Zoladex for Breast Cancer, Palliative User Reviews

• kik...
• March 1, 2010

"I am 32 years old, and I have to take Zoladex for 3 years with the medicine Tamoxifen for 5 years. I have been on Zoladex for about a year now. Some of my side effects include severe mood swings, hot flashes, loss of menstrual cycle, weight gain (28 pounds so far), loss of energy, swelling of hands, and forgetfulness."

• Spr...
• Taken for 2 to 5 years
• February 26, 2016

"I'm now 33 and have been taking Zoladex for 2 years alongside Tamoxifen for 10 years in the UK. This medication gave me the confidence not to have chemotherapy, and for this, I am grateful. The downsides are pretty bad, though. I agree with the previous reviewer. Mood swings, increased body temperature, severe hot flushes and night sweats (trying acupuncture to help), increased sex drive, no periods, significant weight gain! I went from 7.5 stone to 9.5 stone in 18 months, having never had much fluctuation in my weight ever before. My bra size also increased 3 cup sizes. I have gone from being very healthy and slim to quite flabby and 'technically' (BMI) overweight - which hits hard when you feel low self-esteem because of surgery anyway."

• 36y...
• Taken for 1 to 6 months
• October 27, 2022

"Very bad reaction. I'm a 36-year-old woman diagnosed with breast invasive ductal carcinoma. After lumpectomy, chemotherapy, radiation, I was put on Zoladex, and I developed rheumatoid arthritis after 2 months of the 1st Zoladex injection. Very bad hot flushes, I felt I was burning alive. Bad temper too. Talked with my oncologist and refused to keep doing Zoladex. After 2 months without Zoladex, I no longer have hot flush symptoms, and arthritis symptoms have improved but not gone."

• Sur...
• Taken for 1 to 6 months
• October 1, 2019

"The side effects from this drug have not been as bad as I expected them to be. Hot flushes are the worst of it, particularly at night. I have gained a small amount of weight, but I am trying to eat healthily and exercise regularly to try and combat this."

• sam...
• Taken for 1 to 2 years
• October 10, 2019

"Twenty-one years ago, I was given Zoladex as breast cancer treatment. I stopped treatment after 18 months as the hot flushes were severe. Now, two decades later, they are still horrendous. Has anyone else had this experience?"