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Hyaluronan User Reviews & Ratings (Page 5)

Brand names: Orthovisc, Monovisc, Hymovis

Hyaluronan has an average rating of 6.2 out of 10 from a total of 296 reviews on Drugs.com. 56% of reviewers reported a positive experience, while 34% reported a negative experience.

Reviews for Hyaluronan

Commonly mentioned side effects
  • mb6...
  • April 9, 2015

For Osteoarthritis "At my first three injections on my right knee, it didn't work right away, but now, two weeks after, what a relief in pain from a 10 to a 2. Now I asked to do my left knee, I can't bend it when I walk. Hope it works, then I won't limp when I walk. Excited."

8 / 10
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  • Woo...
  • Taken for 1 to 2 years
  • September 4, 2018

For Osteoarthritis "My first round of Orthovisc I was told would last 6 to 9 months for my bone-on-bone knee pain. The shots were painless, and I was pain-free for two years. Now I am back for my second round. It sure beats knee replacement, which was my only other option. I am having pain again, so I am ready for round two. Hope it lasts as long this time. I highly recommend it."

10 / 10
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26 Report
  • Mel...
  • Taken for less than 1 month
  • October 10, 2019

For Osteoarthritis "I have had knee pain for several years. I finally broke down and allowed my doctor to use these new gel injections in both my knees. The first 48 hours, I ran a low-grade fever followed by debilitating pain. We decided not to do the second injection because of this reaction. I am very disappointed in my experience with this medicine. I didn’t read the reviews prior to having this procedure, which was my fault, but I’m waiting for the pain to subside now. Hoping this gets better soon."

1 / 10
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25 Report

Frequently asked questions

  • Sav...
  • June 6, 2021

For Osteoarthritis "I've tried knee injections for over 5 years now. My orthopedic surgeon initially started me on Synvisc. I never had much relief, and it was short-lived. Fast forward to this past week, and my new orthopedic surgeon used Monovisc on me. Right knee injection - I felt absolutely zero pain. Left knee, I felt heavy pressure, but not something I couldn't handle. Using the numbing spray before the initial shot was all I needed. I felt zero pain. So far, so good. I feel a lot better, but I'm still waiting for a more 'stable' feel from my knees - especially my right one. It's comforting to know that some folks on here state that it takes a week or more to have the full benefit from the injections. Looking forward to feeling 'normal' again!"

9 / 10
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18 Report
  • yog...
  • Taken for less than 1 month
  • December 1, 2016

For Osteoarthritis "I got my first injection today, no discomfort at all with the injection!!! My knee is already feeling better, I drive a stick shift, and I had no pain driving today!! I'm very hopeful this gives me relief!!"

9 / 10
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31 Report

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  • Ant...
  • December 10, 2016

For Osteoarthritis "I received one injection in both knees for four weeks a month ago. Have RA, OA, and had tibia plateau fixation in both legs in 2009 after a car hit me. The injections did not give me any kind of pain relief at all. As a matter of fact, today, my right knee feels worse than before the injections because it's hurting even though I didn't walk or stand up…"

1 / 10
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32 Report
  • sus...
  • July 26, 2013

For Osteoarthritis "This is my 3rd time for injections, but it has been 7 yrs. since the last one. The shots hurt so much I cried. (I am 66 and need replacement surgery.) The doc did the injections with my knees bent, he said, because the cartilage is gone and it creates a bigger space. It's been 5 hrs since the injections. Feels better, icing every hour. Hope next week is better."

5 / 10
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40 Report
  • Dra...
  • Taken for less than 1 month
  • July 3, 2018

For Osteoarthritis "Had my first Monovisc shot, which was also my first gel shot ever. It didn’t hurt too much to get. Six hours after I got the shot, I was in the ER with feet Mickey Mouse would have envied, having an asthma attack and with my throat partially swollen shut. It was not fun times. Worse, after a week of pain but decidedly less creaking, my knees hurt worse than ever, and now when they buckle, the pain is excruciating for hours instead of a few seconds like before. It’s truly miserable. My allergist said there’s no data on allergies to Monovisc, but that is all I can think it was since everything started an hour after the shot and deteriorated rapidly."

1 / 10
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28 Report
  • Lib...
  • Taken for 6 months to 1 year
  • November 8, 2016

For Osteoarthritis "About 11 months ago, I received the single dose Monovisc. It was painful to receive the shot, and the pressure was great as it was injected. It took about 3 weeks for me to feel better. Before the shot, I had a high level of constant pain from bone-on-bone on the outer edge of my knee. A pocket of fluid had formed on the outside for weeks, and I had been waking up with knee pain during the night for quite some time. This greatly improved my knee pain. It didn't take me to 0 pain but definitely reduced it. About 5 weeks ago, I felt the pain creeping up, the fluid forming, and began to wake up during the night on occasion. I called the doctor and scheduled the next one, which I'll get in a few days. Better than pain or surgery!"

9 / 10
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27 Report
  • 48 ...
  • Taken for 6 months to 1 year
  • October 15, 2017

For Osteoarthritis "Osteoarthritis in the right knee eventually led to bone on bone. After my last scope in November 2015, the pain persisted to where I had a steroid injection. It relieved some of the pain for 2 months (considered non-effective according to FDA), then the excruciating pain returned. The last nonsurgical option was Orthovisc, which all 3 injections were very painful. I didn't experience relief until 2-3 weeks after the last injection. I have been pain-free, with an occasional very brief episode (seconds) of some pain. Now it's October 2017, and it's been wearing off. But 12 months' worth of no pain was definitely worth it. So glad I toughed it out!"

10 / 10
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  • Anonymous
  • December 5, 2009

For Osteoarthritis "I just had my second injection on 12/2-one more on 12/9. The first injection was very painful, and my knee was sore for two days. The second injection did not hurt at all, and my knee was fine immediately after. This knee pain has been going on for two years, and I finally have relief. I'm just hoping it lasts longer than six months. I would definitely advise anybody who has this problem to at least try it. It is working for me!"

8 / 10
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44 Report
  • Cat...
  • Taken for 1 to 6 months
  • March 14, 2019

For Osteoarthritis "Orthovisc was one of the biggest mistakes I ever made. The doctor said this would help my osteoarthritis, but it is much worse than when we started. The first shot was very painful, the second was much worse. The doctor convinced me to have all four shots. Now I can hardly walk, in constant pain. So sorry I had the Orthovisc shots. They should be off the market."

1 / 10
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  • Anonymous
  • March 20, 2015

For Osteoarthritis "I have arthritis in both knees. One is severe, bone-on-bone, the other is moderate. So they started injections in my left knee first, as the right one wasn't bothering me too much, as the cortisone shots were still slightly effective. So I got two shots-not too bad as far as pain. I went to get the third one, and the doctor didn't take her time like before to find just the right spot, and she injected me. As soon as she started putting the fluid into my knee, I felt a burning liquid feeling going from the injection site (the outside of my knee to the inside of my knee). It didn't stop there. It felt as if she put more in, like my knee was going to explode out the side. I was not expecting that. I just held my breath, and when she was done, I said, 'Wow, that hurt. Why?'"

5 / 10
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  • Suz...
  • Taken for less than 1 month
  • January 30, 2016

For Osteoarthritis "11-23-15 I got shot #1 of Orthovisc. The shot itself was not painful, but afterwards, the pain became intense. There was swelling, redness at the injection site, and at times, excruciating pain. 11-30-15 I was given a cortisone shot to get the reaction under control. 12-3-15 I got shot #2. The injection wasn't painful, but afterwards, it was horrible. There was redness at the injection site; swelling from the thigh to the ankle; fatigue; weakness; mild edema; body-wide pain, with arthritis-type pain in my joints and the excruciating pain in the knee. 12-7-15 Given a prescription for Prednisone. Did not receive shot #3. Finally, for the last couple of days, I can say the symptoms are about half gone. 1-29-16 Do your research."

1 / 10
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  • Aun...
  • Taken for 1 to 6 months
  • March 24, 2018

For Osteoarthritis "I would not recommend Monovisc. I'm 37 years old with significant OA in my knee, and it started with a bone chip injury when I was 21. The injection itself was painful enough to make me cry, and I'm not a crier. (Note to Orthopedics - cold spray before injection does NOTHING!) I experienced extreme pain in the 2 weeks following the injection. Four and a half months later, my knee is worse than it was before - more acute pain, joint feels weaker, and I need to rest and wear my knee brace more often. I love to be active, and OA hinders this. :-("

1 / 10
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  • bet...
  • December 3, 2015

For Osteoarthritis "I don't know if this has anything to do with Orthovisc, but I have had continual shortness of breath, exhaustion, and waves of nausea, especially following the second dose (I had 4). These symptoms have continued for weeks, and the hospital and doctors can find no other cause."

1 / 10
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  • Bob...
  • Taken for 2 to 5 years
  • May 16, 2024

For Osteoarthritis "I have used Monovisc about three years ago and pain free for a year and a half. Switched doctors and tried Orthovisc injections, which are given once a week for 3 weeks. Had headaches for 3 weeks and knees stayed stiff for 4 weeks. Could not play golf. Lasted about 9 months, though, but did not like the initial procedure. Tried Durolane, which was terrible. Headaches, knee pain, and only lasted 2 months. Went back to my doctor and requested Monovisc. It has been 5 days since my injections in both knees, and no headache and slight discomfort, stiffness in both knees, which is gone in four days. Looking forward to a year and a half of painless knees. I see people complain about painful injections. That is because the doctor is in a hurry or doing a poor job. A good doctor gives injections pain-free."

10 / 10
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  • Biz...
  • Taken for 2 to 5 years
  • February 17, 2021

For Osteoarthritis "I have had other hyaluronic acid injections, and Hymovis was a lot better, in my opinion. The other injections did work, but not as good as Hymovis. Plus, Hymovis seems to last longer for me. My knee did feel a little wobbly for about a day after the injections."

9 / 10
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  • PKi...
  • Taken for 1 to 2 years
  • July 18, 2017

For Osteoarthritis "I have bone-on-bone in my left knee, so bad I was ready for a replacement. My Dr. suggested we 'give the shots a shot', if they don't work, we'll take the next step. He is an expert at giving shots to the knee as I felt no pain, just a bit of pressure as he did each injection. At first, I was very disappointed as I didn't feel any difference. About a month and a half after we finished the series, I noticed I had no pain in my knee! It lasted about a year, going in for another 3 shots next month. Dr. says it works for some, but not all, and I'm glad I 'gave it a shot'."

9 / 10
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  • Pat...
  • September 8, 2020

For Osteoarthritis "I have chondromalacia and arthritis in my knees, with the left being worse. I had a steroid injection in the left, which didn't seem to help much. Several months later, I had the Monovisc injected. There was a lot of pressure at the time of injection. Within a few days, it gave a lot of relief for about 6 months. I had a second injection 2 and a half weeks ago. The actual injection was about the same, but as soon as I started walking, I had pain, and I told the nurse I didn't remember it hurting like this last time. To make a long story short, for a few days after the injection, the pain was bad. I had to use a cane to walk, and there was no way I could use stairs. Since then, the pain has decreased, but my knee is more painful than before the injection. I sent a message to my provider. He responded that he had a couple of other patients that had the same type of reaction after the second injection and that they had no improvement. Maybe it will improve, but I won’t do this again."

4 / 10
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  • Bat...
  • February 14, 2019

For Osteoarthritis "My first injection was easy peasy, the second injection, easy peasy. I'm currently on the 3rd injection, and it has been a killer. It feels like the space in between my bone was separating, it was an odd, painful feeling and hurts 2 days later. I have swelling on top of my knee and around the injection site. However, this knee has been a mess since my arthroscopic surgery last year, so this could have something to do with excessive swelling. I'm hoping this will give me my life back. UPDATE: I had to do the 4th injection a week later than planned and, oh my gosh, what a godsend! This injection felt like my 1st injection (easy peasy). I highly recommend taking a week break between the 3rd and 4th injections. My ortho told me I won't see real benefit for several weeks. I currently can walk without excruciating pain."

8 / 10
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20 Report
  • Mel...
  • Taken for 6 months to 1 year
  • October 28, 2016

For Osteoarthritis "I received my first set a year ago as I have no kneecap. Afterwards, I was able to do physical therapy. I was able to do exercise that I hadn't done since I was a child. This medication lasted a year. I started to feel the same pain about a month or so ago. I contacted my Dr., and we are doing it again. This injection has made such a difference in my life. I am very grateful for it."

9 / 10
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26 Report
  • Nea...
  • Taken for less than 1 month
  • May 22, 2019

For Osteoarthritis "I had a Monovisc shot to my knee less than one month ago, I am having knee pain, extreme warmth, and joint pain with back pain. This is my first time getting this shot, and not a very good outcome so far. I made an appointment to see my doctor."

4 / 10
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22 Report
  • Tri...
  • Taken for 1 to 6 months
  • May 20, 2022

For Osteoarthritis "I have bilateral severe bone-on-bone arthritis in both knees. I have used cortisone injections that only worked temporarily for about a month. Then I decided to use the gel injection Monovisc - the worst thing I could’ve ever done. The pain started immediately at the injection. My knees are 10 times more painful now than before the injection. It is horrible pain now after exhausting everything and methods that I have to have total knee replacement. Monovisc is the worst injection I could’ve ever done. I have all the side effects magnified five times. I can barely walk, and it’s only been one month. It has been horrible, the worst pain I have ever experienced, in daily chronic debilitating pain. This did not go well for me. If you have severe arthritis, Monovisc gel will aggravate the inflammation to the 10th power. I can barely walk. I don’t recommend. I had the one shot Monovisc. The worst decision that I could have made searching for some pain relief."

1 / 10
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11 Report
  • Jan...
  • Taken for 1 to 6 months
  • October 9, 2018

For Osteoarthritis "I started the knee injection on July 31, 2018, and completed 3 injections in both knees on Sept 5, 2018. 5 weeks since my last injection and knees are greatly improved. I am 71 years old. The weeks prior to this week were worrisome. I was thinking they were not going to work. But this week has shown great improvement. I started riding my three-wheel bicycle, and that has helped a lot. I would highly recommend the injections, however, I would add, listen to your doctor and rest for 48 hours and go slow. Expect it to take several weeks to show improvement. Well worth it."

9 / 10
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Reviews may be edited to correct grammar/spelling or remove inappropriate content. Reviews appearing to come from parties with a vested interest are not published. This information is not intended to endorse any medication and should not replace the expertise and judgment of healthcare professionals.