agony are unbearable due to the targeted slow process. The substance is hiding and is manufactured to look like the body's own. Doctors will never find it and will give you substitute explanations. Not sure I will survive this. There's no antidote existing."

• RBK...
• Taken for 1 to 6 months
• August 1, 2022

For Dissolution of Dermal Filler "If your doctor tells you it's safe, run! I thought I could take a risk, that it's used all the time. I saw these reviews, but my doctor promised he's never seen any side effects. These past two months have been hell. I've had face burning, head burning, eye burning, dry eye, fatigue, terrible eye bags, volume loss, saggy skin. I don't recognize myself anymore. I am getting tested for nerve damage this week. If things don't get better, I don't know how I can live like this."

• Eve...
• Taken for 1 to 2 years
• June 27, 2022

For Dissolution of Dermal Filler "I experienced a nightmare from hyaluronidase. A year ago, I had hyaluronidase in my face to reduce fillers. After that, I felt a burning sensation and terrible nerve pain. Dry eyes, nose, mouth, tachycardia, etc. It's been a year, and I'm still suffering from pain, especially dryness in the mucous membranes. Right now, I can see dots and lines and blurry. Please don't use hyaluronidase, even if the doctors say it has no side effects. I used to be healthy and never had any problems."

• My ...
• August 10, 2022

For Dissolution of Dermal Filler "As a longtime systemic sufferer from this awful stuff, I have used all my past year studying science reports on hyalase, which mostly are propaganda. No scientist or surgeon is willing to study negative long-term effects if you get this poison in your bloodstream. Here is my conclusion about what happens: -The Hyalase addressing the filler enters your overall body tissue via the vessels. -The filler starts the dissolving process, which can go on for years. Fillers are hard to dissolve and will always leave traces of particles. -Filler (or particles left) is trying to destroy itself - often in waves/flare-ups. -Since I believe everything in the body is connected, I believe everywhere the hyalase has been in contact with also has the same flare-up destruction when the filler (or leftover particles) again and again tries to self-destruct, hence the overall burning."

• Dev...
• Taken for 1 to 2 years
• July 12, 2022

For Dissolution of Dermal Filler "Now I'm 1 year in - Hyalase is dangerous. I obviously got this poison in my blood, and it rapidly attacked absolutely everything in my body - from the collagen/connective tissue to the intestines. Still, I have this suspicion that the enzyme might, along the way, have left the system and that the constant feeling of being sick is the continuous swelling and dissolving of the filler in my face. I don't tolerate chemicals well, and however you look at it, the Restylane is fabric made. I suspect the rapidly dissolving filler (which actually is chemical) affects my whole system now. My blood work shows signs of alcohol and tablet abuse. I never touch alcohol and never take painkillers, even though the burning pain in my face and eyes makes me scream sometimes. The continuous poisoning of my body has also now made my thyroid gland malfunction, and the hormone production is declining. Maybe being allergic to chemicals has contributed to severe complications in many of us? Thoughts?"

• Wor...
• Taken for less than 1 month
• August 21, 2022

For Dissolution of Dermal Filler "I had my cheeks dissolved 4 days ago, and so far, so good. I am not experiencing anything that has been described above. No burning, no dry eyes, no overly aggressive volume loss or dents. I feel the dissolver did what it was supposed to do. I had a large amount of Juvéderm Voluma in my cheeks for over 2 years that had started to harden and look very odd when I smiled. Getting them dissolved was the best thing I have done. I look like myself again. It was done by a board-certified PS, 75 units in each cheek diluted with lidocaine. I’m very happy with the results."

• Anonymous
• Taken for 1 to 6 months
• October 23, 2022

For Dissolution of Dermal Filler "Systemic effects. Burning skin all over my body, especially arms, hands, and chest, saggy skin. 1 month post HYA, still burning. This is so awful."